个人简历

学历背景：
1999.09-2003.06：辽宁师范大学，生命科学学院，获理学学士学位
2003.09-2008.12：东北师范大学，生命科学学院，获理学博士学位
国外学习研究经历：
2012.05-2014.05，多伦多大学，结构基因组中心，访问学者、博士后
2017.04-2017.09，多伦多大学，结构基因组中心，访问教授
工作经历：
2009.04-2016.06，华中师范大学，生命科学学院，讲师
2016.07-2018.10，华中师范大学，生命科学学院，副教授
2018.11-至今， 苏州大学，药学院，特聘教授，博士生导师

研究领域

疾病相关蛋白质结构与功能研究
表观遗传调控相关蛋白质的结构与功能研究
基于蛋白质结构与功能的小分子药物筛选和设计等基础和应用基础研究

近期论文

Yanli Liu, Su Qin, Tsai-Yu Chen, Ming Lei, Shilpa S. Dhar, Jolene Caifeng Ho, Aiping Dong, Peter Loppnau, Yanjun Li, Min Gyu Lee* and Jinrong Min*, Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4, Nat Commun, 2019, 10:36.
Yanli Liu, Su Qin, Ming Lei, Wolfram Tempel, Yuzhe Zhang, Peter Loppnau, Yanjun Li and Jinrong Min*, Peptide recognition by HP1 chromoshadow domains revisited: plasticity in the pseudosymmetric histone binding site of human HP1, J Biol Chem, 2017, 292(14): 5655-5664.
Renata Z. Jurkowska, Su Qin, Goran Kungulovski, Wolfram Tempel, Yanli Liu, Pavel Bashtrykov, Judith Stiefelmaier, Tomasz P. Jurkowski, Srikanth Kudithipudi, Raluca Tamas, Hong Wu, Ludmila Dombrovski, Peter Loppnau, Richard Reinhardt, Jinrong Min*, & Albert Jeltsch*, H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1, Nat Commun, 2017, 8(1): 2057.
Yanli Liu, Li Li and Jinrong Min*, Structural biology: HDAC6 finally crystal clear, Nat Chem Biol, 2016, 12(9): 660-661.
Yanli Liu, Wolfram Tempel, Qi Zhang, Xiao Liang, Peter Loppnau, Su Qin*, and Jinrong Min*, Family-wide characterization of histone binding abilities of human CW domain-containing proteins, J Biol Chem, 2016, 291(17): 9000-9013.
Yanli Liu, Johnathan Lau, Weiguo Li, Wolfram Tempel, Li Li, Aiping Dong, Ashrut Narula, Su Qin* and Jinrong Min*, Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP, Biochem J, 2016, 473(2): 179-187.
Yanli Liu* and Jinrong Min, Structure and function of histone methylation binding proteins in plants, Biochem J, 2016, 473(12): 1663-1680.
Jacob I Stuckey, Bradley M Dickson, Nancy Cheng, Yanli Liu, Jacqueline L Norris, Stephanie H Cholensky, Wolfram Tempel, Su Qin, Katherine G Huber, Cari Sagum, Karynne Black, Fengling Li, Xi-Ping Huang, Bryan L Roth, Brandi M Baughman, Guillermo Senisterra, Samantha G Pattenden, Masoud Vedadi, Peter J Brown, Mark T Bedford, Jinrong Min, Cheryl H Arrowsmith, Lindsey I James* & Stephen V Frye*, A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1, Nat Chem Biol, 2016, 12(3): 180-187.
Yanli Liu, Ke Liu, Su Qin, Chao Xu, Jinrong Min*, Epigenetic targets and drug discovery Part 1: histone methylation, Pharmacol Ther, 2014, 143(3): 275-294.
Su Qin#, Yanli Liu#, Wolfram Tempel, Mohammad S. Eram, Chuanbing Bian, Ke Liu, Guillermo Senisterra, Lissete Crombet, Masoud Vedadi & Jinrong Min*, Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1, Nat Commun, 2014, 5: 3952.