黄诚
近期热点
资料介绍
个人简历
黄诚研究员上海中医药大学,中药学院,研究员。目前从事抗肿瘤和治疗内分泌代谢性疾病的药物筛选和新靶点的鉴定,旨在从中药中发现具有减肥、降血糖、降血脂和抗肿瘤作用的新化合物或复方中药。共发表论文60余篇。受教育经历1994/9-1997/7,上海中医药大学,博士1987/9-1990/7,上海中医药大学,硕士1979/10-1982/10,扬州大学医学院研究工作经历2009/7-至今,上海中医药大学中药学院,研究员2006/11-2007/5,美国肯塔基大学医学院,访问科学家2005/7-2009/7,中国科学院营养科学研究所,副研究员2002/11-2005/6,美国贝勒医学院分子与人类遗传系,ResearchAssociate2001/6-2002/11,美国贝勒医学院儿科系,博士后1999/9-2001/6,中国科学院上海生理研究所,副研究员1997/9-1999/9,中国科学院上海生理研究所,博士后1990/7-1997/9,上海市针灸经络研究所,助理研究员/副研究员所获荣誉、奖项1.季光,王峥涛,黄诚,刘建文,王淼,吴涛,杨丽丽,张莉,宋海燕,柳涛,孙姗姗,范圣洁,魏华凤,郑培永,邢练军,安红梅,王磊,励冬斐,刘洋,潘洁露,舒祥兵,徐汉辰。基于病证结合中医药治疗非酒精性脂肪肝的转化医学研究,教育部,科技进步奖,二等奖,2014年1月。2.季光,张莉,魏华凤,宋海燕,郑培永,刘建文,黄诚,杨丽丽,王淼,柳涛,杨莉,安红梅,吴涛,邢练军,王磊。基于病证结合中医药治疗非酒精性脂肪肝的转化医学实践,上海市,科学技术奖,一等奖,2013年12月12日。近期论文
1.LiuG,ZhangY,LiuC,XuD,ZhangR,ChengY,PanY,HuangC,ChenY.Luteolinalleviatesalcoholicliverdiseaseinducedbychronicandbingeethanolfeedinginmice.JNutr.144(7):doi:10.3945/jn.114.193128.(2014).2.HuangC*.NaturalmodulatorsofliverXreceptors.JIntegrMed.7(2):76-85,(2014).3.FanS,ZhangY,SunQ,ZhengB,WuX,YangB,LiY,HuangC*.Extractofokralowersbloodglucoseandserumlipidsinhigh-fatdietinducedobeseC57BL/6mice.JNutrBiochem.25:(2014).4.TanS,LiM,DingX,FanS,GuoL,GuM,ZhangY,FengL,JiangD,LiY,XiW,HuangC*,ZhouZ*.EffectsofFortunellamargaritafruitextractonmetabolicdisorderinhigh-fatdiet-inducedobeseC57BL/6mice.PLoSOne.9(4):e93510,(2014).5.LiJ,ZhangL,HuangC,GuoF,LiY.FivenewcyotoxicsteroidalglycosidesfromthefruitsofSolanumtorvum.Fitoterapia.93:209-215,(2014).6.LuY,XiW,DingX,FanS,ZhangY,JiangD,LiY,HuangC*,ZhouZ*.Citrangefruitextractsalleviateobesity-associatedmetabolicdisorderinhigh-fatdietinducedC57BL/6mouse.IntJMolSci.14:23736-23750,(2013).7.FengL,LiuX,ZhuW,GuoF,WuY,WangR,ChenK,HuangC*,LiY*.Inhibitionofhumanneutrophilelastasebypentacyclictriterpenes.PLoSOne.8(12):e82794,(2013).8.GuM,ZhangY,FanS,DingX,JiG*,HuangC*.ExtractsofRhizomaPolygonatiOdoratipreventhigh-fatdiet-inducedmetabolicdisordersinC57BL/6mice.PLoSOne.8(11):e81724,(2013).9.DingX,GuoL,ZhangY,FanS,GuM,LuY,JiangD,LiY*,HuangC*,ZhouZ*.Extractsofpomelopeelspreventhigh-fatdiet-inducedmetabolicdisordersinC57BL/6micethroughactivatingthePPARαandGLUT4pathway.PLoSOne.8(10):e77915,(2013).10.FanS,GuoL,ZhangY,SunQ,YangB,HuangC*.Okrapolysaccharideimprovesmetabolicdisordersinhigh-fatdiet-inducedobeseC57BL/6mice.MolNutrFoodRes.57:2075-2078,(2013).11.JingL,ZhangY,FanS,GuM,GuanY,LuX,HuangC*,ZhouZ*.Preventiveandamelioratingeffectsofcitrusd-limoneneondyslipidemiaandhyperglycemiainmicewithhigh-fatdiet-inducedobesity.EurJPharmacol.715:46-55,(2013).12.GuoF,FengL,HuangC,DingH,ZhangX,WangZ,LiY.PrenylflavonederivativesfromBroussonetiapapyrifera,inhibitthegrowthofbreastcancercellsinvitroandinvivo.PhytoLett.6:331-336,(2013).13.HuN,YuanL,LiH-J,HuangC,MaoQ-M,ZhangY-Y,LinM,SunY-Q,ZhongX-Y,TangP,LuX.Anti-diabeticactivitiesofJiaotaiwanindb/dbmicebyaugmentationofAMPKproteinactivityandup-regulationofGLUT4expression.Evid-BasedComplAltMed.180721,(2013).14.