个人简历

翟鑫，教授，博士生导师，第16届中国药学会施维雅青年药物化学奖获得者、霍英东基金会第十四届高校青年教师奖获得者，第十一届沈阳市优秀科技工作者，辽宁省“新世纪百千万人才工程百层次人选”，入选辽宁省高等学校优秀人才支持计划。主持省部级以上课题9项。在ScientificReport等期刊发表论文80余篇，SCI收录60篇。参编教材5部，授权专利12项。

研究领域

靶向抗肿瘤及抗感染药物的创新研发

近期论文

1.QiGuan,MingyangJiang,JunhuiWu,YanpengZhai,YueWu,KaiBao,WeigeZhang.DirectCyclebetweenCoproductandReactant:anApproachtoImproveAtomEconomyandApplicationsfortheSynthesisandProtectionofPrimaryAmines.GreenChemistry.2016,18(21),5794-5799(IF=8.506)
2.QileXu,YuetingWang,JingwenXu,MaolinSun,HaiqiuTian,DaiyingZuo,QiGuan,KaiBao,YingliangWu,WeigeZhang.SynthesisandBioevaluationof3,6-Diaryl-[1,2,4]triazolo[4,3-b]pyridazinesasAntitubulinAgents.ACSMedicinalChemistryLetters.2016,7(12),1202-1206(IF=3.355)
3.AilongShi,DefaWang,HeWang,YueWu,HaiqiuTian,QiGuan,KaiBao,WeigeZhang.SynthesisandBioevaluationof2-Phenyl-5-methyl-2H-1,2,3-triazole-4-carboxylicAcid/CarbohydrazideDerivativesasPotentXanthineOxidaseInhibitors.RSCAdvances.2016,6,114879-114888(IF=3.289)
4.ZhiweiWang,HuanQi,QirongShen,GuodongLu,MingyangLi,KaiBao,YingliangWu,WeigeZhang.4,5-Diaryl-3H-1,2-dithiole-3-thionesandTheirRelatedCompoundsasCombretastatinA-4/OltiprazHybrids:Synthesis,MolecularModelingandEvaluationasAntiproliferativeAgentsandInhibitorsofTubulin.EuropeanJournalofMedicinalChemistry.2016,122,520-529(IF=3.902)
5.ZhiyongWen,XiaonaLi,DaiyingZuo,BinyueLang,YangWu,MingyangJiang,HuizhuoMa,KaiBao,YingliangWu,WeigeZhang.Ultrasound-promotedTwo-stepSynthesisof3-Arylselenylindolesand3-ArylthioindolesasNovelCombretastatinA-4Analogues.ScientificReports.2016,6,23986,1-9(IF=5.228)
6.JingwenXu,DaiyingZuo,HuanQi,QirongShen,ZhaoshiBai,MengtingHan,ZengqiangLi,WeigeZhang,YingliangWu.2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl)Phenol(SQ0814061),ANovelMicrotubuleInhibitor,EvokesG2/MCellCycleArrestandApoptosisinHumanBreastCancerCells.Biomedicine&Pharmacotherapy.2016,78,308-321(IF=2.326)
7.JunSun,LeiChen,ChunjiangLiu,ZhanWang,DaiyingZuo,JiatongPan,HuanQi,KaiBao,YingliangWu,WeigeZhang.SynthesisandBiologicalEvaluationsof1,2-DiarylPyrrolesasAnaloguesofCombretastatinA-4.ChemicalBiology&DrugDesign.2015,86(6),1541-1547(IF=2.802)
8.QiGuan,DongjieFeng,ZhaoshiBai,YuanhangCui,DaiyingZuo,Min’anZhai,XueweiJiang,WenboZhou,KaiBao,YingliangWu,WeigeZhang.Microwave-assistedSynthesis,MolecularDockingandAntiproliferativeActivityof3/5-Aryl-5/3-(3,4,5-trimethoxybenzoyl)-1,2,4-oxadiazolDerivatives.MedChemComm.2015,6(8),1484-1493(IF=2.319)
9.QileXu,HuanQi,MaolinSun,DaiyingZuo,XueweiJiang,ZhiyongWen,ZhiweiWang,YingliangWu,WeigeZhang.SynthesisandBiologicalEvaluationof3-Alkyl-1,5-diaryl-1H-pyrazolesasRigidAnaloguesofCombretastatinA-4withPotentAntiproliferativeActivity.PLoSONE.2015,10(6),e0128710(IF=3.057)
10.KaiBao,FuqingLi,HanjingLiu,ZhiweiWang,QirongShen,JianWang,WeigeZhang.ActivatedCarbonforAerobicOxidation:BenignApproachtoward2-Benzoylbenzimidazolesand2-BenzoylbenzoxazolesSynthesis.ScientificReports.2015,5,10360,1-7(IF=5.228)