苗庆庆
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苗庆庆,苏州大学放射医学与防护学院教授,博士生导师,国家重大人才工程A类青年项目入选者,江苏教授,江苏省双创博士人才项目,主持国家自然科学基金青年基金,江苏省青年基金各1项。2010年获得安徽大学化学专业学士学位,2015年获得中国科学技术大学分析化学专业博士学位。2015年至2018年在新加坡南洋理工大学化学与生物医学工程学院完成博士后研究。2018年11月加入苏州大学放射医学与防护学院分子影像与核医学研究中心。主要从事发展核医学探针、光学探针、纳米技术等用于疾病诊断、治疗及精准医学等的研究。研究领域涉及分子影像,纳米医学,转化医学等交叉领域。迄今为止在Nature Biotechnology, Angewandte Chemie International Edition, Advanced Materials等国际核心学术期刊上发表研究论文30多篇。研究领域
""1. 放射性核素探针的设计、合成及其在重大疾病早期诊断、高效治疗等方面的应用基础研究:针对肿瘤高特性靶点和普适性肿瘤微环境开发高性能核素探针;通过合理调控探针的结构,亲疏水性,分子量,自组装等性能参数,调控核素探针的体内行为,提高探针诊疗效果;\r\r2. 高灵敏、高特异性探针设计及生物医学应用:针对生物蛋白酶、pH、 ROS等与生命活动相关的生物标志物设计激活光学探针,用于肿瘤等疾病的早期诊断。""""近期论文
Yuan Zhang#, Guanglin Wang#, Qing Li*, Yue Jiang, Wan Chen, Min Zhao, Gaoling Liang, Qingqing Miao*, Acidity-Activated Charge Conversion of 177Lu-labeled Nanoagent for the Enhanced Photodynamic Radionuclide Therapy of Cancer.ACS Appl. Mater. Interfaces, 2022, 14, 3875-3884.\r\rYan Zhang#,*, Shasha He#, Wan Chen, Yinghua Liu, Xuefei Zhang, Qingqing Miao*, Kanyi Pu*. Activatable Polymeric Nanoprobe for Near‐Infrared Fluorescence and Photoacoustic Imaging of T Lymphocytes. Angew. Chem. Int. Ed., 2021, 60, 5921-5927.\r\rWu Cai#, Guohua Fan#, Hui Zhou#, Lei Chen, Jianxian Ge, Baoxing Huang, Dandan Zhou, Jianfeng Zeng*, Qingqing Miao*, Chunhong Hu*. Self-Assembled Hybrid Nanocomposites for Multimodal Imaging-Guided Photothermal Therapy of Lymph Node Metastasis. W Cai, G Fan, H Zhou, L Chen, J Ge, B Huang, D Zhou, J Zeng, Q Miao. ACS Appl. Mater. Interfaces, 2020, 12, 49407-49415.\r\rQing Li#, Shenhua Li#, Shasha He, Wan Chen, Penghui Cheng, Yan Zhang, Qingqing Miao*, and Kanyi Pu*. An Activatable Polymeric Reporter for Near-Infrared Fluorescent and Photoacoustic Imaging of Invasive Cancer. Angew. Chem. Int. Ed., 2020, 59, 7018 – 7023 (Cover).\r\rQing Li, Jianfeng Zeng, Qingqing Miao* and Mingyuan Gao. Self-Illuminating Agents for Deep-Tissue Optical Imaging. Front. Bioeng. Biotechnol.2019, 7, 326.\r\rQingqing Miao, and Kanyi Pu*. Organic Semiconducting Agents for Deep‐Tissue Molecular Imaging: Second Near‐Infrared Fluorescence, Self‐Luminescence, and Photoacoustics. Adv. Mater., 2018, 30, 1801778.\r\rQingqing Miao#, David C. Yeo#, Christian Wiraja, Jianjian Zhang, Xiaoyu Ning, Chenjie Xu,* and Kanyi Pu*. Near‐Infrared Fluorescent Molecular Probe for Sensitive Imaging of Keloid. Angew. Chem. Int. Ed., 2018, 57, 1256 –1260.\r\rQingqing Miao, Chen Xie, Xu Zhen, Yan Lyu, Hongwei Duan, Xiaogang Liu, Jesse V Jokerst, and Kanyi Pu*. Molecular afterglow imaging with bright, biodegradable polymer nanoparticles. Nat. Biotechnol., 2017, 35, 1102.\r\rQingqing Miao#, Yan Lyu#, Dan Ding and Kanyi Pu*. Semiconducting oligomer nanoparticles as an activatable photoacoustic probe with amplified brightness for in vivo imaging of pH. Adv. Mater., 2016, 28, 3662-3668.\r\rQingqing Miao, and Kanyi Pu*. Emerging designs of activatable photoacoustic probes for molecular imaging. Bioconjugate Chem., 2016, 27, 2808-2823.\r\rQingqing Miao, Qing Li, Qingpan Yuan, Lingli Li, Zijuan Hai, Shuang Liu, and Gaolin Liang*. Discriminative fluorescence sensing of biothiols in vitro and in living cells.Anal. Chem., 2015, 87, 3460-3466.\r\rQingqing Miao, ZiyeWu, Zijuan Hai, Changlu Tao, Qingpan Yuan, Yadi Gong, Yafeng Guan, Jun Jiang* and Gaolin Liang*. Bipyridine hydrogel for selective and visible detection and absorption of Cd2+. Nanoscale, 2015, 7, 2797-2804.\r\rQingqing Miao, Chunying Yin, Maolin Xie, Yufeng Luo, Zijuan Hai, Qingpan Yuan, Jun Jiang and Gaolin Liang*. Gathering nanorings via Fe 2+–bipyridine coordination. Chem. Commun., 2015, 51, 11045-11047.标签: 苏州大学 医学部放射医学与防护学院
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