顾明,黄诚*.减肥药研发:窘境背后的希望.中国新药杂志.22(5):535-541,(2013).15.FengQ,GouXJ,MengSX,HuangC,ZhangYQ,TangYJ,WangWJ,XuL,PengJH,HuYY.QushiHuayuDecoctionInhibitsHepaticLipidAccumulationbyActivatingAMP-ActivatedProteinKinaseInVivoandInVitro.Evid-BasedComplAltMed.184358,(2013).16.GuM,FanS,LiuG,GuoL,DingX,LuY,ZhangY,JiG,HuangC*.Extractofwaxgourdpeelpreventshigh-fatdiet-inducedhyperlipidemiainC57BL/6miceviatheinhibitionofthePPARγpathway.Evid-BasedComplAltMed.342561,(2013).17.FanS,ZhangY,HuN,SunQ,DingX,LiG,ZhengB,GuM,HuangF,SunY-Q,ZhouZ,LuX,HuangC*,JiG*.Extractofkudingteapreventshigh-fatdiet-inducedmetabolicdisordersinC57BL/6micevialiverXreceptor(LXR)βantagonism.PLoSOne.7(12):e51007,(2012).18.DingX,FanS,LuY,ZhangY,GuM,ZhangL,LiuG,GuoL,LiY,LuX,ZhouZ*,HuangC*.Citrusichangensispeelextractexhibitsanti-obesityeffectsbytheinhibitionofPPARγandLXRsignalinginhigh-fatdiet-inducedC57BL/6mouse.Evid-BasedComplAltMed.678592,(2012).19.ZhangL,FanS,LiuH,HuangC*.TargetingSMARCAL1asanovelstrategyforcancertherapy.BiochemBiophysResCommun.427:232-235,(2012).20.ZhangY,FanS,HuN,GuM,ChuC,LiY,LuX,HuangC*.Rheinreducesfatweightindb/dbmouseandpreventsdiet-inducedobesityinC57BL/6mousethroughtheinhibitionofPPARγsignaling.PPARRes.374936,(2012).21.LiY,HuangW,HuangS,DuJ*,HuangC*.Screeningofanti-canceragentusingzebrafish:ComparisonwiththeMTTassay.BiochemBiophysResCommun.422:85-90,(2012).22.ZhangY,HuangC*.Targetingadipocyteapoptosis:Anovelstrategyforobesitytherapy.BiochemBiophysResCommun.417:1-4,(2012)23.WangP,GuoF,TanJ,HuangC,WangG,LiY.AnovelC29sterolfromClerodendrumcyrtophyllum.ChemNatComp.48:594-596,(2012).24.FengL,ZhuW,HuangC,LiY.DirectinteractionofONO-5046withhumanneutrophilelastasethrough1HNMRandmoleculardocking.IntJBiolMacromo.51:196-200,(2012).25.GaoN,ChengS,BudhrajaA,GaoZ,ChenJ,LiuE-H,HuangC,ChenD,YangZ,LiuQ,LiP,ShiX,ZhangZ.Ursolicacidinducesapoptosisinhumanleukaemiacellsandexhibitsanti-leukaemicactivityinnudemicethroughthePKBpathway.BrJPharmacol.165:1813-1826,(2012).26.WangY,FengL,ZhangB,WangX,HuangC,LiY,DuW.PalladiumcomplexesaffecttheaggregationofhumanprionproteinPrP106-126.InorgChem.50:4340-4348,(2011).27.GaoN,BudhrajaA,ChengS,LiuE-H,HuangC,ChenJ,YangZ,ChenD,ZhangZ,ShiX.InterruptionoftheMEK/ERKsignalingcascadepromotesdihydroartemisinin-inducedapoptosisinvitroandinvivo.Apoptosis.16:511-523,(2011).28.李乙根,黄文瑾,黄诚*.斑马鱼在新药发现中的应用。生命科学,23:273-278,(2011).29.ChenC,ZhangY,HuangC*.BerberineinhibitsPTP1Bactivityandmimicsinsulinaction.BiochemBiophysResCommun.397:543-547,(2010).30.HuangC*,GuS,YuP,YuF,FengC,GaoN,DuJ.Deficiencyofsmarcal1causescellcyclearrestanddevelopmentalabnormalitiesinzebrafish.DevBiol.339:89-100,(2010). 相关热点
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