个人简历

教育背景
2003年7月 河北科技大学，化工学院，制药工程专业，工学学士学位
2006年7月 陕西中医药大学，药学院，中药学专业，医学硕士学位
北京大学医学部，药学院，天然药物学专业，联合培养硕士研究生(2004年8月—2006年5月)
2011年9月 日本富山大学，医学药学教育部，生药学专业，药学博士学位

工作经历
2013年11月—今 讲师，天津医科大学
2011年11月—2013年10月 博士后研究员，香港浸会大学
2006年7月—2008年9月 研究员，以岭医药集团北京以岭医药研究院

研究领域

1.中药及天然药物中糖类药效物质的研究及其在抗病毒、抗肿瘤及机体免疫调节方面的功能评价
2.基于药食两用植物的功能食品的研究开发
3.基于糖类成分的中药及天然药物的质量控制

近期论文

1. Cai-Xia Dong*, Wensheng Zhang, Qi-Li Sun , Yun-Jia Jiang, Zheng Fu, Ying Zhang, Juan Du, Yuanxia Sun, Ning Tao*, Zhi Yao*. Structural characterization of a pectin-type polysaccharide from Curcuma kwangsiensis and its effects on reversing MDSC-mediated T cell suppression..Int J Biol Macromol. 2018,115:1233-1240. (IF: 3.929) PMID: 29723620 DOI: 10.1016/j.ijbiomac.2018.04.153
2. Cai-Xia Dong*, Liu Liu, Chang-Ying Wang, Zheng Fu, Ying Zhang, Xuan Hou, Chao Peng, Rui-Xue Ran, Zhi Yao*. Structural characterization of polysaccharides from Saposhnikovia divaricata and their antagonistic effects against the immunosuppression by the culture supernatants of melanoma cells on RAW264.7 macrophages. Int J Biol Macromol. 2018, 113, 748-756. (IF: 3.929) PMID: 29518443 DOI: 10.1016/j.ijbiomac.2018.03.022
3. Zhuo-Er Chen, Reziyamu Wufuer, Jin-Hu Ji, Jin-Fang Li, Yu-Feng Cheng, Cai-Xia Dong*, Hailiqian Taoerdahong*. Structural characterization and immunostimulatory activity of polysaccharides from Brassica rapa L.. J Agric Food Chem. 2017. 65(44): 9685-9692. (SCI, IF: 3.504)
4. Cai-Xia Dong*, Li-Jiao Zhang, Rong Xu, Gong Zhang, Ying-Biao Zhou, Xiao-Qiang Han, Ying Zhang, Yuan-Xia Sun*, Structural Characterization and Immunostimulating Activities of a Levan-type Fructan from Curcuma kwangsiensis. Int J Biol Macromol. 2015, 77, 99-104. (SCI, 5-Year IF: 3.929)
5. Jing Xu, Dan Chen, Chang Liu, Xiong-Zhi Wu, Cai-Xia Dong*, Jing Zhou*, Structural Characterization and Anti-tumor Effects of an Inulin-type Fructan Isolated from Atractylodes chinensis. Int J Biol Macromol. 2016, 82, 765-771. (SCI,5-Year IF: 3.929)
6. Cai-Xia Dong, Kyoko Hayashi, Yusuke Mizukoshi, Jung-Bum Lee, Toshimitsu Hayashi. Structures of pectic polysaccharides from Basella rubra L. and their antiviral effects. Carbohydr polym. 2011,84 (3):1084-1092. (SCI, IF: 5.158)
7. Cai-Xia Dong, Kyoko Hayashi, Yusuke Mizukoshi, Jung-Bum Lee, Toshimitsu Hayashi. Characterization of structures and anti-herpetic effects of neutral polysaccharides from Basella rubra L. Int J Biol Macromol. 2012,50 (1): 245-249. (SCI, IF: 3.929)
8. Cai-Xia Dong, Kyoko Hayashi, Jung-Bum Lee and Toshimitsu Hayashi. Characterization of structures and antiviral effects of polysaccharides from Portulaca oleracea L., Chem & Pharm Bulletin. 2010,58(4): 507-510. (SCI, IF: 1.698)
9.Longhai Dai, Can Liu, Jiao Li, Caixia Dong, Jiangang Yang, Zhubo Dai, Xueli Zhang, Yuanxia Sun*. One-Pot Synthesis of Ginsenoside Rh2 and bioactive unnatural ginsenoside by coupling promiscuous glycosyltransferase from Bacillus subtilis 168 to sucrose synthase, J Agric Food Chem. 2018, 66(11):2830-2837. (5-Year IF: 3.504) PMID: 29484884 DOI: 10.1021/acs.jafc.8b00597
10.Jiangang Yang, Yueming Zhu, Ge Qu, Yan Zeng, Chaoyu Tian, Caixia Dong, Yan Men, Longhai Dai, Zhoutong Sun*, Yuanxia Sun, Yanhe Ma*. Biosynthesis of dendroketose from different carbon sources using in vitro and in vivo metabolic engineering strategies. Biotechnol Biofuels. 2018; 11: 290. (IF: 5.497) PMID: 30386427 PMCID: PMC6202814 DOI: 10.1186/s13068-018-1293-7.
