个人简历

教育背景：\r
2006-2012年 德国奥斯纳布吕克大学(Osnabrück)和明斯特大学(Münster)纳米技术中心 理学博士\r
2001-2004年 中科院兰州化学物理研究所 理学硕士\r
1997-2001年 南昌大学 理学学士\r
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工作经历：\r
2012-2016年 耶鲁大学 博士后\r
2004-2006年 中科院上海有机化学研究所 研究助理

研究领域

""""" 非天然核酸：DNA碱基的化学修饰和功能团化\r
DNA荧光标记\r
DNA纳米自组装\r
Ｇ-四链和 i-Motif 高级结构的性能研究\r
AIE-DNA和DNA-polymer等水凝胶的制备及其应用\r
定位装载非天然氨基酸和蛋白翻译后修饰: 赖氨酸的乙酰化、甲基化; 丝氨酸/苏氨酸/酪氨酸及其类似物的磷酸化等"

近期论文

H. Xiong, N. Reynolds, C. Fan, M. Englert, D. Hoyer, S. Miller and D. Söll*, Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme. Angew. Chem. Int. Ed. 2016, 55, 4083-4086.\r
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C. Fan*, H. Xiong, N. Reynolds and D. Söll*, Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids. Nucleic Acid Research. 2015, 43(22): e156\r
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H. Xiong and F. Seela*, Cross-Linked DNA: Site Selective “Click” Ligation in Duplexes with Bis-Azides and Stability Changes Caused by Internal Cross-Links. Bioconjugate Chem., 2012, 23, 1230-1243.\r
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H. Xiong, P. Leonard and F. Seela*, Construction and Assembly of Branched Y-shaped DNA: “Click” Chemistry Performed on Dendronized 8-Aza-7-deazaguanine Oligonucleotides. Bioconjugate Chem., 2012, 23, 856-870.\r
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H. Xiong and F. Seela*, Stepwise “Click” Chemistry for the Template Independent Construction of a Broad Variety of Cross-linked Oligonucleotides: Influence of Linker Length, Position and Linking Number on DNA Duplex Stability. J. Org. Chem., 2011, 76, 5584-5597.\r
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G. Qing, H. Xiong (Co-first authors), F. Seela*a and T. Sun*b, Spatially Controlled DNA Nano-patterns by “Click” Chemistry Using Oligonucleotides with Different Anchoring Sites. J. Am. Chem. Soc., 2010, 132, 15228-15232.\r
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F. Seela*, H. Xiong and S. Budow, Synthesis and “Double Click” Density Functionalization of 8-Aza-7-deazaguanine DNA Bearing Branched Side Chains with Terminal Triple Bonds. Tetrahedron, 2010, 66, 3930-3943.\r
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F. Seela*, H. Xiong, P. Leonard and S. Budow, 8-Aza-7-deazaguanine Nucleosides and Oligonucleotides with Octadiynyl Side Chains: Synthesis, Functionalization by the Azide-Alkyne ‘Click’ Reaction and Nucleobase Specific Fluorescence Quenching of Coumarin Dye Conjugates. Org. Biomol. Chem., 2009, 7, 1374-1387.\r
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Q. Yang, S. Ma*, J. Li, F. Xiao* and H. Xiong, A water-compatible, highly active and reusable PEG-coated mesoporous silica-supported palladium complex and its application in Suzuki coupling reactions. Chem. Commun., 2006, 2495-2497.\r
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H. Xiong, F. Shi, J. Peng and Y. Deng*, Synthesis of supported gold catalysts for selective oxidation of cyclohexane with air. Chin. J. Mol. Catal., 2005, 19(3), 204-207.\r
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H. Xiong, F. Shi and Y. Deng*, Synthesis and application of supported cobalt catalyst for selective oxidation of cyclohexane and toluene. Chin. J. Catal., 2004, 25(11), 887-891.\r
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F. Shi, H. Xiong, Y. Gu, S. Guo and Y. Deng*, The first non-acid catalytic synthesis of tert-butyl ether from tert-butyl alcohol using ionic liquid as dehydrator. Chem. Commun., 2003, 1054-1055.