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王光伟
2023-05-13 10:59
  • 王光伟
  • 王光伟 - 研究员 博导-天津大学-分子光电科学重点实验室-个人资料

近期热点

资料介绍

个人简历


学习与工作简历: 1994.9–1998.7,兰州大学化学系, 本科生 1998.8–2003.7,中科院上海有机所金属有机化学国家重点实验室, 研究助理 2003.8–2004.7,晟康生物医药技术(上海)有限公司, 助理研究员 2004.9–2009.8,美国Purdue University化学系, 博士研究生 (导师:E. Negishi) 2009.8–2011.6,美国Purdue University化学系, 博士后 (导师:E. Negishi) 2011.7–2014.5,上海源力生物技术有限公司(江苏恒瑞医药上海工艺研发中心), 副主任、主任 2014.6 - 至今 天津大学理学院化学系

研究领域


""1. 过渡金属催化的不饱和烯烃和炔烃的碳金属化反应研究 2. 过渡金属催化的氟烷基化反应研究 3. 活性药物分子的合""""

近期论文


44. Dai,Q.; Zhao, H.; Cao, H.; Yang, J.; Zhao, W.; Wang, T.; Liu, L.; Fan, Z.; Wang, G. Photo-triggered conversion of hydrophilic fluorescent biomimetic nanostructures for cell imaging. Chem. Commun. 2018, 54, in press. DOI: 10.1039/c8cc07197g 43. Liu, J.; Wang, G. N, N, N’, N’’, N’’ -Pentamethyldiethylenetriamine. In Encyclopedia of Reagents for Organic Synthesis, Wiley, 2018, in press. 42. Zhou, S.; Yuan, F.; Guo, M.; Wang, G.; Tang, X.; Zhao, W. Switchable synthetic strategy toward trisubstituted and tetrasubstituted exocyclic alkenes. Org. Lett. 2018, 20, 6710-6714. DOI: 10.1021/acs.orglett.8b02814 41. Yuan, F.; Zhou, S.; Yang, Y.; Guo, M.; Tang, X.; Wang, G. Copper Catalyzed One-Pot Difluoroalkylation and Lactonization of Unsaturated Carboxylic Acids. Org. Chem. Front. 2018, 5, 3306-3309. DOI: 10.1039/C8QO00940F 40. Wang, X.; Liu, J.; Yu, Z.; Guo, M.; Tang, X.; Wang, G. Desulfonylation-Initiated Distal Alkenyl Migration in Copper-Catalyzed Alkenylation of Unactivated Alkenes. Org. Lett. 2018, 20, 6516-6519. DOI: 10.1021/acs.orglett.8b02840 39. Dai, Q.; Zhao, H.; Fan, Z.; Zhao, W.; Wang, G.; Zhang, J.; Hou, R.; Du, P.; Cao, H.* In Situ Nanoreactors: Controllable Photoluminescent Carbon-Rich Polymer Nanodots Derived from Fatty Acid under Photoirradiation. Macromol. Rapid Commun. 2018, 39, 1800152. DOI: 10.1002/marc.201800152 38. Feng, X.; Wang, X.; Chen, H.; Tang, X.; Guo, M.; Zhao, W.; Wang, G. Copper-Mediated Regioselective Hydrodifluoroalkylation of Alkynes. Org. Biomol. Chem., 2018, 16, 2841-2845. 10.1039/C8OB00256H 37. Wang, X.; Li, M.; Yang, Y.; Guo, M.; Tang, X.; Wang, G. One-pot Construction of Difluorinated Pyrrolizidine and Indolizidine Scaffolds via Copper-Catalyzed Radical Cascade Annulation. Adv. Synth. Cat. 2018, 360, 2151-2156. DOI: 10.1002/adsc.201701643 36. Li, Y.; Liu, J.; Zhao, S.; Du, X.; Guo, M.; Zhao, W.; Tang, X.; Wang, G. Copper-Catalyzed Fluoroolefination of Silyl Enol Ethers and Ke-tones towards the Synthesis of β-Flouroenones. Org. Lett. 2018, 20, 917?920. DOI: 10.1021/acs.orglett.7b03700 35. Wang, G.; Ma, J.-A. NFSI and its analogs electrophilic fluorination for preparing alkyl fluorides. In Fluorination. Synthetic Organofluorine Chemistry, vol. 1, Hu, J.; Umemoto, T., Eds, Springer, 2018, Chap. 6.1 (DOI: 10.1007/978-981-10-1855-8_6-1). 34. Chen, H.; Wang, X.; Guo, M.; Zhao, W.; Tang, X.; Wang, G. Highly Efficient and Versatile Synthesis of α,α-Difluoro-γ-lactams via Aminodifluoroalkylation of Alkenes. Org. Chem. Front. 2017, 4, 2403-2407. 33. Li, H.; Ren, X.; Zhao, W.; Tang, X.; Wang, G. The cross-coupling of directed C-H and organometallic reagents for C-C bond formation. Chin. J. Org. Chem. 2017, 37, 2287-2302. 32. Wang, X.; Zhao, S.; Liu, J.; Zhu, D.; Guo, M.; Tang, X.; Wang, G. Copper-Catalyzed C?H Difluoroalkylations and Perfluoroalkylations of Alkenes and (Hetero)arenes. Org. Lett. 2017, 19, 4187-4190. 31. Jing, H.; Feng, X.; Guo, M.; Zhou, S.; Li, Y.; Zhang, J.; Zhao, W.; Tang, X.; Wang, G. Copper-catalyzed regioselective formal allylboration of arylsubstituted terminal alkynes with bis(pinacolato)diboron and allyl halides/sulfonates. Asian J. Org. Chem. 2017, 6, 1375-1379. 30. Zhang, H.; Ren, X.; Zhao, W.; Tang, X.; Wang, G. One-pot Synthesis of p-Amino-substituted Unsymmetrical Benzils and Benzil Derivatives. Adv. Synth. Cat. 2017, 359, 395-401. 29. Wu, J.; Wang, D.; Chen, X.; Gui, Q.; Li, H.; Tan, Z.; Huang, G.; Wang, G. Synthesis of 4-benzylpyridines via Pd-catalyzed CH3-arylation of 4-picoline. Org. Biomol. Chem., 2017, 15, 7509–7512. 28. Chen, X.; Tan, Z.; Gui, Q.; Hu, L.; Liu, J.; Wu, J.; Wang, G. Photocatalytic/Cu-promoted C-H activations: Visible-light-induced ortho-selective perfluoroalkylation of benzamides. Chem. Eur. J. 2016, 22, 6218–6222. 27. Du, J.; Xu. G.; Lin, H.; Wang, G.; Tao, M.; Zhang, W. Highly efficient reduction of carbonyls, azides, and benzyl halides by NaBH4 in water catalyzed by PANF-immobilized quaternary ammonium salts. Green Chem. 2016, 18, 2726–2735. 26. Du, J.; Shuai, B.; Tao, M.; Wang, G.; Zhang, W. Pyrrolidine modified PANF catalyst for asymmetric Michael addition of ketones to nitrostyrenes in aqueous phase. Green Chem. 2016, 18, 2625–2631. 25. Ren, X.; Wang, G.; Tang, X.; Zhao, W. Iodine-Catalyzed One-Pot Synthesis of α-Ketoamides from Unsaturated Hydrocarbons. Chin. J. Org. Chem. 2015, 35, 1733-1738.

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