个人简历

金卫林,男,医学博士，上海交通大学国家转化医学中心、纳米生物医学工程研究所副研究员。1994年，毕业于武汉大学生物化学专业，获学士学位后应招入伍。进入第四军医大学全军神经科学研究所任助教。2004年，师从著名神经生物学家鞠躬院士获医学博士学位。2005年底转业人才引进到上海交通大学，被聘为上海交通大学副研究员。 教育经历 1. 2001/08-2004/06, 第四军医大学，基础医学部，博士，导师：鞠躬 2. 1998/09-2001/06, 第四军医大学，基础医学部，硕士，导师：鞠躬 3. 1990/09-1994/07,武汉大学，生物系生化专业，学士 工作经历 2015/01-至今，上海交通大学，电子信息与电气工程学院，副研究员 2005/12-2014/12，上海交通大学，生命科学技术学院，副研究员 2004/07-2005/11,第四军医大学，基础医学部，讲师 1994/07-1998/08, 第四军医大学，基础医学部，助教

研究领域

转化神经科学，肿瘤分子治疗和免疫治疗基础

近期论文

Gao J, Ma Y, Fu HL, Luo Q, Wang Z, Xiao YH, Yang H, Cui DX and Jin WL*. Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells. Protein Cell. 2016 May; 7(5):351-61. Mao XY*, Dai JX, Zhou HH, Liu ZQ*, Jin WL*.Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future. Oncotarget. 2016 Mar 14. doi: 10.18632/oncotarget.8075. [Epub ahead of print] Mao XY*, Tokay T, Zhou HH, Jin WL*. Long-range and short-range tumor-stroma networks synergistically contribute to tumor-associated epilepsy. Oncotarget. 2016 Mar 7. doi: 10.18632/oncotarget.7962. [Epub ahead of print] Review. Lin XB#, Jiang L#, Ding MH, Chen ZH, Bao Y, Chen Y, Sun W, Zhang CR, Hu HK, Cai Z, Lu CY, Zhou JY, Qian J, Wu XJ, Jin WL*, Hu GH*. Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells. Tumour Biol. 2016 Mar;37(3):2901-8. Li L, Deng B, Wang S, Zhong H, Liu Z, Jin W, Jiang T, Xiao Z, Wang Q. synchronous therapy targeting Nogo-A enhances neurobehavioral recovery by reducing neuronal loss and promoting neurite outgrowth after cerebral ischemia in mice. J Drug Target. 2016;24(1):13-23. Xu CJ*.#, Wang JL#, Jin WL*. The Emerging Therapeutic Role of NGF in Alzheimer's Disease. Neurochem Res. 2016 Jan 22. [Epub ahead of print] Dai Jinxiang, Bercury Kathryn, Jin Weilin and Macklin Wendy*. Olig1 acetylation and nuclear export mediate oligodendrocyte development. The Journal of Neuroscience, December 2, 2015, 35(48):15875–15893. Wang B, Ma A, Zhang L, Jin WL, Qian Y, Xu G, Qiu B, Yang Z, Liu Y, Xia Q, Liu Y. POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.Nat Commun. 2015 Oct 29;6:8704. doi: 10.1038/ncomms9704. Li C, Ruan J, Yang M, Pan F, Gao G, Qu S, Shen YL, Dang YJ, Wang K, Jin WL, Cui DX*. Human induced pluripotent stem cells labeled with fluorescent magnetic nanoparticles for targeted imaging and hyperthermia therapy for gastric cancer. Cancer Biol Med. 2015 Sep;12(3):163-74. doi: 10.7497/j.issn.2095-3941.2015.0040. Mi, Y#.; Gao, X#.; Dai, J.; Ma, Y.; Xu, L*.; Jin, W*. A Novel Function of TET2 in CNS: Sustaining Neuronal Survival. Int. J. Mol. Sci. 2015, 16, 21846-21857. Ding MH#, Wang Z#, Jiang L#, Fu HL, Gao J, Lin XB, Zhang CL, Liu ZY, Shi YF, Qiu GZ, Ma Y, Cui DX, Hu GH*, Jin WL*. The transducible TAT-RIZ1-PR protein exerts histone methyltransferase activity and tumor-suppressive functions in human malignant meningiomas. Biomaterials 2015 Jul; 56 (3): 165-178. doi: 10.1016/j.biomaterials.2015.03.058 Zhang J, Song Y, Zhang C, Zhi X, Fu H, Ma Y, Chen Y, Pan F, Wang K, Ni J, Jin W, He X*, Su H*, Cui D*. Circulating MiR-16-5p and MiR-19b-3p as Two Novel Potential Biomarkers to Indicate Progression of Gastric Cancer. Theranostics 2015; 5(7):733-745. doi:10.7150/thno.10305. Xu CJ*, Wang JL, Jin WL*. The Neural Stem Cell Microenvironment: Focusing on Axon Guidance Molecules and Myelin-Associated Factors. J Mol Neurosci. 2015 Mar 11. [Epub ahead of print] Zhang C, Zhou Z, Zhi X, Ma Y, Wang K, Wang Y, Zhang Y, Fu H, Jin W, Pan F, Cui D. Insights into the Distinguishing Stress-induced Cytotoxicity of Chiral Gold Nanoclusters and the Relationship with GSTP1. Theranostics 2015; 5(2):134-149. doi:10.7150/thno.10363. Mi, Y. #*, Gao, X#., Ma, Y., Gao, J., Wang, Z., and Jin, W.L.* A novel centrosome and microtubules associated subcellular localization of Nogo-A: implications for neuronal development, International Journal of Biochemistry and Cell Biology. 2014 December, 57:1-6 Xing-Chun Gao#*, Ya-Jing Mi#, Yue Ma, Weilin Jin*. LEF1 regulates glioblastoma cell proliferation, migration, invasion, and cancer stem-like cell self-renewal. Tumour Biol. 2014 Nov. 35:11505–11511. Xing-Chun Gao, Weilin Jin*. The Emerging Role of Tumor-Suppressive MicroRNA-218 in Targeting Glioblastoma Stemness. Cancer Lett. 2014 Oct 10; 353(1):25-31. doi: 10.1016/j.canlet.2014.07.011. Epub 2014 Jul 17. Hua-Lin Fu, Yue Ma, Lun-Gen Lu, Peng Hou, Baojie Li, Weilin Jin*, and Da-Xiang Cui*. TET1 Exerts Its Tumor Suppressor Function by Interacting with p53-EZH2 Pathway in Gastric Cancer. J. Biomed. Nanotechnol. 2014. 10, 1217-1230. Xiang-Hui Zhao#*, Jin-Xiang Dai#, Yue Ma, Ya-Jing Mi, Daxiang Cu, Gong Ju, Wendy B. Macklin, Weilin Jin*. Dynamics of Tet hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation. Glia. 2014; 62(6):914-26. Yun-Kai Dai#, Yue Ma #, Keng Chen #, Ya-Jing Mi, Hua-Lin Fu, Da-Xiang Cui and Weilin Jin*. A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1. Mol Cell Neurosci. 2014, 60: 10-25.