个人简历

石硕，男，博士，教授，博士生导师，毕业于中山大学（2007年），获化学生物学专业理学博士学位（导师：中国科学院院士，计亮年教授），2012年美国加州理工学院（California Institute of Technology, Caltech）Visiting Associate （导师：美国国家科学院，美国艺术与科学院，美国哲学院三院院士：Professor Jacqueline K. Barton）。2007 年进入同济大学化学系工作至今，历任讲师，副教授，教授，曾分别荣获同济大学青年岗位能手，同济大学优秀青年教师，同济大学骨干教师，同济大学青年教师讲课竞赛最佳教学内容、方法、手段奖，同济大学青年教师讲课竞赛最佳教学设计奖，同济大学本科生学科竞赛优秀指导老师，同济大学巴斯夫优秀科技论文奖指导老师等荣誉。

研究领域

"""""(1) 金属抗癌药物的设计合成及抗肿瘤机制研究\r
(2) 疾病基因诊断\r
(3) DNA分子器件设计"

近期论文

Ru-Ru Gao, Tian-Ming Yao*, Xiao-Yan Lv, Yan-Yan Zhu, Yi-Wei Zhang and Shuo Shi*, Integration of G-quadruplex and DNA-templated Ag NCs for Nonarithmetic Information Processing, Chemical Science, 2017, 8, 4211–4222.\r
\r
Ru-Ru Gao, Tian-Ming Yao*, Xiao-Yan Lv, Yan-Yan Zhu, Yi-Wei Zhang and Shuo Shi*, Chem. Sci., 2017, 8, 4139-4139. Front Cover\r
\r
Ru-Ru Gao, Shuo Shi*, Yu-Jie Li, Maierhaba Wumaier, Xiao-Chun hu and Tian-Ming Yao*, Coordination Polymer Nanoparticles from Nucleotide and Lanthanide Ions as a Versatile Platform for Color-tunable Luminescence and Integrating Boolean Logic Operations, Nanoscale, 2017, 9, 9589-9597.\r
\r
Ao Huang, Weiwei Li, Shuo Shi* and Tianming Yao*, Quantitative Fluorescence Quenching on Antibody-conjugated Graphene Oxide as a Platform for Protein Sensing, Scientific Reports, 2017, 7, 40772. \r
\r
Ru-Ru Gao, Shuo Shi,* Ying Zhu, Hai-Liang Huang, and Tian-Ming Yao*, A RET-Supported Logic Gate Combinatorial Library to Enable Modeling and Implementation of Intelligent Logic Functions, Chemical Science, 2016, 7, 1853-1861.\r
\r
Juanjuan Li, Shuo Shi* and Tianming Yao*, Three label-free thrombin aptasensors based on aptamers and [Ru(bpy)2(o-mopip)]2+, J. Mater. Chem. B, 2016, 4, 1361–1367. (Hot Paper)\r
\r
Ying Zhu, Shuo Shi*, Ru-ru Gao, Hai-liang Huang, Yan-yan Zhu, Xiao-yan Lv, Tian-ming Yao*, Ultrasensitive and Universal Fluorescent Aptasensor for the Detection of Biomolecules (ATP, Adenosine and Thrombin) Based on DNA/Ag Nanoclusters Fluorescence Light-up System, Biosensors and Bioelectronics, 2016, 79,205-212.\r
\r
Hailiang Huang, Shuo Shi*, Xing Gao, Ruru Gao, Ying Zhu, Xuewen Wu, Ruimin Zang, and Tianming Yao*, A universal label-free fluorescent aptasensor based on Ru complex and quantum dots for adenosine, dopamine and 17β-estradiol detection, Biosensors and Bioelectronics, 2016, 79,198-204.\r
\r
XinWang, Lihong Pei, Xiumin Fan, Shuo Shi*, [Ru(L)2(3-tppp)]2+ (L=bpy, phen) stabilizes two different forms of the human telomeric G-quadruplex DNA, Inorganic Chemistry Communications, 2016, 72, 7–12.\r
\r
Shuo Shi,* Xing Gao, Junliang Yao, Hailiang Huang, Juan Zhao, and Tianming Yao, Effect of the Ancillary Ligands on the Spectral Properties and G-quadruplexes DNA Binding Behaviours: A Combined Experimental and Theoretical Study, Chem. Eur. J. 2015, 21, 13390 –13400.\r
\r
Shuo Shi*, Jin-Hong Xu, Xing Gao, Hai-Liang Huang and Tian-Ming Yao*, Binding Behaviours for Different Types of DNA G-quadruplexes: Enantiomers of [Ru(bpy)2(L)]2+ (L= dppz, dppz-idzo), Chem. Eur. J. 2015, 21, 11435–11445.\r
\r
Hailiang Huang, Shuo Shi*, Xuyue Zheng,Tianming Yao*, Sensitive detection for coralyne and mercury ions based on homo-A/T DNA by exonuclease signal amplification, Biosensors and Bioelectronics, 2015, 71, 439–444.\r
\r
Xuyue Zheng, Tianming Yao*, Shuo Shi*, Copper-modulated Silver Nanoclusters as An On-Off-On Fluorescence Probe for the Selective Detection of L-histidine, Biosensors and Bioelectronics, 2015, 66, 103-108.\r
\r
Xing Gao, Shuo Shi*, Jun-Liang Yao, Juan Zhao and Tian-Ming Yao*, Impacts of terminal modification of [Ru(phen)2dppz]2+ on the luminescence properties: a theoretical study, Dalton Trans., 2015, 44, 19264–19274. \r
\r
Xing Gao, Li Wang*, Hai-Liang Huang, Lin-Lin Wang, Jun-Liang Yao, Shuo Shi and Tian-Ming Yao*, Molecular “light switch” [Ru(phen)2dppzidzo]2+ monitoring the aggregation of tau, Analyst, 2015, 140, 7513–7517.\r
\r
Xiao-Hui Lu, Shuo Shi*, Jun-Liang Yao, Xing Gao, Hai-Liang Huang, Tian-Ming Yao*, Two structurally analogous ruthenium complexes as naked-eye and reversible molecular “light switch” for G-quadruplex DNA, Journal of Inorganic Biochemistry 140 (2014) 64–71.\r
\r
Linlin Wang, Tianming Yao*, Shuo Shi*, Yanlin Cao, Wenliang Sun A label-free fluorescent probe for Hg2+ and biothiols based on graphene oxide and Ru-complex, Scientific Reports, 2014, 4, 5320.\r
\r
Shuo Shi*, Tianming Yao*, Liangnian Ji, DNA molecular light switch and biosensors based on ruthenium(II) polypyridyl complexes, Scientia Sinica Chimica, 2014, 44 (4): 460-470.\r
\r
Yanlin Cao, Shuo Shi*, Linlin Wang, Junliang Yao and Tianming Yao*, Ultrasensitive fluorescence detection of heparin based on quantum dots and a functional ruthenium polypyridyl complex, Biosensors and Bioelectronics, 2014, 55, 174-179.\r
\r
Shuo Shi*‡, Shane Gao,‡ Tongcheng Cao, Jie liu, Xing Gao, Jian Hao, Chunyan Lv, Hailiang Huang, Jun Xu*, Tianming Yao*,Targeting Human Telomeric G-quadruplex DNA and Inhibition of Telomerase Activity with [(dmb)2Ru(obip)Ru(dmb)2]4+, PloS ONE, 2013, 8(12), e84419.