个人简历

学习经历 1998/09 – 2002/06，华东理工大学，生物工程学院生物化工系，工学学士 2002/09 – 2007/06，华东理工大学，生物工程学院生物化工系，生物反应器工程国家重点实验室，工学博士 工作经历 2007/08 – 2008/09，新加坡国立大学，生物科学系，博士后 2008/10 – 2010/11，上海交通大学，系统生物医学研究院，博士后 2010/12 –2014/12，上海交通大学，系统生物医学研究院，助理研究员 2015/01 – 至今，上海交通大学，系统生物医学研究院，副研究员

研究领域

分子遗传学，三维基因组转录调控，药物基因组学，药物毒理与代谢

近期论文

Wang L., Huang H. #, Wu, Q. # (2017)The diversity of DNA fragment editing by CRISPR/Cas9 in highly homologous or repetitive sequences. Yichuan. 39(4):313-325 Chen D., Zuo Y., Zhang X., Ye Y., Bao X., Huang H., Tepakhan W., Wang L., Ju J., Chen G., Zheng M., Liu D., Huang S., Zong L., Li C., Chen Y., Zheng C., Shi L., Zhao Q., Wu Q., Fucharoen S., Zhao C. #, and Xu X. # (2017) A genetic variant ameliorates beta-thalassemia severity by epigenetic-mediated elevation of human fetal hemoglobin expression. American Journal of Human Genetics. 101(1):130-138 Huang H. and WU, Q.# (2016) CRISPR double cutting through the labyrinthine architecture of 3D genomes. J Genet Genomics. 43:273-88 Zhao B., Huang P., Rong P., Wang Y., Gao M., Huang H., Sun K., Chen X., Li W. (2016) Facile synthesis of ternary CdMnS QD-based hollow nanospheres as fluorescent/magnetic probes for bioimaging. Journal of Materials Chemistry B. 4(7): 1208-12. Wang Y.*, Huang H.*, Wu, Q. (2014) Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases. Molecular Pharmacology. 86(1):62-75（* Co-first author） Yang J., Cai L., Huang H., Liu B., Wu, Q. (2012) Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population. PLoS One 7: e33988. Huang, H., WU, Q. (2010). Cloning and comparative analyses of the zebrafish Ugt repertoire reveal Its evolutionary diversity. PLoS One 5: e9144 Huang H., Yu Y., Yi X., Zhang Y. (2007) Nitrogen metabolism of asparagine and glutamate in Vero cells studied by 1H/15N NMR spectroscopy. Applied Microbiology and Biotechnology. 77: 427-436 Huang H., Yi X., Zhang Y. (2006) Improvement of Vero cell growth in glutamate-based culture by supplementing ammoniagenic compounds. Process Biochemistry. 41: 2386-2392