个人简历

1995 Ph. D. University of California, San Diego, CA, USA 1995 Postdoctoral Memorial Sloan-Kettering Cancer Center, NY, USA

研究领域

""The research in the group of Sorensen encompasses the areas of a) organic chemistry: rapid formation of molecular complexity in biologically active natural product synthesis, b) Innovative methods and strategies for chemical synthesis, c) Design and synthesis of candidates for antibiotic development efforts, and d) New concepts for complex synthesis featuring C–H activation methods."Our laboratory pursues ideas and chemical reactions that have the potential to advance the field of organic synthesis. The molecular architectures of physiologically active natural products inspire us to consider bold strategies for rapidly generating their intricate structures from relatively simple chemicals. We embrace risk-taking during the creative process of synthesis design and seek new ways for thinking about synthesis. """

近期论文

Siler, D. A.; Mighion, J.D.; Sorensen, E. J. An Enantiospecific Synthesis of Jiadifenolide. Angew. Chem., Int. Ed. 2014, 53, 5332. Choi, J.; Park, H.; Yoo, H. J.; Kim, S.; Sorensen, E. J.; Lee, C. Tandem Diels−Alder and Retro-Ene Reactions of 1‑Sulfenyl- and1‑Sulfonyl-1,3-dienes as a Traceless Route to Cyclohexenes. J. Am. Chem. Soc. 2014, 136, 9918. Sorensen, E. J. Organic synthesis: A biochemical messenger made easily. Nature 2012, 489, 214. Jimin K. J.; Schneekloth, J. S., Jr.; Sorensen, E. J. A chemical synthesis of 11-methoxy mitragynine pseudoindoxyl featuring the interrupted Ugi reaction. Chem. Sci. 2012, 3, 2849. Lotesta, S. D.; Liu, J.; Yates, E. V.; Krieger, I.; Sacchettini, J. C.; Freundlich, J. S.; Sorensen, E. J. Expanding the pleuromutilin class of antibiotics by de novo chemical synthesis. Chem. Sci. 2011, 2, 1258.