个人简历

教育背景
1984.9-1988.7 天津医科大学药学院（理学士）
1994.4-1997.3 日本国立德岛大学药学研究科硕士课程毕业(硕士学位)
1997.4-2000.3 日本国立德岛大学药学研究科博士课程毕业(博士学位)

工作经历
1988.8-1994.3 天津市医药科学研究所
2000.4-2001.7 日本国立德岛大学药学部博士研究员
2001.8-2003.12 天津大学药物科学与技术学院中药系副主任，教授博士生导师
2004.1-至今 天津医科大学药学院 副院长，教授，博士生导师
2015.4 天津医科大学药学院 常务副院长
荣誉奖励
2004年天津市特聘教授
2005年教育部新世纪优秀人才
2007年全国优秀教师
2009年天津市优秀留学回国人员
2009年天津市五一劳动奖章先进个人
2012年天津市学科领军人才
2015年天津市教学团队-天然药物化学教学团队负责人

研究领域

中药现代质量控制研究；抗肿瘤抗糖尿病天然先导化合物的衍生合成、分子作用机制及靶点研究

近期论文

1. AMPK/AS160 mediates tiliroside derivatives-stimulated GLUT4 translocation in muscle cells, Chang Zhang，Jia Liu, Meina Jin,, Nan Qin, Ying Chen, Wenyan Niu*, Hongquan Duan*, Drug Design, Development and Therapy 2018,12, 1581-1587.
2. The synthesis and anti-metastatic effects of optical isomers of ionone alkaloid 9-(N,N-dimethyl)- 4,7- megastig- medien-3-one, Xiao-Ran Wu, Wen Zhu, Hong-Zheng Fu, Hong-Quan Duan*, Nan Qin*, Fitoterapia. 2018,127:1-6.
3. Flavonoid derivative (Fla-CN) inhibited adipocyte differentiation via activating AMPK and up-regulating microRNA-27 in 3T3-L1 cells，Chun-Chun Gan, Tian-Wen Ni, Yang Yu, Nan Qin, Ying Chen, Mei-Na Jin*, Hong-Quan Duan*，European Journal of Pharmacology，2017, 797:45–52.
4. Synthesis and anti-inflammatory activities of 1-O-acetylbritannilactone analogues Xiao-Peng Wei, Yu-Fen Chen, Hong Zhu, Xiao-Ran Wu, Yang Yu, De-Xin Kong, Hong-Quan Duan,*, Mei-Hua Jin,**, Nan Qinc,**，Phytochemistry Letters 2017, 19:248–253.
5. Qin N*, Jia M, Wu XR, Shou XA, Liu Q, Gan CC, Jin MN, Yu Y, Duan HQ*. Synthesis and anti-metastatic effects of pregn-17(20)-en-3-amine derivatives. Eur J Med Chem. 2016, 26;124:490-499.
6. Qin N, Chen Y, Jin MN, Zhang C, Qiao W, Yue XL, Duan HQ*, Niu WY. Anti-obesity and anti-diabetic effects of flavonoid derivative (Fla-CN) via microRNA in high fat diet induced obesity mice. Eur J Pharm Sci. 2016, 20(82):52-63.
7. Xiang-Yu Li, Yang Yu, Miao Jia, Mei-Na Jin, Qin N, Chuan Zhao* and Hong-Quan Duan*, Terminamines K–S, Antimetastatic Pregnane Alkaloids from the Whole Herb of Pachysandra terminalis, Molecules 2016, 21, 1283.
8. Synthesis and anti-metastatic effects of novel chiral ionone alkaloid derivatives, Hai-Jun Fang, Xiao-Ai Shou, Qian Liu, Chun-Chun Gan, Hong-Quan Duan,* Nan Qin**, European Journal of Medicinal Chemistry 101 (2015) 245-253.
9. Zhao C.; Gu Q.; Xu W.-G.; Xing G.-S.; Jin D.-J.; Xu R.; Li H.; Duan H.-Q.; Zhou J.; Tang S.-A.，Three new polyunsaturated lipids from a Guangxi marine sponge Haliclona sp.，Journal of Asian Natural Products Research, 2015，17(2), 114-119.
10. Mei-Na Jin, Sheng-Nan Ma, Hui-Yuan Zhai, Nan-Qin, Hong-Quan Duan* and De-Xin Kong*, A NEW MEGASTIGMANE ALKALOID FROM Pachysandra terminalis WITH ANTITUMOR METASTASIS EFFECT, Chemistry of Natural Compounds, 2015, 51(2), 311-315.
11. Chen Y, Zhang C, Jin MN, Qin N, Qiao W, Yue XL, Duan HQ*, Niu WY*. Flavonoid derivative exerts an antidiabetic effect via AMPK activation in diet-induced obesity mice. Nat Prod Res. 2015, 29:1-5.
12. Yang Jiao, Jinbo Fang, Shengan Tang,*and Hongquan Duan*, PENANGIANOL A AND B: TWO NEW NORLIGNANS FROM RHIZOMES OF Abacopteris penangiana, Chemistry of Natural Compounds, 2015, 51(2), 232-235.
13. Min Han, Guo-Cheng Wang, Hong-Quan Duan*, Construction of supramolecular nanofibers through electrostatic interaction between perylene and cholesterol derivatives, Chinese Chemical Letters, 25(1), 2014, 51-54.
14. Sheng-An Tang, Hong Zhu, Nan Qin, Jing-Ya Jing, Eunkyung Lee, De-Xin Kong, Mei-Hua Jin*, Hong-Quan Duan*, Anti-inflammatory Terpenes from Flowers of Inula Japonica, Planta Medica, 2014, 80, 583-589.
15. Zhao C, Gan CC, Jin MN, Tang SA, Qin N, Duan HQ*, Antitumor metastasis pregnane alkaloids from Pachysandra terminalis, J Asian Nat Prod Res. 2014;16(5): 440-6.
16. Hai-Jun Fang, Qian Liu, Chun-Chun Gan, Mei-Na Jin, *Nan Qin, Hong-Quan Duan*. Synthesis and Antitumor Invasive Activity of Novel Ionone Alkaloid Derivatives，Letters in Drug Design & Discovery，2014, 11:395-402.
17. Jia Liu, Sheng-Nan Ma, Xiang Zhang, Mei-Na Jin, Mei-Hua Jin, Dexin Kong*, Nan Qin*, and Hong-Quan Duan*, SYNTHESIS AND ANTIMETASTATIC EFFECT OF E-SALIGNONE, Chemistry of Natural Compounds, Vol. 50, No. 4, September, 2014 [Russian original No. 4, July–August, 2014].
18. Wen Chen, Xiao-Ai Shou, Ying Chen, Nan Qin, Wei Qiao, Sheng-An Tang*, and Hong-Quan Duan*, A NEW AURONE FROM Smilax riparia, Chemistry of Natural Compounds, 2014,50(6), 859-862.
19. Hong-Ling Wang, Nan Qin, Jia Liu, Mei-Na Jin, Xiang Zhang, Mei-Hua Jin, Dexin Kong, Shen-De Jiang, and Hong-Quan Duan*,Synthesis and Antimetastatic Effects of E-Salignone Amide Derivatives, DRUG DEVELOPMENT RESEARCH, 2014,75(2):76-87.
20. Mei-Na Jin, Guo-Ru Shi, Sheng-An Tang, Nan-Qin , Wei Qiao, Hong-Quan Duan*, Flavonoids from Tetrastigma obtectum enhancing glucose consumption in insulin-resistance HepG2 cells via activating AMPK, Fitoterapia 2013, 90:240–246.