个人简历

刘然，女，博士，副教授。2007年毕业于沈阳药科大学，获药物制剂学士学位，2011年于同校获药物分析学硕士学位，2014年于同校获药物分析学博士学位。作为课题负责人主持了国家自然科学基金青年基金项目1项，辽宁省科技厅项目1项、辽宁省教育厅项目1项，沈阳药科大学科研专项基金1项，沈阳药科大学中青年教师事业发展支持计划项目1项。目前已在AnalyticaChimicaActa,Talanta,Oncotarget等期刊发表论文10余篇。

研究领域

研究方向一：基于组学技术的中药现代化研究
研究方向二：药物动力学研究
研究方向三：药品质量标准研究

近期论文

1.LiuRan,LinXiaohui,LiZuojing,LiQing,BiKaishunQuantitativemetabolomicsforinvestigatingthevalueofpolyaminesintheearlydiagnosisandtherapyofcolorectalcancer,Oncotarget,AcceptedonNovember15,2017(IF5.168)
2.LiuRan,LiPei,BiWenchuan,MaRan,YinYidi,BiKaishun,LiQingPlasmaN-acetylputrescine,cadaverineand1,3-diaminopropane:potentialbiomarkersoflungcancerusedtoevaluatetheefficacyofanticancerdrugs,Oncotarget,2017;8:88575-88585(IF5.168)
3.LiuRan,XuHuarong,ZhangXiaowen,WangXiaotong,YuanZiyue,SuiZhenyu,WangDong,BiKaishun,LiQingMetabolomicsStrategyUsingHighResolutionMassSpectrometryRevealsNovelBiomarkersandPain-ReliefEffectofTraditionalChineseMedicinePrescriptionWu-Zhu-YuDecoctionActingonHeadacheModellingRats,Molecules,2017,22,2110,doi:3390/molecules22122110(IF2.861)
4.LiuRan,LiPei,XiaoJie,YinYidi,SunZheng,BiKaishun,LiQingAfast,sensitive,andhighthroughputmethodforthedeterminationofesomeprazoleindogplasmabyUHPLC-MS/MS:applicationtoformulationdevelopmentofthecompoundpreparationofesomeprazole,JournalofChromatographyB,2017,1068-1069:352-357(IF2.603)
5.DongShuya,HeJiao,HouHuiping,ShuaiYaping,WangQi,YangWenling,SunZheng,LiQing,BiKaishun,LiuRanQualityassessmentofHerbaLeonuribasedontheanalysisofmulti-componentsusingnormal-andreversed-phasechromatographicmethods,JournalofSeparationScience,2017;40:4482–4494(IF2.557)
6.LiuRan,MaRan,YuChunyu,BiWenchuan,YinYidi,XuHuarong,ShangHongwei,BiKaishun,LiQingQuantitationofelevenactivecompoundsofAidiinjectioninratplasmaanditsapplicationtocomparativepharmacokineticstudy,JournalofChromatographyB,2016;1026:105-113(IF2.603)
7.LiuRan,LiQing,MaRan,LinXiaohui,XuHuarong,BiKaishunDeterminationofpolyaminemetabolomeinplasmaandurinebyultrahighperformanceliquidchromatography-tandemmassspectrometrymethod:Applicationtoidentifypotentialmarkersforhumanhepaticcancer,AnalChimActa,2013;791:36-45(IF4.950)
8.LiuRan,BiKaishun,JiaYing,WangQian,YinRan,LiQingDeterminationofpolyaminesinhumanplasmabyhigh-performanceliquidchromatographycoupledwithQ-TOFmassspectrometry,JMassSpectrom,2012;47:1341-1346.(IF2.422)
9.LiuRan,JiaYing,ChengWeiming,LingJunhong,LiuLili.,BiKaishun,LiQingDeterminationofpolyaminesinhumanurinebyprecolumnderivatizationwithbenzoylchlorideandhigh-performanceliquidchromatographycoupledwithQ-time-of-flightmassspectrometry,Talanta,2011;83:751-756(IF4.162)
1.辽宁省药学会肿瘤精准医疗与大数据管理委员会理事；
2.中国仪器仪表学会药物质量分析与过程控制分会理事；