个人简历

教育背景
2003年9月-2007年7月，就读于鲁东大学生命科学学院生物科学专业，获理学学士学位
2007年9月-2010年7月，就读于山东师范大学生命科学学院动物生理专业，获理学硕士学位
2010年9月-2013年7月，就读于南开大学医学院生理学专业，攻读博士学位
所获奖励
2014年6月天津中医药大学青年教师基本功竞赛二等奖
2014年10月天津市第十二届青年教师教学基本功竞赛三等奖

研究领域

（1）熟练掌握细胞培养及相关实验检测技术，包括增殖实验、免疫组化、Western Blot、细胞凋亡检测、细胞活性氧簇检测等
（2）熟练掌握动物实验的各项操作如麻醉、腹腔注射、脑内微量注射、脑立体定位技术，核团损毁技术，心脏灌流，胚龄取器官等，掌握动物实验的行为学检测手段、电生理检测技术及病理检测方法如Morris水迷宫，LTP的记录
（3）掌握基本膜片钳技术，及钙荧光测定技术，能够与离子通道相互结合，进行机制研究
（4）熟练掌握各种仪器使用如冰冻切片机、石蜡切片机、超速离心机、荧光显微镜、立体定位仪、电极拉制仪、电泳仪等

近期论文

1. Pengjuan Xu,Jing Xu, Zhigui Li, Zhuo Yang. Expression of TRPC6 in Renal Cortex and Hippocampus of Mouse during Postnatal Development, PLoS ONE 7(6): e38503.SCI, IF=4.092
2. Pengjuan Xu,Jing Xu, Shichang Liu, Guogang Ren, Zhuo Yang. In vitro toxicity of nanosized copper particles in PC12 cells induced by oxidative stress, J Nanopart Res (2012) 14:906. SCI, IF=3.28
3. Pengjuan Xu,Jing Xu, Zhigui Li, Zhuo Yang. Nano copper induced apoptosis in podocytes via increasing oxidative stress, J Hazard Mater, 241-242 (2012) :279-286. SCI, IF=4.173
4. Pengjuan Xu,Zhigui Li, Qinjun Xuan, Zhuo Yang. Different expressions of large-conductance Ca2+-activated K+ channels in mouse renal cortex and hippocampus during postnatal development，Appl Immunohistochem Mol Morphol, Accept 29-Sep-2013, 2013.SCI，IF=1.832
5. Jiajia Yang1,Pengjuan Xu1, Yongling Xie, Zhigui Li, Jing Xu, Tao Zhang, Zhuo Yang. Developmental Changes of BKCaChannel Depend on the Differentiation Status in Cultured Podocytes, In Vitro Cell Dev-AN ,49:205-211,2013. SCI, IF=1.312 (共同一作)
6. Pengjuan Xu, Zhigui Li, Xiaochen Zhang, Zhuo Yang，Increased response to oxidative stress challenge of nano copper induced apoptosis in mesangial cells. Journal of Nanoparticle Research(2014). DOI: 10.1007/s11051-014-2777-4.SCI, IF=2.278.
7. 许蓬娟;花春艳;艾洪滨;崔希云.石榴皮水提物的镇痛实验研究.生物医学工程研究, 2009 ,28 4 :263～266.
8. Jing Xu,Pengjuan Xu,Zhigui Li, Jie Huang, Zhuo Yang. Oxidative stress and apoptosis induced by hydroxyapatite nanoparticles in C6 cells. Journal of Biomedical Materials Research A, 2012:100A:738-745. SCI, IF=3.044
9. Xu J,Xu Pengjuan,Li Z, Xiao L, Yang Z. The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil. Cell Mol Biol Lett.2013. 18(4):494-506. SCI, IF=1.782
10. Jing Xu, Zhigui Li,Pengjuan Xu, Zhuo Yang. Protective effects of leukemia inhibitory factor against oxidative stress during high glucose-induced apoptosis in podocytes. Cell stress and Chaperones, 2012, 17:485. SCI, IF= 3.162
11. Xu, Jing; Li, Zhigui;Xu, Pengjuan; Xiao, Lu; *Yang, Zhuo. Nanosized copper oxide induces apoptosis through oxidative stress in podocytes. Archives of Toxicology.2013, 87(6):1067-1073. SCI, IF=5.078
12. Lu Xiao, Zhanyong Li,Pengjuan Xu,Zhigui Li, Jing Xu, Zhuo Yang. The expression of EPOR in renal cortex during postnatal developement. PLoS ONE, 2012, 7(7):e41993. SCI, IF=4.092
13. Li Zhigui, Xu Jing,Xu Pengjuan,Liu Shichang, Yang Zhuo. Wnt/β-catenin signaling pathway mediates high glucose induced cell injury through activation of TRPC6 in podocytes. Cell Proliferation 2013; 46(1):76-85. SCI, IF=3.28
14. 李战永，刘仕昌，许蓬娟，杨卓，张涛. 硫化氢促进大鼠恶性胶质瘤的生长.中华肿瘤杂志, 2012，34(4): 254-258. 中文核心
15. Pengjuan Xu,Zhuo Yang. Changes of TRPC 6 and BKCa Channels in Undifferentiated and Differentiated Cultured Podocytes. 《2012年美国肾脏病年会（2012 Kidney Week）论文集》，[PUB 320].
16. 许蓬娟,刘晓真,孙海基,艾洪滨. 损毁大鼠下丘脑腹内侧核对束缚-浸水应激状态延髓Fos表达及胃酸分泌的影响. 《中国生理学会第23届全国会员代表大会暨生理学学术大会论文摘要文集》2010.