个人简历

2002/07 – 至今，山西大学，化学化工学院\r
1999/09 – 2002/07，南开大学，博士\r
1995/09 – 1998/07，山西大学，硕士\r
1991/09 – 1995/07，山西大学，学士

研究领域

"""""荧光染料、探针的开发及生物医学应用"

近期论文

Xin Lv, Chunmei Gao, Taihe Han, Hu Shi and Wei Guo*; Improving the quantum yields of fluorophores by inhibiting twisted intramolecular charge transfer using electron-withdrawing group-functionalized piperidine auxochromes; Chem. Commun., 2020, 56, 715-718.\r
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Hu Shi,* Hao Li, Wenlong Gong, Ruiting Gong, Aniu Qian, Jin Yong Lee, and Wei Guo*; Structural and Binding Properties on Ab Mature Fibrils Due to the Histidine Tautomeric Effect, ACS Chem. Neurosci., 2019, 10, 4612−4618.\r
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Minghao Ren, Linfang Wang, Xin Lv, Yuanqiang Sun, Hu Chen, Keyuan Zhang, Qi Wu, Yurong Bai and Wei Guo*; A rhodol-hemicyanine based ratiometric fluorescent probe for real-time monitoring of glutathione dynamics in living cells; Analyst, 2019, 144, 7457–7462.\r
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Jing Liu, Mengxing Liu, Hongxing Zhang, Xuehong Wei, Juanjuan Wang, Ming Xian* and Wei Guo*; Exploring cysteine regulation in cancer cell survival with a highly specific “Lock and Key” fluorescent probe for cysteine; Chem. Sci., 2019, 10, 10065–10071.\r
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Minghao Ren, Linfang Wang, Xin Lv,* Jing Liu, Hu Chen, Juanjuan Wang and Wei Guo*; Development of a benzothiazole-functionalized red-emission pyronin dye and its dihydro derivative for imaging lysosomal viscosity and tracking endogenous peroxynitrite; J. Mater. Chem. B, 2019, 7, 6181-6186.\r
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Yingying Huo, Junfeng Miao, Junru Fang, Hu Shi, Juanjuan Wang, and Wei Guo*; Aromatic secondary amine-functionalized fluorescent NO probes: improved detection sensitivity for NO and potential applications in cancer immunotherapy studies; Chem. Sci., 2019, 10, 145–152.\r
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Junfeng Miao, Yingying Huo, Hu Shi, Junru Fang, Juanjuan Wang, and Wei Guo*; A Si-rhodamine-based near-infrared fluorescent probe for visualizing endogenous peroxynitrite in living cells, tissues, and animals; J. Mater. Chem. B, 2018, 6, 4466-4473.\r
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Hongxing Zhang, Jing Liu, Bo Hu, Linfang Wang, Zhen Yang, Xu Han, Juanjuan Wang, Wei Bai, and Wei Guo*; Dual-Channel Fluorescence Diagnosis of Cancer Cells/Tissues Assisted by OATP Transporters and Cysteine/Glutathione; Chem. Sci., 2018, 9, 3209–3214.\r
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Hongxing Zhang, Jing Liu, Linfang Wang, Minjia Sun, Xiaohan Yan, Juanjuan Wang, Jian-Ping Guo, and Wei Guo*; Amino-Si-Rhodamines: a New Class of Two-Photon Fluorescent Dyes with Intrinsic Targeting Ability for Lysosomes; Biomaterials, 2018, 158, 10-22.\r
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Xin Lv,* Xia Yuan, Yue Wang and Wei Guo*; A naphthalimide based fast and selective fluorescent probe for hypochlorous acid/hypochlorite and its application for bioimaging; New J. Chem., 2018, 42, 15105-15110.\r
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Yingying Huo, Junfeng Miao, Lingjun Han, Yaping Li, Zhe Li, Yawei Shi, and Wei Guo*; Selective and Sensitive Visualization of Endogenous Nitric Oxide in Living Cells and Animals by a Si-Rhodamine Deoxylactam-Based Near-Infrared Fluorescent Probe; Chem. Sci., 2017, 8, 6857-6864.\r
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Hongxing Zhang, Jing Liu, Chenlu Liu, Pengcheng Yu, Minjia Sun, Xiaohan Yan, Jian-Ping Guo, Wei Guo*; Imaging lysosomal highly reactive oxygen species and lighting up cancer cells and tumors enabled by a Si-rhodamine-based near-infrared fluorescent probe; Biomaterials, 2017, 133, 60-69.\r
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Yun Zhao*, Yuanyuan Xue, Haoyang Li, Ruitao Zhu Yuehong Ren, Qinghua Shi, Song Wang, Wei Guo*; An excited state intramolecular proton transfer dye based fluorescence turn-on probe for fast detection of thiols and its applications in bioimaging; Spectrochim. Acta, Part A, 2017, 175, 215-221.\r
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Yue Wang, Xin Lv*, Wei Guo**; A reaction-based and highly selective fluorescent probe for hydrogen sulfide; Dyes and Pigments, 2017, 139, 482-486.\r
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Yingying Huo, Junfeng Miao, Yaping Li, Yawei Shi, Heping Shi and Wei Guo*; Aromatic primary monoamine-based fast-response and highly specific fluorescent probes for imaging the biological signaling molecule nitric oxide in living cells and organisms; J. Mater. Chem. B, 2017, 5, 2483-2490.\r
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Junfeng Miao, Yingying Huo, Qian Liu, Zhe Li, Heping Shi, Yawei Shi, and Wei Guo*; A new class of fast-response and highly selective fluorescent probes for visualizing peroxynitrite in live cells, subcellular organelles, and kidney tissue of diabetic rats; Biomaterials, 2016, 107, 33-43.\r
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Junfeng Miao, Yingying Huo, Xin Lv, Zhe Li, Hualiang Cao, Heping Shi, Yawei Shi, and Wei Guo*; Fast-response and highly selective fluorescent probes for biological signaling molecule NO based on N-nitrosation of electron-rich aromatic secondary amines; Biomaterials, 2016, 78, 11.\r
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Jing Liu, Yuan-Qiang Sun, Hongxing Zhang, Heping Shi, Yawei Shi, and Wei Guo*; Sulfone-Rhodamines: A New Class of Near-Infrared Fluorescent Dyes for Bioimaging; ACS Applied Materials & Interfaces. 2016, 8, 22953.\r
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Jian Zhang, Yaping Li, Jingjing Zhao, and Wei Guo*; An arylboronate-based fluorescent probe for selective and sensitive detection of peroxynitrite and its applications for fluorescence imaging in living cells; Sensors and Actuators B, 2016, 237, 67–74.\r
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Yue Wang, Yawei Liu, Junfeng Miao, Minghao Ren, Wei Guo, Xin Lv*; A novel Bodipy-based fluorescent probe for Au3+ ions with high selectivity and its application to bioimaging; Sensors and Actuators B, 2016, 226, 364–369.