11.Longhai Dai, Jiao Li, Jiangang Yang, Yueming Zhu, Yan Men, Yan Zeng, Yi Cai, Caixia Dong, Zhubo Dai, Xueli Zhang*, Yuanxia Sun*. Use of a Promiscuous Glycosyltransferase from Bacillus subtilis 168 for the Enzymatic Synthesis of Novel Protopanaxatriol-Type Ginsenosides. J Agric Food Chem. 2018, 66(4):943-949. (SCI, 5-Year IF: 3.504)
12.Yingbiao Zhou, Yueming Zhu, Yan Men, Caixia Dong, Yuanxia Sun*, Juankun Zhang*. ConstructionofengineeredSaccharomycescerevisiaestraintoimprovethatwhole-cell biocatalytic production of melibiose from raffinose. J Ind Microbiol. 2017.44(3):489-501. (SCI, IF: 2.870)
13.Jitao Li, Jiangang Yang, Yan Men, Yan Zeng, Yueming Zhu, Caixia Dong, Yuanxia Sun, Yanhe Ma, Biosynthesis of 2-deoxysugars using whole-cell catalyst expressing 2-deoxy-D-ribose 5-phosphate aldolase. Appl Microbiol Biotechnol. 2015, 99 (19): 7963-7972. (SCI, IF: 3.337)
14.Gopinath C. B. Subash, Kyoko Hayashi, Jung-Bum Lee, Tomoko Kamori, Cai-Xia Dong, Toshimitsu Hayashi. Analysis of compounds that interfere with herpes simplex virus-host receptor interactions using surface plasmon resonance. Anal Chem. 2013, 85(21):10455-10462. (SCI, IF: 5.695)
15.Quan-Bin Han, Wai-Lun Tang, Cai-Xia Dong, Hong-Xi Xu, Zhi-Hong Jiang. An interesting two-phase solvent system and its use in preparative isolation of aconitines from aconite roots by counter-currentchromatography. J Sep Sci. 2013, 36(7):1304-1310. (SCI, IF: 2.733)
16.Xiao-Qiang Han, Gar-Lee Yue., Rui-Qi Yue, Cai-Xia Dong, Chung-Lap Chan, Chun-Hay Ko, Wing Shing Cheung1, Ke-Wang Luo1, Hui Dai, Chun-Kwok Wong, Ping-Chung Leung, Quan-Bin Han. Structure Elucidation and Immunomodulatory Activity of A Beta Glucan from the Fruiting Bodies of Ganoderma sinense. Plos One. 2014 9(7):1-10. (SCI, IF: 3.73)
17.Xiao-Qiang Han, Ben Chung Lap Chan, Cai-Xia Dong, Yin-Hua Yang, Chun-Hay Ko, et al. Isolation, structure characterization, and immunomodulating Activity of a hyperbranched polysaccharide from the fruiting bodies of Ganoderma sinense. J Agric Food Chem. 2012, 60(17): 4267-4281. (SCI, IF: 2.823)
18.Xiao-qiang Han, Ben Chung Lap Chan, Hua Yu, Yin-Hua Yang, Shui-Qing Hu, Chun-Hay Ko, Cai-xia Dong, et al. Structural characterization and immunomodulating activities of a polysaccharide from Ganoderma sinense. Int J Biol Macromol. 2012, 51, 597-603. (SCI,5-Year IF: 3.929)
19.Cai-Xia Dong, She-Po Shi, Ming-Bo Zhao, Peng-Fei Tu. A new glucopyranosyl naphthalene from Clematis hexapetala Pall. Chinese Journal of Natural Medicines. 6(1): 0023-0025, 2008. (SCI, IF: 1.114)
20. Cai-Xia Dong, She-Po Shi, Ke-Si Wu, Peng-Fei Tu. Chemical constituents from the roots andrhizomes of Clematis hexapetala Pall. Zeitschrift für Naturforschung B-Chemical Sciences. 2007,62b(6): 854-858. (SCI, IF: 0.772)
1. Pharmacon (ISSN: 1411-4283) 杂志编委（Editorial Board）
2. Carbohydrate Polymers, Journal of Agricultural and Food Chemistry, Food and Chemical Toxicology, International Journal of Biological Macromolecules, Process Biochemistry, Biomedicine & Pharmacotherapy等杂志审稿人
3. 中国民族医药学会药用资源分会常务理事
4. 世界中医药联合会中医药免疫专业委员会会员