个人简历

孙艳艳，副教授，硕士生导师。现任化学生物与材料工程学院化学化工系副主任，中国化学会会员。2007年获东南大学制药工程专业学士学位；2013年获东南大学制药工程专业博士学位。主讲《有机化学》、《精细化学品化学》等专业课程。主持国家自然科学基金项目1项，作为主要参与者，参与国家“重大新药创制”科技专项、多项国家自然科学基金项目、省部级科技项目。发表SCI论文30余篇(其中以第一作者及通讯作者发表SCI论文11篇)。申请发明专利并授权7项。2014年获苏州市高等院校、科研院所紧缺高层次人才引进资助，苏州科技大学优秀青年骨干教师培养对象。

研究领域

金属抗肿瘤药物的研究包括铂类药物和其它金属药物的设计、合成及筛选；有机合成药物的研发及其中间体的工艺开发；生物药物修饰剂的研究。

近期论文

1. Yanyan Sun,* Huaixin Wei, Qiang Zhang, Xin Zhao. Platinum(II) Complexes with 1,10-phenanthroline and Hydrophilic Alkoxyacetate Ligands as Potential Antitumor Agents. Chem. Biodiversity 2019, 16(1), e1800373 (Front Cover)
2. Yanyan Sun*, Jian Zhao*, Zhongling Ji. Bifunctional platinum(II) complexes with bisphosphonates substituted diamine derivatives: Synthesis and in vitro cytotoxicity. Chemistry & Biodiversity 2017, 14(12): e1700348
3. Yanyan Sun*, Xiwen Wu, Lei Chen, Li Luo. Synthesis and cytotoxicity of N,N'-dibisphosphonate ethylenediamine derivatives and platinum(II) complexes with high binding property to hydroxyapatite. Inorganica Chimica Acta 2017, 457: 46-52
4. Yanyan Sun*, Lei Chen, Xiwen Wu, Qian Ding. Bifunctional bisphosphonate derivatives and platinum complexes with high affinity for bone hydroxyapatite. Bioorganic & Medicinal Chemistry Letters 2017, 27(4): 1070-1075
5. Yanyan Sun, Zhe Cao, Shaohua Gou*, Tingting Hu. Novel oxaliplatin derivatives with 1-(substituted benzyl)azetidine-3,3-dicarboxylate anions. Synthesis, cytotoxicity, and interaction with DNA. Chemistry & Biodiversity 2014, 11(1): 115-125
6. Yanyan Sun, Gang Xu, Zhe Cao, Shaohua Gou*. Synthesis and biological evaluation of platinum(II) complexes containing (1R,2R)-N1-alkyl-1,2-diaminocyclohexane and D-(+)-camphorate ligands. Inorganica Chimica Acta 2013, 395: 154-159
7. Yanyan Sun, Fei Liu, Shaohua Gou*, Lin Cheng, Lei Fang, Runting Yin. Synthesis and in vitro antiproliferative activity of platinum(II) complexes with N-monoalkyl 1R,2R-diaminocyclohexane as ligands. European Journal of Medicinal Chemistry 2012, 55: 297–306
8. Yanyan Sun, Tingting Hu, Shaohua Gou*, Zhe Cao. Novel hydrophilic cis-bis(cyclopentylamine)platinum(II) complexes: Synthesis, characterization, antitumor activity and interaction with DNA. Inorganica Chimica Acta 2012, 391: 158-161
9. Yanyan Sun, Runting Yin, Shaohua Gou*, Jian Zhao. Antitumor platinum(II) complexes of N-monoalkyl-1R, 2R-diaminocyclohexane derivatives with alkyl groups as hindrance. Journal of Inorganic Biochemistry 2012, 112: 68-76
10. Yanyan Sun, Shaohua Gou*, Fei Liu, Runting Yin, Lei Fang. Synthesis, in vitro cytotoxicity and interaction with DNA of platinum(II) complexes with N-monocycloalkyl derivatives of 1R,2R-diaminocyclohexane as carrier ligands. ChemMedChem 2012, 7(4): 642-649
11. Yanyan Sun, Shaohua Gou*, Runting Yin, Pingyuan Jiang. Synthesis, antiproliferative activity and DNA binding study of mixed ammine/cyclohexylamine platinum(II) complexes with 1-(substituted benzyl) azetidine-3, 3-dicarboxylates. European Journal of Medicinal Chemistry 2011, 46(10): 5146-5153