个人简历

学习工作经历
1996－2000 四川大学，获理学学士学位
2000－2005 中科院上海药物研究所，获理学博士学位
2005－2010 美国堪萨斯大学医学中心，博士后
2011－现在 苏州大学医学部药学院，副教授

研究领域

1. 药物转运蛋白结构和功能的研究
2. 药物代谢动力学研究

近期论文

1. Bian J, Jin M, Yue M, Wang M, Zhang H, Gui C. Tryptophan Residue Located at the Middle of Putative Transmembrane Domain 11 Is Critical for the Function of Organic Anion Transporting Polypeptide 2B1. Mol Pharm.2016, 13: 3553-3563.
2. Wen F, Shi M, Bian J, Zhang H, Gui C. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol. 2015, 10: 1-10.
3. Shi M, Liu Y, Bian J, Jin M, Gui C. The interactions between natural products and OATP1B1. Acta Pharmaceutica Sinica 2015, 50: 848-853.
4. Gui C, Obaidat A, Chaguturu R, Hagenbuch B. Development of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3. Curr. Chem. Genomics 2010, 4: 1-8.
5.. Gui C, Hagenbuch B. Cloning/characterization of the canine organic anion transporting polypeptide 1b4 (Oatp1b4) and classification of the canine OATP/SLCO members. Comp. Biochem. Physiol. 2010, 151: 393-399.
6. Gui C, Hagenbuch B. Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1. Protein Sci. 2009, 18: 2298-2306.
7. Gui C, Wahlgren B, Lushington GH, Hagenbuch B. Identification, Ki determination and CoMFA analysis of nuclear receptor ligands as competitive inhibitors of OATP1B1-mediated estradiol-17β-glucuronide transport. Pharmacol. Res. 2009, 60: 50-56.
8. Gui C, Hagenbuch B. Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport. Biochemistry 2008, 47: 9090-9097.
9. Gui C, Miao Y, Thompson L, Wahlgren B, Mock M, Stieger B, Hagenbuch B. Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3. Eur. J. Pharmacol. 2008, 584: 57-65.