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柴欣
2023-05-13 18:43
  • 柴欣
  • 柴欣 - 副研究员 硕士生导师-天津中医药大学-中医药研究院-个人资料

近期热点

资料介绍

个人简历


2001年-2005年,天津大学,药学院,药学专业学士
2005年-2007年,天津大学,药学院,生药学专业硕士
2007年-2010年,天津大学,药学院,应用化学专业博士
2010年-2013年,天津中医药大学,中药学博士后
2013年-今,天津中医药大学,副研究员
目前正在进行的科研项目包括:基于整合组学技术的血府逐瘀汤从“菌”论治的生物学基础研究,基于“量-稳-活”多维网络模式的血府逐瘀胶囊“质控markers”的辨析研究,苦乐果的化学成分研究等。
2005年至今一直从事药用植物的化学成分分离与结构鉴定、生物活性成分筛选、中药质量控制的研究。主持和参与了国家自然科学基金、国家重大新药创制科技重大专项、天津市科技计划项目、国家国际合作项目等重大科研项目;以第一作者或通讯作者发表SCI论文13篇,中文核心期刊论文7篇;以第一发明人申请专利3项,参与申请专利6项。以第11完成人参加课题《基于雌激素样作用的中药物质基础及作用机理差异性研究》,并获得了教育部颁发的科技成果以及科学技术进步一等奖。

研究领域


中药药效物质基础及中药质量控制

近期论文


(1) Yuan-Yuan Li, Long Yang, Xin Chai*, Jun-Jun Yang, Yue-Fei Wang*, Yan Zhu. Four major urinary metabolites of liquiritigenin in rats and their anti-platelet aggregation activity. Chemistry of Natural Compounds 2018, 54(3): 443-446
(2) Hui-Juan Yu#, Jing Yang#*, Jia-Min Ding, Ying He, Zhen-Zuo Jiang, Xin Chai*, Yue-Fei Wang. Stability study and identification of degradation products of caffeoylgluconic acid derivatives from Fructus Euodiae. Molecules 2018, 23, 1975
(3) Cong-Cong Li, Teng-Long Wang, Zhong-Qun Zhang, Wen-Qiang Yang, Yue-Fei Wang, Xin Chai*, Chun-Hua Wang*, Zheng Li. Phytochemical and pharmacological studies on the genus Psoralea: a mini review. Evidence-Based Complementary and Alternative Medicine 2016, 8108643: 1-17
(4) Xin Chai#*, Long-Fei Du#, Jing Yang, Zhen-Zuo Jiang, Long Yang, Yue-Fei Wang, Yan Zhu. Simultaneous determination of eight constituents in fruits of Rubus chingii by UPLC. Chinese Herbal Medicines 2016, 8(3): 280-285
(5) Jie Li#, Long-Fei Du#, Ying He, Long Yang, Yuan-Yuan Li, Yue-Fei Wang, Xin Chai*, Yan Zhu, Xiu-Mei Gao. Chemical constituents and biological activities of plants from the genus Rubus. Chemistry & Biodiversity 2015, 12: 1809-1847
(6) Ying He, Jie Li, Hong-Hua Wu, Xin Chai*, Jing Yang*, Yue-Fei Wang, Peng Zhang, Yan Zhu, Xiu-Mei Gao. A new caffeoylgluconic acid derivative from the nearly ripe fruits of Evodia rutaecarpa. Natural Product Research 2015, 29(13): 1243-1248
(7) Xiao-Long Zhang, Jie Sun, Hong-Hua Wu, Ya-Kun Jing, Xin Chai*, Yue-Fei Wang. A new indoloquinazoline alkaloidal glucoside from the nearly ripe fruits of Evodia rutaecarpa. Natural Product Research 2013, 27(20): 1917-1921
(8) Xin Chai, Shan-Shan Li, Lin Zhu, Yue-Fei Wang, Xiu-Mei Gao*. Chemical constituents of the roots of Trichosanthes kirilowii. Chemistry of Natural Compounds 2014, 50(5): 965-967
(9) Xin Chai, Yan-Fang Su*, Shi-Lun Yan, Xiong Huang. Chemical constituents of the roots of Triosteum pinnatifidum. Chemistry of Natural Compounds 2014, 50(6): 1149-1152
(10) Xin Chai, Yue-Fei Wang*, Yan-Fang Su, Abdulai J. Bah, Li-Min Hu, Yue Gao, Xiu-Mei Gao*. A rapid ultra performance liquid chromatography-tandem mass spectrometric method for the qualitative and quantitative analysis of ten compounds in Eucommia ulmodies Oliv. Journal of Pharmaceutical and Biomedical Analysis 2012, 57: 52-61
(11) Xin Chai, Yan-Fang Su*, Jun Zhang, Shi-Lun Yan, Yan-Hong Gao, Xiu-Mei Gao. A new triterpene and phenolic compounds from the roots of Pteroxygonum giraldii. Helvetica Chimica Acta 2012, 95(1): 127-133

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