个人简历

学习经历 2008/9 - 2012/12，香港大学，微生物学，博士 2004/9 - 2008/7，中国科学技术大学，生物科学，学士 工作经历 2014/6 - 至今，上海交通大学，系统生物医学研究院 2012/12 - 2014/3，Fluidigm，Field Application Specialist

研究领域

""单细胞生物学； 肝癌遗传学及表观遗传学；""""

近期论文

1. Xianbin Su*#, Yi Shi*, Ruihong Li*, Zhao-Ning Lu*, Xin Zou, Jiao-Xiang Wu, Ze-Guang Han. Application of qPCR assays based on haloacids transporter gene dehp2 for discrimination of Burkholderia and Paraburkholderia. (BMC Microbiology, 2019, 19:36) 2. Xianbin Su*, Yi Shi*, Xin Zou*, Zhao-Ning Lu*, Gangcai Xie, Jean Y.H. Yang, Chong-Chao Wu, Xiao-Fang Cui, Kun-Yan He, Qing Luo, Yu-lan Qu, Na Wang, Lan Wang, Ze-Guang Han#. Single-cell RNA-Seq analysis reveals dynamic trajectories during mouse liver development. (BMC Genomics, 2017, 18:946) 3. Xianbin Su#, Ruihong Li, Ka-Fai Kong, Jimmy S. H. Tsang#. Transport of haloacids across biological membranes. (Biochimica et Biophysica Acta, 2016, 1858: 3061-3070) 4. Xianbin Su#, Ruihong Li, Jimmy S. H. Tsang#. The 228 bp upstream non-coding region of haloacids transporter gene dehp2 has regulated promoter activity. (Gene, 2016, 593: 322-329) 5. Xianbin Su, Liyu Deng, Ka Fai-Kong, Jimmy S. H. Tsang#. Enhanced degradation of haloacid by heterologous expression in related Burkholderia species. (Biotechnology and Bioengineering, 2013, 110: 2687–2696) 6. Xianbin Su, Jimmy S. H. Tsang#. Existence of a robust haloacids transport system in a Burkholderia species bacterium. (Biochimica et Biophysica Acta, 2013, 1828: 187-192) 7. Xianbin Su, Ka-Fai Kong, Jimmy S. H. Tsang#. Transports of acetate and haloacetate in Burkholderia species MBA4 are operated by distinct systems. (BMC Microbiology, 2012, 12:267) 8. Yingxin Lin, Shila Ghazanfar, Kevin Y. X. Wang, Johann A. Gagnon-Bartsch, Kitty K. Lo, Xianbin Su, Ze-Guang Han, John T. Ormerod, Terence P. Speed, Pengyi Yang, Jean Yee Hwa Yang. scMerge leverages factor analysis, stable expression, and pseudoreplication to merge multiple single-cell RNA-seq datasets. (PNAS, 2019, doi: https://doi.org/10.1073/pnas.1820006116) 9. Qian Shi, Fei Zhuang, Ji-Ting Liu, Na Li, Yuan-Xiu Chen, Xian-Bin Su, Ai-Hong Yao, Qing-Ping Yao, Yue Han, Shan-Shan Li, Ying-Xin Qi, Zong-Lai Jiang. Single-cell analyses reveal functional classification of dendritic cells and their potential roles in inflammatory disease. (FASEB J. 2019, 33(3): 3784-3794) 10. Yuchen Yuan, Yi Shi, Xianbin Su, Xin Zou, Qing Luo, David Dagan Feng, Weidong Cai, Ze-Guang Han. Cancer type prediction based on copy number aberration and chromatin 3D structure with convolutional neural networks. (BMC Genomics, 2018, 19 (Suppl 6):4919) 11. Yu-Jun Dai, Yue-Ying Wang, Jin-Yan Huang, Li Xia, Xiao-Dong Shi, Jie Xu, Jing Lu, Xian-Bin Su, Ying Yang, Wei-Na Zhang, Pan-Pan Wang, Song-Fang Wu, Ting Huang, Jian-Qing Mi, Ze-Guang Han, Zhu Chen, Sai-Juan Chen. Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement. (PNAS, 2017, 114:5237-5242) 12. Yi Shi*,Xian-Bin Su*, Kun-Yan He, Bing-Hao Wu, Bo-Yu Zhang, Ze-Guang Han. Chromatin accessibility contributes to simultaneous mutations of cancer genes. (Scientific Reports, 2016, 6:35270)