个人简历

秦铭泽，男，博士，副教授。2009年毕业于沈阳药科大学，获药学学士学位，2014年于同校获药物化学博士学位。2017年被聘为沈阳药科大学副教授。作为课题负责人主持了国家自然科学基金青年基金1项，辽宁省博士启动基金1项，辽宁省教育厅一般项目1项，沈阳药科大学科研专项基金1项。目前已在Eur.J.Med.Chem.,Bioorg.Med.Chem.等期刊发表论文10余篇。

研究领域

基于免疫调控及表观遗传的抗肿瘤新药设计

近期论文

1.YajingLiu,DiYang,ZexinHong,SuGuo,MoyiLiu,DaiyingZuo,DandanGe,MingzeQin,DeyuSun.Synthesisandbiologicalevaluationof4,6-diphenyl-2-(1H-pyrrol-1-yl)nicotinonitrileanaloguesofcrolibulinandcombretastatinA-4.Eur.J.Med.Chem.,2018,146:185-193.(IF:4.519)
2.MingzeQin,YeTian,XiaoqingSun,JuanjuanXia,PingGong,HaotianZhang,YanfangZhao.Novelmethylindolinone-6-carboxylatescontaininganindolemoietyasangiokinaseinhibitors.Eur.J.Med.Chem.,2017,139:492-502.(IF:4.519)
3.MingzeQin,ShuangYan,LeiWang,HaotianZhang,YeTian,YanfangZhao,PingGong.Novel6-MethoxycarbonylIndolinonesBearingaPyrroleMannichBaseMoietyasAngiokinaseInhibitors.Bioorg.Med.Chem.,2017,25,1778-1786.(IF:2.923)
4.YunleiHou,QiShen,ZefeiLi,ShaoweiChen,YanfangZhao,MingzeQin,PingGong.Palladium-catalyzedthree-componenttandemreactionforone-pothighlystereoselectivesynthesisof(Z)-α-hydroxymethylallylicsulfones.Adv.Synth.Catal.,DOI:10.1002/adsc.201701011.2018,360(4):631-636.(IF:5.646)
5.MingzeQin,ShuangYan,LeiWang,HaotianZhang,YanfangZhao,ShashaWu,DiWu,PingGong.Discoveryofnoveldiarylareaderivativesbearingatriazolemoietyaspotentialantitumoragents.Eur.J.Med.Chem.,2016,115:1-13.(IF:4.519)
6.MingzeQin,LeiWang,ShuangYan,JunjieMa,YeTian,YanfangZhao,andPingGong.Identificationofhydrazonemoiety-bearingaminopyrimidinesaspotentantitumoragentswithselectiveinhibitionofgefitinib-resistantH1975cancercells.ChineseChem.Lett.,2017,28,991-994.(IF:1.947)
7.YunleiHou,QiShen,LiangyuZhu,YufeiHan,YanfangZhao,MingzeQin,PingGong.Palladium-catalyzedthree-componenttandemreactionofsulfonylhydrazones,aryliodidesandallenes:highlystereoselectivesynthesisof(Z)-α-hydroxymethylallylicsulfones.RSCadvances,2017,7,50372-50377.
8.WenjingYe,QiYao,SimiaoYu,PingGong,MingzeQin.Synthesisandantitumoractivityoftriazole-containingsorafenibanalogs.Molecules,2017,22,1759.
9.YunleiHou#,MingzeQin#,XiuxiuYang,QiShen,YanfangZhao,YajingLiu,andPingGong.Palladium-catalyzedthree-componenttandemcyclizationofbuta-2,3-dien-1-ol,aryliodides,andimines:anefficientprotocolforthesynthesisofoxazolidinederivatives.RSCAdv.,2017,7,7401-7405.(IF:3.289).
10.MingzeQin,TingtingWang,BoxuanXu,ZonghuiMa,NanJiang,HongboXie,PingGong,YanfangZhao.Novelhydrazonemoiety-bearingaminopyrimidinesasselectiveinhibitorsofepidermalgrowthfactorreceptorT790Mmutant.Eur.J.Med.Chem.,2015,104:115-126.(IF:3.902)