个人简历
Education Experience 1970-1974 Bachelor of Science Biology Loyola University, Chicago, USA 1975-1977 Bachelor of Science Pharmacy University of Illinois Medical Center, Chicago, US 1977-1981 Doctor of Philosophy Pharmacognosy University of Illinois Medical Center, Chicago, US 1981-1982 Postdoctoral Natural Products Chemistry University of Zuruich, Zurich, CH Professional Experience 2007-2013 Associate Dean for Research and Associate Professo College of Phaermacy, University of Hawaii at Hilo 2007-2007 Vice President, Botanical Science and Regulation Council for Responsible Nutrition 2001-2005 Senior Investigator Merck Research Laboratories, Dept of Natural Products Chemistry 1993-2000 Senior Research Fellow Merck Research Laboratories, Dept. of Natural Products Chemistry 1987-1993 Research Fellow Merck Research Laboratories, Dept. of Natural Products Chemistry 1983-1987 Senior Research Chemist Merck Research Laboratories, Dept. of Natural Products Chemistry 1982-1983 Assistant Professor of Pharmacogbnosy Rutgers University 1978-1980 Registered Pharmacist Meyer Drugs, Chicago 2014- Professor Tianjin university
研究领域
The research of the Borris groups involves a) Validation of traditional medical practices, b) Discovery of novel biologically active natural products, c) Natural products used as dietary supplements, d) Phytochemical systematics, e) Application of NMR spectrometry to the structure determination of natural products, and f) Applications of high performance centrifugal partition chromatography to the isolation of biologically active natural products and other organic compounds.
近期论文
Lange, I., Moschny, J., Tamanyan, K., Khutsishvili, M., Atha, D., Borris, R.P., and Koomoa, D.L. Scrophularia orientalis Extract Induces Calcium Signaling and Apoptosis in Neuroblastoma Cells. Int. J. Oncology, 2016, 48, 1608-1616. Showman, A., Baker, J.D., Linares, C., Naeole, C.K., Borris, R.P., Johnston, E., Konanui, J., and Turner, H. Contemporary Pacific and Western Perspectives on ‘Awa Toxicology. Fitoterapia, 2015, 100, 56-67. Lange, I., Moschny, J., Kerimov, V.M., Khutsishvili, M. Atha, D., Borris, R.P., and Koomoa, D.L. Juniper extracts regulate calcium signaling pathways and induce apoptosis in neuroblastoma cells. J. Pharm. Pharm.Scien. 2015, 1 (1) 1-7. Clark, B.R., Pramanick, S., Arancon, N., and Borris, R.P. Unusual Flavonoid Glycosides from the Hawaiian Tree Metrosideros polymorpha. Nat. Prod. Commun., 2015, 10 (6) 925-928. Shimoda, L.M.N., Showman, A., Baker, J.D., Lange, I., Koomoa-Lange, D., Borris, R.P., and Turner, H. Differential Regulation of Calcium Signaling Pathways by Components of Piper methysticum (‘Awa) Phytotherapy Research, 2014, 29, 582-590. Clark, B.R., Bliss, B.J., Suzuki, J.Y., and Borris, R.P. Chemotaxonomy of Hawaiian Anthurium Cultivars Based on Multivariate Analysis of Phenolic Components. J. Agric. Food Chem. 2014, 62(46) 11323-11334. Ul-Haq, I.; Youn, U.-J.; Chai, X.-Y.; Park, E. J.; Kondratyuk, T. P.; Simmons, C. J.; Borris, R. P.; Mirza, B.; Pezzuto, J. M.; Chang, L. C. Biologically active Withanolides from Withania coagulans. J. Nat. Prod. 2013, 76, 22. Youn, U.-J.; Park, E.-J.; Kondratyuk, T. P.; Simmons, C. J.;Borris, R. P.; Tanamatayarat, P.; Wongwiwatthananukit, S.; Toyama, O.; Songsak, T.; Pezzuto, J. M.; Chang, L. C. Anti-inflammatory Sesquiterpene Lactones from the Flower of Vernonia cinerea. Bioorg. Med. Chem. Lett. 2012, 22, 5559. Clark, B. R.; Suzuki, J. Y.; Bliss, B. R.; and Borris, R. P. Flavone C-glycosides from Anthurium andreanum. Nat. Prod. Commun. 2012, 7, 747. Jayasuriya, H.; Herath, K. B.; Ondeyka, J. G.; Guan, Z.; Borris, R. P.; Tiwari, S.; de Jong, W.; Chavez, F.; Moss, J.; Stevenson, D. W.; Beck, H. T.; Slattery, M.; Zamora, N.; Schulman, M.; Ali, A.; Sharma, N.; MacNaul, K.; Hayes, N.; Menke, J. G.; Singh, S. B. Diterpenoid, Steroid and Triterpenoid Agonists of Liver X Receptors from Diversified Terrestrial Plants and Marine Sources. J. Nat. Prod. 2005, 68, 1247. Herath, K.; Jayasuriya, H.; Ondeyka, J. G.; Guan, Z.; Borris, R. P.; Stijfhoorn, E.; Stevenson, D.; Wang, J.; Sharma, N.; MacNaul, K.; Menke, J. G.; Ali, A.; Schulman, M. J.; Singh, S. B. Guttiferone I, a New Prenylated Benzophenone from Garcinia humilis as a Liver X Receptor Ligand. J. Nat. Prod. 2005, 68, 617.
