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冯陈国
2023-05-12 22:33
  • 冯陈国
  • 冯陈国 - 研究员-上海中医药大学-创新中药研究院-个人资料

近期热点

资料介绍

个人简历


2017.05-目前 研究员,上海市中医药大学创新中药研究院手性药物研究中心\r
2014.05-2017.05\t副研究员,中国科学院上海有机化学研究所\r
2011.08-2013.08\t访问学者,美国Scripps研究所,导师:Jin-Quan Yu(余金权)教授\r
2006.09-2009.06\t助理研究员,中国科学院上海有机化学研究所\r
2004.09-2006.09\t研究实习员,中国科学院上海有机化学研究所\r
2001.09-2004.09\t理学硕士,厦门大学化学系有机合成专业,导师:黄培强教授\r
1997.09-2001.06\t理学学士,浙江大学化学系,导师:林贤福教授

研究领域


"""""中药活性成分有机合成和结构改造\r
方法学导向的天然产物和药物分子合成\r
药物分子合成工艺优化\r
过渡金属催化的高效和高选择性反应研究"

近期论文


Zhang, Ge; Song, Yi-Kang; Zhang, Fang; Xue, Ze-Jian; Li, Meng-Yao; Zhang, Gui-Shan; Zhu, Bin-Bin; Wei, Jing; Li, Chunsen; Feng, Chen-Guo; Lin, Guo-Qiang Palladium-Catalyzed Allene Synthesis Enabled by Beta-Hydrogen Elimination from Sp2-Carbon. Nature communications 2021, 12, 728-728.\r
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Zhang, Ge; Li, Meng-Yao; Ye, Wen-Bo; He, Zhi-Tao; Feng, Chen-Guo; Lin, Guo-Qiang Borylation of Unactivated C(Sp(3))-H Bonds with Bromide as a Traceless Directing Group. Org. Lett. 2021, 23, 2948-2953.\r
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Xue, Ze-Jian; Li, Meng-Yao; Zhu, Bin-Bin; He, Zhi-Tao; Feng, Chen-Guo; Lin, Guo-Qiang A 1,4-Palladium Migration/Heck Sequence with Unactivated Alkenes: Stereoselective Synthesis of Trisubstituted 1,3-Dienes. Adv. Synth. Catal. 2021, 363, 2089-2092.\r
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Xu, Si-Yu; Zhang, Rui; Zhang, Shu-Sheng; Feng, Chen-Guo Enantioselective Synthesis of 3-Aryl-Phthalides through a Nickel-Catalyzed Stereoconvergent Cross-Coupling Reaction. Organic & Biomolecular Chemistry 2021, 19, 4492-4496.\r
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Tian, Tian; Zhou, Bo-wen; Wu, Li-hong; Zhang, Fang; Chou, Gui-xin; Feng, Chen-guo; Lin, Guo-qiang Non-Targeted Screening of Pyranosides in Rhodiola Crenulata Using an All Ion Fragmentation-Exact Neutral Loss Strategy Combined with Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry. Phytochem. Anal 2021.\r
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Song, Yi-Kang; Xu, Si-Yu; Zhang, Shu-Sheng; Fu, Jian-Guo; Lin, Guo-Qiang; Feng, Chen-Guo Palladium-Catalyzed Tandem Gamma-Arylation/Aromatization of Cyclohex-2-En-1-One Derivatives: A Route to 3,4-Dihydroanthracen-1(2h)-Ones. Adv. Synth. Catal. 2021, 363, 3001-3005.\r
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Song, Yi-Kang; Liu, Li; Wang, Jun-Jie; Qian, Fei; Yang, Mao-Qi; Zhang, Liu-Qiang; Fu, Jian-Guo; Li, Yi-Ming; Feng, Chen-Guo An Asymmetric Synthesis of (+)-Scrodentoid a from Dehydroabietic Acid. Tetrahedron 2021, 85, 132031.\r
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Zhang, Ge; Fu, Jian-Guo; Zhao, Qian; Zhang, Gui-Shan; Li, Meng-Yao; Feng, Chen-Guo; Lin, Guo-Qiang Silver-Promoted Synthesis of Vinyl Sulfones from Vinyl Bromides and Sulfonyl Hydrazides in Water. Chem. Commun. 2020, 56, 4688-4691.\r
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Xue, Ze-Jian; Li, Meng-Yao; Zhu, Bin-Bin; He, Zhi-Tao; Feng, Chen-Guo; Lin, Guo-Qiang Stereoselective Synthesis of Conjugated Trienes Via 1,4-Palladium Migration/Heck Sequence. Chem. Commun. 2020, 56, 14420-14422.\r
