个人简历

学历背景：
1989.09-1994.06 哈尔滨医科大学本科
2000.09-2003.06 苏州大学医学院药理学硕士生
2004.09-2008.06 苏州大学医学部基础医学院，药理学博士生，Ph.D
工作经历：
1994.08-2000.08 江苏省苏州市平江医院，住院医师
2003.08-2006.06 苏州大学医学院基础医学系药理学教研室助教
2006.06-至 今苏州大学医学部药学院药理系教师

研究领域

（1）肿瘤侵袭作用机理及耐药性
（2）肿瘤恶性进展相关信号通路的调控及药物干预

近期论文

1. Zhang L, Zhang Y, Liu XY, Qin ZH, Yang JM. (2011). Expression of elongation factor-2 kinase contributes to anoikis resistance and invasion of human glioma cells. Acta Pharmacologica Sinica, 32: 361–367.
2. Zhang L, Gu ZL, Qin ZH, Liang ZQ. (2008). Effect of Curcumin on adhesion of platelets to BMECs in vitro. Acta Pharmacologica Sinica, 29(7):800-807.
3. Zhang L, Gu ZL, Qin ZH. (2006). Regulatory genes controlling neural stem cells differentiation into neurons. Neurosci Bull., 22(5):294-300.
4. Zhang Y, Cheng Y, Zhang L, Ren X, Huber-Keener KJ, Lee S, Yun J, Wang HG, Yang JM. (2011) Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression. Biochem Biophys Res Commun. 414(1):129-34.
5. Zhang Y, Cheng Y, Ren X, Zhang L, Yap KL, Wu H, Patel R, Liu D, Qin ZH, Shih IM, Yang JM. ( 2011) NAC1 modulates sensitivity of ovarian cancer cells to cisplatin by altering the HMGB1-mediated autophagic response. Oncogene. 2011 Jul 11. doi:10.1038/onc.2011.290.
6.Yan Cheng, Yi Zhang, Li Zhang, Xingcong Ren, Kathryn Huber-Keener, Xiaoyuan Liu,Lei Zhou, Jiangang (Jason) Liao, Heike Keihack, Li Yan, Eric Rubin, and Jin-MingYang.(2011) MK-2206, a novel allosteric inhibitor of Akt, synergizes with gefitinib against malignant glioma via modulating both autophagy and apoptosis .Molecular Cancer Therapeutics.