个人简历

Education\r
2012, Ph. D in Biochemistry, University of Maryland, College Park, United States\r
2006, B. S. in Biological Sciences, Nankai University, P. R. China\r
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Professional\r
2014-present, Research Associate Professor, Shanghai Advanced Immunochemical Studies (SIAIS), ShanghaiTech University\r
2012-2014, postdoctoral fellow, The Scripps Research Institute, La Jolla

研究领域

"""""Antibody-drug conjugates: plant-derived toxins

近期论文

Liu, J., Sun, Y., Zhang, X., Liang, X., Wu, Y., Wang, Y. and Jiang, X. (2014) Spirooxindoles, a potential novel class of anti-inflammatory agents. Inflamm. Cell Signal., 1, e372.\r
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Gaj, T., Liu, J., Anderson, K. E., Sirk, S. J., Barbas, C. F. III (2014) Protein delivery using Cys2-His2 zinc-finger domains. ACS Chem. Biol. 9, 1662-1667.\r
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Sun, Y., Liu, J., Sun, T., Zhang, X., Yao, J., Kai, M., Jiang, X. and Wang, R. (2014) Anti-cancer small molecule JP-8g exhibits potent in vivo anti-inflammatory activity. Sci. Rep. 14, 4:4372.\r
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Liu, J., Gaj, T., Patterson, J. T., Sirk, S. J. and Barbas, C. F., III (2014) Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering. PLoS One 9, e85755.\r
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Liu, J., Cropp, T. A. (2013) Rational protein sequence diversification by multi-codon scanning mutagenesis. in Methods in Molecular Biology (Walker, J. M. Eds.), 978, pp. 217-218, Humana Press, Totowa.\r
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Liu, J. and Cropp, T. A. (2012) Experimental methods for scanning unnatural amino acid mutagenesis, in Methods in Molecular Biology (Pollegioni, L. and Servi, S., Eds.), 794, pp. 187-197, Humana Press, Totowa.\r
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Liu, J. and Cropp, T. A. (2012) A method for multi-codon scanning mutagenesis of proteins based on asymmetric transposons. Protein Eng. Des. Sel. 25, 67-72.\r
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Castaneda, C. A., Liu, J., Chaturvedi, A., Urszula, N., Cropp, T. A. and Fushman, D. (2011) Nonenzymatic assembly of natural polyubiquitin chains of any linkage composition and isotopic labeling scheme. J. Am. Chem. Soc., 133, 17855-17868.\r
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Castaneda, C. A., Liu, J., Kashyap, T. R., Singh, R. K., Fushman, D. and Cropp, T. A. (2011) Controlled enzymatic synthesis of natural-linkage, defined-length polyubiquitin chains using lysines with removable protecting groups. Chem. Commun. 47, 2026-2028.\r
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Liu, J., Castaneda, C. A., Wilkins, B. J., Fushman, D. and Cropp, T. A. (2010) Condensed E. coli cultures for highly efficient production of proteins containing unnatural amino acids. Bioorg. Med. Chem. Lett. 20, 5613-5616.\r
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Wilkins, B. J., Marionni, S., Young, D. D., Liu, J., Wang, Y., Di Salvo, M. L., Deiters, A. and Cropp, T. A. (2010) Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise. Biochemistry 49, 1557-1559.\r
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Chen, D., Liu, J., Liu, J. and Chen, X. (2010) Evolution of the catalytic activity of Arabidopsis thaliana glutathione transferase zeta class-1 by saturation mutagenesis. Biosci. Biotechnol. Biochem. 74, 1458-1461.\r
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Chen, X., Liu, J., Yang, P. and Chen, D. (2010) Identifying functional residues in Arabidopsis thaliana zeta class glutathione S-transferase through screening inactive point mutants. Biochemistry (Moscow) 75, 110-114.\r
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Tao, S., Chen, X., Liu, J., Ming, M., Chong, N. and Chen, D. (2008) Characterization of Ser73 in Arabidopsis thaliana glutathione S-transferase zeta class. J. Genet. Genomics 35, 507-512.\r
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Liu, J., Gaj, T., Wallen, M. C. and Barbas, C. F., 3rd (2014) Gene-free gene therapy by cell-penetrating zinc finger nuclease proteins. In ShanghaiTech-SIAIS Bioforum 2014-International Symposium on Cellular Processing of Information, Shanghai, P. R. China, November 17-21, 2014.\r
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Liu, J. and Cropp, T. A. (2010) Codon scanning mutagenesis by asymmetric transposons. In 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010.\r
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Liu, J. and Cropp, T. A. (2010) Facile codon deletion mutagenesis using asymmetric transposons. In 3rd Frontiers at the Chemistry and Biology Interface, College Park, MD, United States, May 1, 2010.\r
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Liu, J. and Cropp, T. A. (2009) Identification and characterization of fluorescent GFP mutants with internal deletions. In 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009.