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Li, Meng-Yao; Han, Pengbo; Hu, Tian-Jiao; Wei, Dong; Zhang, Ge; Qin, Anjun; Feng, Chen-Guo; Tang, Ben Zhong; Lin, Guo-Qiang Suzuki-Miyaura Coupling Enabled by Aryl to Vinyl 1,4-Palladium Migration. Iscience 2020, 23, 100966.\r
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Zhou, Jing; Zhang, Hong; Chen, Xue-Lian; Qu, Ya-Li; Zhu, Qianqian; Feng, Chen-Guo; Chen, Ya-Jing Regio- and Diastereoselective Access to 4-Imidazolidinones Via an Aza-Mannich Initiated Cyclization of Sulfamate-Derived Cyclic Imines with Alpha-Halo Hydroxamates. J. Org. Chem. 2019, 84, 9179-9187.\r
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Zhang, Shu-Sheng; Hu, Tian-Jiao; Li, Meng-Yao; Song, Yi-Kang; Yang, Xiao-Di; Feng, Chen-Guo; Lin, Guo-Qiang Asymmetric Alkenylation of Enones and Imines Enabled by a Highly Efficient Aryl to Vinyl 1,4-Rhodium Migration. Angew. Chem. Int. Ed. 2019, 58, 3387-3391.\r
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Zhang, Ge; Bai, Rui-Xue; Li, Chu-Han; Feng, Chen-Guo; Lin, Guo-Qiang Halogenation of 1,1-Diarylethylenes by N-Halosuccinimides. Tetrahedron 2019, 75, 1658-1662.\r
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Wei, Dong; Li, Meng-Yao; Zhu, Bin-Bin; Yang, Xiao-Di; Zhang, Fang; Feng, Chen-Guo; Lin, Guo-Qiang Sequential Cross-Coupling/Annulation of Ortho-Vinyl Bromobenzenes with Aromatic Bromides for the Synthesis of Polycyclic Aromatic Compounds. Angew. Chem. Int. Ed. 2019, 58, 16543-16547.\r
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Lv, Shao-Dong; Tian, Tian; Zhang, Liu-Qiang; Xu, Si Yu; Zhao, Dong-Hai; Wang, Jun-Jie; Fu, Jian-Guo; Li, Yi-Ming; Feng, Chen-Guo Total Synthesis of (+/-)-Scrodentoid A. Tetrahedron 2019, 75, 130774-130775.\r
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Wei, Dong; Hu, Tian-Jiao; Feng, Chen-Guo; Lin, Guo-Qiang Synthesis of Substituted Naphthalenes by 1,4-Palladium Migration Involved Annulation with Internal Alkynes. Chin. J. Chem . 2018, 36, 743-748.\r
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Meng, Jiao-Long; Jiao, Tang-Qian; Chen, Ya-Heng; Fu, Rui; Zhang, Shu-Sheng; Zhao, Qian; Feng, Chen-Guo; Lin, Guo-Qiang Synthesis of Chiral Isoindolinones Via Asymmetric Propargylation/Lactamization Cascade. Tetrahedron Lett. 2018, 59, 1564-1567.\r
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Hu, Tian-Jiao; Li, Meng-Yao; Zhao, Qian; Feng, Chen-Guo; Lin, Guo-Qiang Highly Stereoselective Synthesis of 1,3-Dienes through an Aryl to Vinyl 1,4-Palladium Migration/Heck Sequence. Angew. Chem. Int. Ed. 2018, 57, 5871-5875.\r
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Ge, Yao; Han, Zhaobin; Wang, Zheng; Feng, Chen-Guo; Zhao, Qian; Lin, Guo-Qiang; Ding, Kuiling Ir-Spinphox Catalyzed Enantioselective Hydrogenation of 3-Ylidenephthalides. Angew. Chem. Int. Ed. 2018, 57, 13140-13144.

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