个人简历

徐恒，特别研究员，博士生导师。2003年毕业于南京大学匡亚明学院物理专业，获得理学学士学位；2010年毕业于美国布朗大学，获得物理学博士学位；同年进入美国贝勒医学院从事博士后研究工作。2017年加入上海交通大学物理与天文学院。长期从事生物物理学和定量生物学方面的研究工作，致力于开发单细胞、单分子尺度的定量测量方法和理论模型以理解各种生命过程背后的定量规律。在Science, Nature Methods, Physical Review Letters等顶尖学术期刊上发表多篇论文，并获得2014年度美国Burroughs Wellcome基金会Career Awards at the Scientific Interface。目前的研究主要集中在：（1）基因调控动力学过程的定量测量和理论表征，（2）单细胞、单分子荧光显微测量技术的开发和应用。

研究领域

""1.基因调控动力学；2.单细胞、单分子荧光显微测量技术；3.神经系统发育。""""

近期论文

Heng Xu, Samuel O. Skinner, Anna M. Sokac, Ido Golding, “Stochastic Kinetics of Nascent RNA”, Physical Review Letters, 117, 128101 (2016). Leonardo A. Sepúlveda, Heng Xu, Jing Zhang, Mengyu Wang, Ido Golding, “Measurement of Gene Regulation in Individual Cells Reveals Rapid Switching Between Promoter States”, Science, 351(6278), 1218 (2016). Samuel O. Skinner, Heng Xu, Sonal N. Jaiswal, Pablo R. Freire, Thomas P. Zwaka, Ido Golding, “Single-cell analysis of transcription kinetics across the cell cycle”, Elife, 5, e12175 (2016). Heng Xu, Leonardo A. Sepúlveda, Lauren Figard, Anna M. Sokac, Ido Golding, “Combining protein and mRNA quantification to decipher transcriptional regulation”, Nature Methods, 12(8), 739 (2015). Arseny S. Khakhalin, David Koren, Jenny Gu, Heng Xu, Carlos D. Aizenman, “Excitation and inhibition in recurrent networks mediate collision avoidance in Xenopus tadpoles”, European Journal of Neuroscience, 40(6), 2948 (2014). Lauren Figard, Heng Xu, Hernan Garcia, Ido Golding, Anna M. Sokac, “The plasma membrane flattens out to fuel cell surface growth during Drosophila cellularization”, Developmental Cell 27(6), 648 (2013). Samuel O. Skinner, Leonardo A. Sepúlveda, Heng Xu, Ido Golding, “Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization”, Nature Protocols. 8(6), 1100 (2013). Heng Xu, Arseny S. Khakhalin, Arto V. Nurmikko, Carlos D. Aizenman, “Visual experience-dependent maturation of correlated neuronal activity patterns in a developing visual system”, Journal of Neuroscience. 31(22), 8025 (2011). Wei Dong, Ryan H. Lee, Heng Xu, Shelley Yang, Kara G. Pratt, Vania Cao, Yoon-Kyu Song, Arto V. Nurmikko, Carlos D. Aizenman, \