个人简历

学历背景：
2001.9－2005.7 兰州大学本科
2005.9－2010.12 兰州大学博士生
工作经历：
2011.1－2012.11 上海睿智化学研究有限公司合成研究员
2012.11－至今苏州大学医学部药学院合成药化教研室讲师

研究领域

（1）抗肿瘤药物和中枢神经系统药物的设计与合成研究
（2）具有生理活性的天然产物的合成与修饰研究

近期论文

1. Zheng J., Yang Z., Li X., Li L., Ma H., Wang M., Zhang H., Zhen X., Zhang X.* Optimization of 6-Heterocyclic-2-(1H-pyrazol-1-yl)-N-(pyridin-2-yl)pyrimidin-4-amine as Potent Adenosine A2A Receptor Antagonists for the Treatment of Parkinson's Disease. ACS Chem. Neurosci., 5, 674-682, 2014.
2. Lu W., Geng D., Sun Z., Yang Z., Ma H., Zheng J., Zhang X.* Scaffold hopping approach to a new series of smoothened antagonists, Bioorg. Med. Chem. Lett., 24, 2300-2304, 2014.
3. Yang Z., Li X., Ma H., Zheng J., Zhen X., Zhang X.* Replacement of amide with bioisosteres led to a new series of potent adenosine A2A receptor antagonists. Bioorg. Med. Chem. Lett., 24(1), 152-155, 2014.
4. Li H., Zheng J., Xu S., Ma D., Zhao C., Fang B., Xie X., She X.* Rapid construction of the [6-6-6-5] tetracyclic skeleton of the daphniphyllum alkaloid Daphenylline. Chem. Asian J., 7(11), 2519-2522, 2012.
5. Zheng J., Xie X., Zhao C., He Y., Zheng H., Yang Z., She X.* Total synthesis of (-)-Przewalskin B. Org. Lett., 13(2), 173-175, 2011.
6. Zheng H., Zheng J., Yu B., Chen Q., Wang X., He Y., Yang Z., She X.* Pt-catalyzed tandem 1,2-acyloxy migration/intramolecular [3+2] cyclaoaddtion of enynyl esters. J. Am. Chem. Soc., 132(6), 1788-1789, 2010.