个人简历

邓意辉，男，博士，教授。1985年毕业于西安交通大学药学院（原西安医学院药学系），获药学士学位，1992年于沈阳药科大学获药剂学硕士学位，1999年于同校获药剂学博士学位。2005年被聘为沈阳药科大学教授。作为课题负责人主持或参与了国家自然科学基金项目6项，十一五重大项目1项、辽宁省科技厅科研项目1项，省科委研究项目2项、广东省课题1项及市委课题2项。目前已在国内外学术期刊发表论文186篇，其中SCI收载42篇。

研究领域

研究方向一：ABC现象及其机制探讨
研究方向二：新型“免疫伪装”载体的构建与机理研究；利用“MPS通路”实现肿瘤治疗的靶向研究
研究方向三：枯否细胞在清除PEG化纳米载体中的作用

近期论文

1.SongleiZhou,TingZhang,BoPeng,XiangLuo,XinrongLiu,LingHu,YangLiu,DonghuaDi,YanzhiSong,YihuiDeng*.Targeteddeliveryofepirubicintotumor-associatedmacrophagesbysialicacid-cholesterolconjugatemodifiedliposomeswithimprovedantitumoractivity.InternationalJournalofPharmaceutics.2017;523(1):203-16.(IF=4.320)
2.JingSu,YanzhiSong,MeiLu,XiangyunLin,YangLiu,SongleiZhou,YuqingSu,YihuiDeng*.Evaluationoftheantitumoreffectofdexamethasonepalmitateanddoxorubicinco-loadedliposomesmodifiedwithasialicacid–octadecylamineconjugate[J].EuropeanJournalofPharmaceuticalSciencesOfficialJournaloftheEuropeanFederationforPharmaceuticalSciences,2016,93:177.(IF=3.773)
3.TingZhang,SongleiZhou,LingHu,BoPeng,YangLiu,XiangLuo,YanzhiSong,XinrongLiu,YihuiDeng*.Polysialicacid-modifyingliposomesforefficientdeliveryofepirubicin,in-vitrocharacterizationandin-vivoevaluation[J].InternationalJournalofPharmaceutics.2016,515(1-2):449-459.(IF=3.994)
4.YanzhiSong,JieHan,RuiFeng,MengjingWang,QingjingTian,TingZhang,XinrongLiu,XiaoboCheng,YihuiDeng*.The12-3-12cationicGeminisurfactantasanovelgastrointestinalbioadhesivematerialforimprovingtheoralbioavailabilityofcoenzymeQ10nakednanocrystals[J].DrugDevelopment&IndustrialPharmacy.2016,42(12):1-25.(IF=2.429)
5.XiangLuo,YanyanZhou,LongBai,FuguoLiu,YihuiDeng*,DavidJulianMcClements*.Fabricationofβ-carotenenanoemulsion-baseddeliverysystemsusingdual-channelmicrofluidization:Physicalandchemicalstability[J].JournalofColloid&InterfaceScience.2016,490:328.(IF=3.782)
6.ChunlingWang,XiaoboCheng,YuqingSu,YingPei,YanzhiSong,JiaoJiao,ZhenjunHuang,YanfeiMa,YinmingDong,YingYao,JingjingFan,HanTa,XinrongLiu,HuiXu,YihuiDeng*.Acceleratedbloodclearancephenomenonuponcross-administrationofPEGylatednanocarriersinbeagledogs[J].InternationalJournalofNanomedicine.2015,10:3533-3545.(IF=4.320)
7.XulingWang,YanzhiSong,YuqingSu,QingjingTian,BoqunLi,JingjingQuan,YihuiDeng*.ArePEGylatedliposomesbetterthanconventionalliposomes?Aspecialcaseforvincristine[J].DrugDelivery.2016,23(4):1092-1100.(IF=4.843)
8.HuanXu,FeifeiYe,MeinaHu,PengpengYin,WeiZhang,YanLi,XiuYu,YihuiDeng*.InfluenceofphospholipidtypesandanimalmodelsontheacceleratedbloodclearancephenomenonofPEGylatedliposomesuponrepeatedinjection[J].DrugDelivery.2015,22(5):598-607.(IF=4.843)
9.YanzhiSong,ZhenjunHuang,YangSong,QingjingTian,XinrongLiu,ZhennanShe,JiaoJiao,ElizaLu,YihuiDeng*.TheapplicationofEDTAindrugdeliverysystems:doxorubicinliposomesloadedviaNH4EDTAgradient[J].InternationalJournalofNanomedicine.2014,9:3611-3621.(IF=4.320)
10.ZhennanShe,TingZhang,XulingWang,XuanLi,YanzhiSong,XiaoboCheng,ZhenjunHuang,YihuiDeng*.Theanticancerefficacyofpixantrone-loadedliposomesdecoratedwithsialicacid-octadecylamineconjugate[J].Biomaterials.2014,35(19):5216-5225.(IF=8.383)