个人简历

丁怀伟，男，博士，特聘副教授。2006年毕业于沈阳药科大学，获中药学学士学位，2009年于同校获天然药物化学硕士学位，2012年于同校获药物化学博士学位，博士论文于清华大学深圳研究生院联合培养完成，2018年评为沈阳药科大学特聘副教授。作为课题参与人参与了国家自然科学基金面上项目1项；主持辽宁省教育厅项目1项，沈阳药科大学科研基金项目2项，完成横向课题5项。目前已在EuropeanJournalofMedicinalChemistry、Bioorganic&MedicinalChemistry、MedicinalChemistryCommunications、Chinesejournaloforganicchemistry等期刊发表SCI论文9篇，申请相关专利9项，其中授权3项。

研究领域

研究方向一：基于靶点的抗肿瘤化合物的设计、合成与生物活性研究
研究方向二：基于活性的天然产物的结构优化
研究方向三：抗糖尿病化合物的设计、合成与生物活性研究

近期论文

1.Huai-WeiDing,Cheng-LongDeng,Dan-DanLi,Dan-DanLiu,Shao-MengChai,WeiWang,YanZhang,KaiChen,XinLi,JianWang,Shao-JiangSong,Hong-RuiSong.Design,synthesisandbiologicalevaluationofnovel4-aminoquinazolinesasdualtargetinhibitorsofEGFR-PI3Kα.EuropeanJournalofMedicinalChemistry,2018,146:460-470.(IF=4.519)
2.YanXiao,JuanLi,Ya-junLiu,ShuoWang,HuiZhang*,andHuai-weiDing*.Copper(II)CatalyzedC-HAlkoxylationof2-PhenylPyridineswithAliphaticDiols.EuropeanJournalofOrganicChemistry.https://doi.org/10.1002/ejoc.201800104.(IF=2.834)
3.Yan-HuaFan,Huai-weiDing*,Dan-DanLiu,Hong-RuiSong,Yong-NanXu,JianWang.Novel4-aminoquinazolinederivativesinducegrowthinhibition,cellcyclearrestandapoptosisviaPI3Kαinhibition.Bioorganic&MedicinalChemistry.2018,26(8):1675-1685.(IF=2.93)
4.Huai-WeiDing,Bing-keSong,Cheng-longDeng,WeiLi,LiNiu,Meng-xuanBai,Hong-ruiSong*andLi-juanZhang*.SynthesisandSmoActivityofSomeNovelBenzamideDerivatives.[J].Molecules,2018,23(1),85.(IF=2.861)
5.YanHuaFan,WeiLi,DanDanLiu,MengXuanBai,HongRuiSong,YongNanXu,SangKookLee,ZhiPengZhou,JianWang,HuaiweiDing*.Design,synthesis,andbiologicalevaluationofnovel3-substitutedimidazo[1,2-a]pyridineandquinazolin-4(3H)-onederivativesasPI3Kαinhibitors.EuropeanJournalofMedicinalChemistry,2017,139:95-106.(IF=4.519)
6.Huai-WeiDing,JuanLi,Qing-HuiGuo,YanXiao*.ResearchProgressonTransition-Metal-CatalyzedC-HActivation/C-OCouplingReactionofArenes.Chinesejournaloforganicchemistry.2017,37:3112-3129.(IF=1.010)
7.Xiao-fengChen,Chi-yuSun,Jing-zhouZhang,HuaiweiDing*HongruiSong*.Design,synthesisandevaluationofnoveltetrahydrothieno[3,2-c]pyridinederivativesaspotentsmoothenedantagonists,Med.chem.commun,2016,7(5):960-965.(IF=2.608)
8.ChiyuSun,YangshengLi,AilongShi,JingzhouZhang,YafeiLi,MingmingZhao,LijuanZhang,HuachuanZheng,HuaiweiDing*,HongruiSong*.SynthesisandevaluationofnovelN-3-benzimidazole-phenylbisamidederivativesforantiproliferativeandhedgehogpathwayinhibitoryactivity.MedicinalChemistryCommunications,2015,6(6),1137-1142.(IF=2.319)
9.Chi-yuSun,Yang-shengLi,Ai-longShi,Ya-feiLi,Rui-fangCao,Huai-weiDing*,Qing-qingYin,Li-juanZhang,Hua-chuanZheng,Hon-gruiSong*.Synthesisandantiproliferativeactivityofnovel4-substituted-phenoxyl-benzamidederivatives.ChineseChemicalLetters.2015,26(10):1307-1310.(IF=1.947)