个人简历

2020/04 -至今，深圳大学，化学与环境工程学院，副教授\r
2016/08 - 2020/01，美国南佛罗里达大学，化学学院，博士后研究员\r
2016/04 - 2016/08，美国德克萨斯州立大学，化学与生物化学学院，博士后研究\r
2015/01 - 2016/03，日本北海道大学，触媒科学研究所，博士后研究员\r
2009/09 - 2015/01，北京大学，化学与分子工程学院，硕博连读，获理学博士学位\r
2005/09 - 2009/06，北京大学，化学与分子工程学院，本科，获学士学位

研究领域

"""""本课题组的研究集中于利用多步有机合成反应构建新颖的多臂配体，用于精准构筑结构精妙、功能先进的配位超分子、超分子聚集体及高分子材料。\r
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通过多步有机化学反应合成多臂配体，用于构筑结构新颖的配位超分子\r
利用配位驱动自组装方法构筑结构新颖、复杂程度高的超分子化合物是超分子化学的重要研究目标之一，其成功实施有利于在分子尺度上精确地构筑新型功能材料。如何通过可控的组装高效地、精准地构筑结构稳定的超分子，如何利用先进的表征手段对其结构进行有效表征是超分子基础研究领域的主要挑战。本课题通过多步的有机合成高效制备多臂配体，基于多重配位键自组装策略以及创新的合成方法（例如配体合成-自组装一锅法），构筑更多结构新颖、复杂程度高的配位超分子化合物。结合多维度质谱、核磁和扫描隧道显微镜表征，我们得以从多维度掌握超分子的结构信息。\r
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配位超分子在基底和溶液中的分级自组装行为及其应用研究\r
生物大分子（包括蛋白质、核酸、糖类等）丰富的分级自组装行为是生命功能化简为繁的重要基础，利用类似的物理化学原理，精准控制配位超分子进行分级自组装能提升超分子结构和功能上的维度，最终实现其在能源、催化、医药等领域的重要应用。该课题以配位超分子在基底和溶液中的分级自组装行为研究为起点，利用AFM/STM/TEM等成像手段深入了解其机理，并逐步开展分级组装体作为纳米导线、纳米反应器、跨（细胞膜）离子传输通道等方面的应用。 \r
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配位超分子在生物、医药领域的应用研究\r
前期合成的同轴环状超分子对革兰氏阳性细菌具有高选择性抑制效果，抗菌机理研究显示携带正电荷的刚性二维超分子选择性地聚集在带负电荷的MRSA表面，在细胞膜上有序堆积形成跨膜离子通道

