个人简历

David Kaplan，1953年3月生，理学博士，教授，博士生导师。本科1975年毕业于美国Albany大学，1979毕业于美国Syracuse大学，现任美国Tufts 大学Stern Family Endowed 终身荣誉教授，生物医学系系主任兼化学工程系教授，美国国立卫生研究院（NIH）组织工程研究中心主任，在生物材料、组织工程研究领域，尤其是丝蛋白生物材料的研究领域有很深的造诣和极高的学术地位，承担多项美国国立卫生研究院、美国自然科学基金委的多项重大科研课题。在Nature杂志发表论文4篇，在Biomaterials、Biomicromolecular、Advanced Materials、Soft Materials、Tissue Engineering等高水平学术期刊发表论文400多篇，并同时担任Biomicromolecular副主编，Advanced Materials，Biomaterials，Tissue Engineering，Soft Materials等10多种高水平学术期刊编辑。已获得美国及世界专利20余项，并创办了三家以上高科技企业。David Kaplan教授积极与中国的科研人员展开合作，已于2011年受聘苏州大学现代丝绸国家工程实验室担任讲座教授，联合建立实验室，定期回国讲学并指导科研工作。
荣誉及获奖情况
2010 波士顿New England Baptist 医院学术委员会成员
2009 北美组织工程协会常务理事
2007 美国生物材料协会 Clemson 奖金获得者
2003 美国医学和生物工程学会常务理事
2000 Biomacromolecules杂志副总编

研究领域

天然可降解大分子材料在医疗、诊断、组织工程、光学等多个领域的应用。

近期论文

1.Castro, C. R., J. Chen, B. Panilaitis, D. L. Kaplan (2009) Emulsan-alginate beads for protein adsorption. J. Biomaterials Science Polymer Education 20(4):411-426

2.Ghosh, S., M. Laha, S. Mondal, S. Sengupta, D. L. Kaplan (2009) In vitro model of mesenchymal condensation during chondrogenic development. Biomaterials 30(33): 6530-6540

3.Huang, J.; Cebe, P.; Kaplan, DL. (2009). Hierarchical assembly of collagen-like peptides in vitro – mimicking osteogenesisimperfecta. Macromolecular Rapid Communications. 30:336-344.

4.Kang, J. H., G. M. Gimble, D. L. Kaplan. (2009) In vitro 3D model for human vascularized adipose tissue. Tissue Engineering Part A. 15(8):2227-2236

5.Lawrence BD, MarchantJK, Pindrus MA, OmenettoFG, Kaplan DL. Silk film biomaterials for cornea tissue engineering. Biomaterials. 2009 Mar;30(7):1299-308.

6.Lawrence, B.; Omenetto, FG.; Kaplan, DL. (2009). Processing methods to control silk fibroin film biomaterial features. Journal of Materials Science, in press.

Lovett, M., K. Lee, A. Edwards, D. L. Kaplan (2009). Vascularization strategies for tissue engineering. Tissue Engineering Part B Reviews 15(3):353-370

7.Lu, S., X. Wang, Q. Lu, X. Hu, N. Uppal, F. G. Omenetto, D. L. Kaplan (2009) Stabilization of enzymes in silk films. Biomacromolecules 10(5):1032-1042 [

8.Motta, A., D. Maniglio, C. Migliaresi, H-J. Kim, X. Wang, X. Hu, D. L. Kaplan (2009). Silk fibroin processing and thrombogenic responses. J. Biomaterials Science Polymer Education. 20(13):1875-1897 Murphy, A., D. L. Kaplan. (2009). Biomedical applications of chemically modified silk fibroin. Journal of Materials Chemistry, 19(36):6443-6450

9.Numata, K., B. Subramanian, H. A. Currie, D. L. Kaplan (2009). Bioengineered silk protein-based gene delivery systems. Biomaterials. 30(29):5775-5784

10.Qin, G., S. Lapidot, K. Numata, X. Hu, S. Meirovitch, M. Dekel, I. Podoler, O. Shoseyov, D. L. Kaplan (2009) Expression,crosslinking and characterization of recombinant chitin binding resilin. Biomacromolecules 10(12):3227-3234

11.Rabotyagova, OS.;Cebe, P.; Kaplan, DL. (2009). Self-assembly of genetically engineered spider silk block copolymers. Biomacromolecules, 10(2):229-236

12.Seda, Tigli R, S. Ghosh, M. Laha, N. K. Shevde, L. Daheron, J. Gimble, M. Gumusderelioglu, D. L. Kaplan (2009) Comparative chondrogenesis of human cell sources on 3D scaffolds. J. Tissue Engineering and Regenerative Medicine 3(5):348-360

13.Sundelacruz, S., D. L. Kaplan (2009) Stem cell and scaffold based tissue engineering approaches to osteochondral regenerative medicine. Seminars Cell and Developmental Biology 20(6):646-655

14.Sundelacruz, S., M. Levin, D. L. Kaplan. (2009) Role of membrane potential in the regulation of cell proliferation and differentiation. Stem Cell Review. 5(3):231-246

15.Wang, X., X. Zhang, L. Sun, B. Subramanian, M. V. Maffini, A. Soto, C. Sonnenschein, D. L. Kaplan (2009) Preadipocytes stimulate ductal morphogenesis and functional differentiation of human mammary epithelial cells on 3D silk scaffolds. Tissue Engineering Part A 15(10):3087-3098

16.Wang, X., T. Yucel, Q. Lu, X. Hu, D. L. Kaplan. 2009. Silk nanospheres and microspheres from silk/PVA blend films for drug delivery. Biomaterials 31(6):1025-1035

17.Wang, X, E. Wenk, X. Zhang, L. Meinel, G. Vunjak-Novakovic, D. L. Kaplan (2009) Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. J. Controlled Release 134(2):81-90

18.Yucel, T., N. Kojic, G. G. Leisk, T. J. Lo, D. L. Kaplan (2009) Non-equilibrium silk fibroin adhesives. Journal Structural Biology Dec 21 Epub ahead of print

19.Yucel, T., P. Cebe, D. L. Kaplan (2009) Vortex induced injectable silk fibroin hydrogels. Biophysical Journal 97(7):2044-2050

20.Zhang, X., M. R. Reagan, D. L. Kaplan (2009) Electrospun silk biomaterial scaffolds for regenerative medicine. Advance Drug Delivery Reviews 61(12):988-1006

21.Zhang, X., X. Wang, V. Keshav, X. Wang, J. T. Johanas, G. G. Leisk, D. L. Kaplan (2009) Dynamic culture conditions to generate silk-based tissue engineered vascular grafts. Biomaterials 30(19): 3213-3223