个人简历

中共党员，博士，副研究员，博士生导师（中药学）。入选第三批天津市人才发展特殊支持计划“青年拔尖人才”与天津市“131”创新型人才培养工程（第二层次）；天津市静海区青年联合会第一届委员会委员。国家自然科学基金函评专家，中医药规范研究学会（GP-TCM RA）会员，中华中医药学会中药分析分会会员；Acta Pharm. Sin. B、J. Chromatogr. A、Phytomedicine等SCI期刊审稿人。
2012年9月在北京大学获理学博士学位，2013年3月至2015年8月在中科院上海药物研究所上海中药现代化研究中心进行博士后研究，出站后获聘副研究员，2017年人才引进至天津中医药大学。

研究领域

标准导向的中药整体性质量控制方法研究。致力于中药复杂体系系统表征与整体性质量评价新技术研究，以“整体观”为切入点，以“深入研究-浅出标准”为指导思想，围绕中药“系统物质基础阐释、整体性鉴别与全面质量评价”三个方面，构建基于“多维色谱-高分辨质谱、多维信息数据库、代谢组学/脂质组学”的现代中药质量研究技术体系，示范性地应用到人参属、钩藤属、红花属等中药材与相关成方制剂物质基础与质量评价研究。特别是对三种常见名贵中药人参、西洋参、三七的化学成分与整体性质量控制方法进行了持续、深入的研究。

近期论文

[1] Lingling Fu1, Hui Ding1, Lifeng Han, Li Jia, Wenzhi Yang*, Chunxia Zhang, Ying Hu, Tiantian Zuo, Xiumei Gao*, Dean Guo*. Simultaneously targeted and untargeted multicomponent characterization of Erzhi Pill by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry, Journal of Chromatography A, 2019, 1584, 87-96. (IF: 3.716)
[2] Xiaojian Shi1, Wenzhi Yang1, Shi Qiu, Jinjun Hou, Wanying Wu*, Dean Guo*. Systematic profiling and comparison of the lipidomes from Panax ginseng, P. quinquefolius, and P. notoginseng by ultrahigh performance supercritical fluid chromatography/high-resolution mass spectrometry and ion mobility-derived collision cross section measurement, Journal of Chromatography A, 2018, 1548, 64-75. (IF: 3.716)
[3] Wenzhi Yang, Yibei Zhang, Wanying Wu, Luqi Huang, Dean Guo*, Changxiao Liu*. Approaches to establish Q-markers for the quality standards of traditional Chinese medicines, Acta Pharmaceutica Sinica B, 2017, 7, 439-446. (IF: 6.014)
[4] Xiaojian Shi1, Wenzhi Yang1, Shi Qiu, Changliang Yao, Yao Shen, Qirui Bi, Min Yang, Wanying Wu*, Dean Guo*. An in-source multiple collision-neutral loss filtering based nontargeted metabolomics approach for comprehensive analysis of malonyl-ginsenosides from Panax ginseng, P. quinquefolius, and P. notoginseng, Analytica Chimica Acta, 2017, 952, 59-70. (IF: 5.123)
[5] Wenzhi Yang, Xue Qiao, Kai Li, Jingran Fan, Tao Bo, Dean Guo*, Min Ye*. Identification and differentiation of Panax ginseng, P. quinquefolium, and P. notoginseng by monitoring multiple diagnostic chemical markers, Acta Pharmaceutica Sinica B, 2016, 6, 568-575. (IF: 6.014)
[6] Shi Qiu1, Wenzhi Yang1, Xiaojian Shi, Changliang Yao, Min Yang, Wanying Wu*, Dean Guo*. A green protocol for efficient discovery of novel natural compounds: characterization of new ginsenosides from the stems and leaves of Panax ginseng as a case study, Analytica Chimica Acta, 2015, 893, 65-76. (IF: 5.123)
[7] Wenzhi Yang, Min Ye*, Xue Qiao, Chunfang Liu, Wenjuan Miao, Tao Bo, Haiyan Tao, Dean. Guo*. A strategy for efficient discovery of new natural compounds by integrating orthogonal column chromatography and liquid chromatography/mass spectrometry analysis: its application in Panax ginseng, Panax quinquefolium and Panax notoginseng to characterize 437 potential new ginsenosides, Analytica Chimica Acta, 2012, 739, 56-66. (IF: 5.123)
[8] Wenzhi Yang, Min Ye*, Feixia Huang, Wenni He, Dean Guo*. Biocatalysis of cycloastragenol by filamentous fungi to produce unexpected triterpenes, Advanced Synthesis & Catalysis, 2012, 354, 527-539. (IF: 5.123)