个人简历
学习经历 2004. 9-2010. 7，复旦大学，遗传学，博士 2000. 9-2004. 7，合肥工业大学，生物工程，学士 工作经历 2014. 3-至今, 上海交通大学, 系统生物医学研究院, 副研究员 2011. 8-2013.10, Mayo Clinic College of Medicine, Rochester, MN, USA, Department of Biochemistry and Molecular Biology, Postdoctoral research fellow 2011. 3-2011. 7, New York State University at Stony Brook, NY, USA, Department of Pathology, Postdoctoral research fellow
研究领域
肿瘤发生和发展的分子机制研究
近期论文
1) Q. Wang, S. Bu, D. Xin, B. Li, L. Wang and D. Lai, Autophagy Is Indispensable for the Self-Renewal and Quiescence of Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties, Oxidative Medicine And Cellular Longevity, 10.1155/2018/7010472, 2018. 2) Y- He*, Yu Zhao*, Lan Wang*, Laura R. Bohrer, Yunqian Pan, Liguo Wang, Haojie Huang, LSD1 promotes S-phase entry and tumorigenesis via chromatin co-occupation with E2F1 and selective H3K9 demethylation. Oncogene. 2018 Jan 25;37(4):534-543. Doi: 10.1038/onc.2017.353. 3) Xianbin Su*, Yi Shi*, Xin Zou*, Zhao-Ning Lu*, Gangcai Xie, Jean Y.H. Yang, Chong-Chao Wu, Xiao-Fang Cui, Kun-Yan He, Qing Luo, Yu-lan Qu, Na Wang, Lan Wang, Ze-Guang Han*. Single-cell RNA-Seq analysis reveals dynamic trajectories during mouse liver development, BMC Genomics, 2017 Dec 4;18(1):946. 4) Sheng Cheng*, Lan Wang*#, Chuanhuai Deng, Shi-Chun Du, Ze-Guang Han, ARID1A represses hepatocellular carcinoma cell proliferation and migration through lncRNA MVIH. Biochem Biophys Res Commun. 2017 Sep 9;491(1): 178-182. 5) Rui Gao, Lan Wang, Hao Cai, Jingjing Zhu, Long Yu. E3 ubiquitin ligase RLIM negatively regulates c-Myc transcriptional activity and restrains cell proliferation. PLOS ONE. 2016 Sep 29; 11(9):e0164086. 6) Bing-Hao Wu, Hui Chen, Chun-Miao Cai, Jia-Zhu Fang, Chong-Chao Wu, Li-Yu Huang, Lan Wang and Ze-Guang Han. Epigenetic silencing of JMJD5 promotes the proliferation of hepatocellular carcinoma cells by down-regulating the transcription of CDKN1A. Oncotarget. 2016 Feb 9;7(6):6847-63. 7) Lan Wang*, Xianzhuo Zeng*, Shuai Chen*, Liya Ding, Jian Zhong, Jonathan C Zhao, Liguo Wang, Aaron Sarver, Antonius Koller, Jizu Zhi, Yupo Ma, Jindan Yu, Junjie Chen and Haojie Huang#. BRCA1 is a negative modulator of the PRC2 complex. EMBO J. 2013. 32; 1584-1597. 8) Lan Wang* and Haojie Huang. EZH2 takes the stage when BRCA1 loses. Cell Cycle. 2013 Dec. 1; 12(23):3575-6. 9) Lan Wang*, Guifen He, Pingzhao Zhang, Xiang Wang, Mei Jiang, Long Yu. Interplay between MDM2, MDMX, Pirh2 and COP1-the Negative Regulators of p53. Mol Biol Rep. 2011. 38 (6): 229-36. 10) Lan Wang*, Rui Gao, Long Yu. Combined analysis of association between p73 G4C14-to-A4T14 polymorphisms and cancer risk. Mol Biol Rep. 2012. Feb; 39(2):1731-8. 11) Guifen He, Qian Wang, Yuqi Zhou, Xiaohua Wu, Lan Wang, Nadire Duru, Xiangtao Kong, Pingzhao Zhang, Bo Wan, Long Sui, Qisang Guo, Jian-Jian Li and Long Yu. 2011. YY1 is a novel potential therapeutic target for the treatment of HPV infection-induced cervical cancer by arsenic trioxide. Int J Gynecol Cancer, 21 (6): 1097-1104. 12) Qian Wang, Ying Yang, Lan Wang, Pingzhao Zhang, Long Yu. 2008. Acidic domain is indispensable for MDM2 to negatively regulate the acetylation of p53. Biochem Biophys Res Commun. 26;374(3): 437-41.