近期论文

Su, F.; Zhang, S.; Chen, Z.; Zhang, Z.; Li, Z.; Lu, S.; Zhang, M.; Fang, F.; Kang, S.; Guo, C.; Su, C.; Yu, X.; Wang, H.;* Li X.* Precise Synthesis of Concentric Ring, Helicoid, and Ladder Metallo-Polymers with Chevron-Shaped Monomers. J. Am. Chem. Soc., 2022, 144, DOI: 10.1021/jacs.2c06251\r
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Xu, C.; Lin, Q.; Shan, C.; Han, X.; Wang, H.; Wang, H.;* Zhang, W.; Chen, Z.; Guo, C.; Xie, Y.; Yu, X.; Song, B.; Song, H.; Wojtas, L.; Li, X.* Metallo-supramolecular octahedral cages with three types of chirality towards spontaneous resolution. Angew. Chem. Int. Ed., 2022, 61, e202203099\r
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Wang, H.; Guo, C.; Li, X.;* Multidimensional Mass Spectrometry Assisted Metallo-Supramolecular Chemistry, CCS Chem. 2021, 3, 3161–3184\r
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Wang, H.;# Wang, K.;# Xu, Y.;# Wang, W.;# Chen, S.; Hart, M.; Wojtas, L.; Zhou, L.-P.; Gan, L.; Yan, X.; Li, Y.; Lee, J.; Ke, X.-S.; Wang, X.-Q.; Zhang, C.-W.; Zhou, S.; Zhai, T.; Yang, H.-B.; Wang, M.; He, J.; Sun, Q.-F.; Xu, B.; Jiao, Y.; Stang, P. J.; Sessler, J. L.;* Li, X.;* Hierarchical Self-Assembly of Nanowires on the Surface by Metallo-Supramolecular Truncated Cuboctahedra, J. Am. Chem. Soc., 2021, 143, 5826-5835 (#: equal contribution to the work)\r
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Wang, H.; Zhou, L.-P.; Zheng, Y.; Wang, K.; Song, B.; Yan, X.; Wojtas, L.; Wang, X.-Q.; Jiang, X.; Wang, M.; Sun, Q.-F.; Xu, B.; Yang, H.-B.; Sue, A. C.-H.; Chan, Y.-T.; Sessler, J. L.; Jiao, Y.; Stang, P.J.; Li, X.* Double-Layered Supramolecular Prisms Self-Assembled by Geometrically Non-Equivalent Tetratopic Subunits. Angew. Chem. Int. Ed., 2021, 60, 1298-1305\r
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Wang, H.; Li, Y.; Li, N.; Filosa, A.; Li, X.;* Increasing the Size and Complexity of Discrete 2D Metallosupramolecules. Nature Rev. Mater. 2021, 6, 145-167\r
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Wang, Y.; Lu, S.; Wang, X.-Q.; Niu, Y.-F.; Wang, H.;* Wang, W.* Synthesis, Structure Elucidation and Functionalization of Sulfonamide [2]Catenanes, Org. Chem. Front., 2021, 8, 4994–5001\r
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Wang, L., Song, B., Khalif, S., Li, Y., Ming, L.-J., Bai, S., Xu, Y., Yu, H., Wang, M., Wang, H.,* Li, X.* Introducing Seven Transition Metal Ions into Terpyridine-Based Supramolecules: Self-Assembly and Dynamic Ligand Exchange Study, J. Am. Soc. Chem., 2020, 142, 1811-1821.\r
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Wang, H.;# Liu, C.-H.;# Wang, K.; Wang, M.; Yu, H.; Kandapal, S.; Brzozowski, R.; Xu, B.; Wang, M.; Eswara, P.; Nieh, M.-P.;* Cai, J.;* Li, X.* Assembling Pentatopic Terpyridine Ligand into Giant Supramolecular Hexagonal Prism with Three Types of Coordination Moieties: Synthesis, Self-Assembly, Characterization, and Antimicrobial Study. J. Am. Chem. Soc., 2019, 141, 16108-16116 (#: equal contribution to the work)\r
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Wang, H.; Li, Y.; Yu, H.; Song, B.; Lu, S.; Hao, X.-Q.; Zhang, Y.; Wang, M.; Hla, S.-W.; Li, X.* Combining Synthesis and Self-Assembly in One Pot to Construct Complex 2D Metallo-Supramolecules Using Terpyridine and Pyrylium Salts. J. Am. Chem. Soc., 2019, 141, 13187-13195\r
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Wang, H.;# Qian, X.;# Wang, K.; Su, M.; Haoyang, W.-W.; Jiang, X.; Brzozowski, R.; Wang, M.; Gao, X.; Li, Y.; Xu, B.; Eswara, P.; Hao, X.-Q.; Gong, W.;* Hou, J.-L.;* Cai, J.;* Li, X.* Supramolecular Kandinsky Circles with High Antibacterial Activity. Nature Commun., 2018, 9, 1815 (#: equal contribution to the work)\r
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Yin, G.-Q.;# Wang, H.;# Wang, X.-Q.; Song, B.; Chen, L.-J.; Wang, L.; Hao, X.-Q.; Yang, H.-B.;* Li, X.* Self-Assembly of Emissive Supramolecular Rosettes with Increasing Complexity Using Multitopic Terpyridine Ligands. Nature Commun., 2018, 9, 567 (#: equal contribution to the work)\r
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Zhang, Z.;# Wang, H.;# Wang, X.; Li, Y.; Song, B.; Bolarinwa, O.; Reese, R. A.; Zhang, T.; Wang, X.-Q.; Cai, J.; Xu, B.; Wang, M.;* Liu, C.;* Yang, H.-B.; Li, X.* Supersnowflakes: Stepwise Self-Assembly and Dynamic Exchange of Rhombus Star-Shaped Supramolecules. J. Am. Chem. Soc., 2017, 139, 8174–8185 (#: equal contribution to the work)\r
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Tang, J.-H., Ni R., He, Y.-Q., Vanderlinden, R. T., Li Y., Shi, B., Li Z.-Y., Wang, H.,* Li, X., Sun, Y.,* Zhong, Y.-W.,* Stang, P. J.*, Metal–Organic Pt(II) Hexagonal-Prism Macrocycles and Their Photophysical Properties, Inorg. Chem., 2019, 58, 13376-13381.\r
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Gu, Y.; Alt, E. A.; Wang, H.; Li, X.; Willard, A. P.; Johnson, J. A.* Photoswitching Topology in Polymer Networks with Metal–Organic Cages as Crosslinks. Nature, 2018, 560, 65–69\r
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Zhang, Z., Wang, H., Shi, J., Xu, Y., Wang, L., Shihadeh, S., Zhao, F.-J., Hao, X.-Q., Wang, P., Liu, C., Wang, M.*, Li, X.*, Stepwise Self-Assembly and Dynamic Exchange of Supramolecular Nanocages Based on Terpridine Building Blocks. Invited Contribution, Macromol. Rapid Commun., 2018, 39, 1800404.\r
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.Zhang, Z., Wang, H., Shi, J. Wang, P., Liu, C., Wang, M.*, Li, X.*, Stepwise Self–Assembly and Dynamic Exchange of Supramolecular Snowflakes Isr. J. Chem., 2018, 58, 1–12.\r
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Wang, H., Wang, Y., Ye, X., Hayama, H., Sugino, H., Nakano, H., Nakano, T.*, π-Stacked Poly(vinyl Ketone)s with Accumulated Push–Pull Triphenylamine Moieties in the Side Chain, Polym. Chem., 2017, 8, 708-714.\r
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Wang, H.; Pietropaolo, A., Wang, W., Chou, C., Hisaki, I., Tohnai, N., Miyata, M., Nakano, T.*, Right-handed 2/1 Helical Arrangement Benzene Molecules in Cholic Acid Crystal Established by Experimental and Theoretical Circular Dichroism Spectroscopy, RSC Adv., 2015, 5, 101110-101114.\r
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Wang, H.; Li, N.; Yan, Z.; Zhang, J.; Wan, X.*, Synthesis and Property of a Novel Cu(II)−Pyridineoxazoline Containing Polymeric Catalyst for Asymmetric Diels−Alder Reaction , RSC Adv., 2015, 5, 2882-2890.