研究领域

"""""噬菌体展示结合高通量筛选排序技术研究蛋白质结构与功能之间的关系。"

近期论文

1.A Strategy for Modulation of Enzymes in the Ubiquitin System. Ernst, A., Avvakumov, G., Tong, J., Fan, Y., Zhao, Y., Alberts, P., Persaud, A., Walker, J.R., Neculai, A.M., Neculai, D., Vorobyov, A., Garg, P., Beatty, L., Chan, P.K., Juang, Y.C., Landry, M.C., Yeh, C., Zeqiraj, E., Karamboulas, K., Allali-Hassani, A., Vedadi, M., Tyers, M., Moffat, J., Sicheri, F., Pelletier, L., Durocher, D., Raught, B., Rotin, D., Yang, J., Moran, M.F., Dhe-Paganon, S., Sidhu, S.S. Science. 2013; 339, 590-5.
2.Inhibition of Wnt/b-catenin signaling by peptides that target dishevelled PDZ domains. Zhang, Y., Appleton, B.A., Wiesmann, C., Lau, T., Costa, M., Hannoush, R. N., Sidhu, S.S. Nat. Chem. Biol. 2009; 5, 217-9.
3.A specificity map for the PDZ domain family. Tonikian, R., Zhang, Y., Sazinsky, S.L., Currell, B., Yeh, J.-H., Reva, B., Held, H.A., Appleton, B.A., Evangelista, M., Wu, Y., Xin, X., Chan, A.C., Seshagiri, S., Sander, C., Lasky, L.A., Boone, C., Bader, G.D. Sidhu, S.S. PLoS Biol. 2008; 6, e239.
4.Synthetic therapeutic antibodies. Sidhu, S.S., Fellouse, F.A. Nat. Chem. Biol. 2006, 12, 682-8.