个人简历

200108-200507:湖南农业大学本科 学习\r
200509-201101:中国农业大学硕博连读 学习\r
200709-200812:美国德克萨斯大学加尔维斯敦医学分部联合培养博士 学习\r
200901-200909:美国德克萨斯大学休斯顿健康科学中心联合培养博士 学习\r
201108- :首都医科大学 任职

研究领域

"""""阿尔茨海默病动物模型研制、基础及转化医学研究"

近期论文

Wu Y#, Zhang J#, Peng B, Tian D, Zhang D, Li Y, Feng X, Liu J, Li J, Zhang T, Liu X, Lu J, Chen B*, Wang S*.Generating viable mice with heritable embryonically lethal mutations using the CRISPR-Cas9 system in two-cell embryos. Nature Communications. 2019,10(1):2883.SCI\r
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Zhang J#, Chen B#, Lu J, Wu Y, Wang S, Yao Z, Zhu L, Qiao Y, Sun Q, Qin W, Zhao Q, Jia J, Wei C*.Brains of rhesus monkeys display Aβ deposits and glial pathology while lacking Aβ dimers and other Alzheimer's pathologies. Aging Cell. 2019,18(4):e12978.SCI\r
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Zhang X, Hou Y, Peng C, Wang C, Wang X, Liang Z*, Lu J, Chen B*, Dai J, Liu B, Cui M*.Oligoethyleneoxy-Modified 99mTc-Labeled β-Amyloid Imaging Probes with Improved Brain Pharmacokinetics for Single-Photon Emission Computed Tomography. J Med Chem. 2018,61(3):1330-1339.SCI\r
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Zhao Q#, Lu J#, Yao Z, Wang S, Zhu L, Wang J, Chen B*.Upregulation of Aβ42 in the Brain and Bodily Fluids of Rhesus Monkeys with Aging. J Mol Neurosci. 2017,61(1):79-87.SCI\r
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Zhang X, Yu P, Yang Y, Hou Y, Peng C, Liang Z*, Lu J, Chen B*, Dai J, Liu B, Cui M*.99mTc-Labeled 2-Arylbenzothiazoles: Aβ Imaging Probes with Favorable Brain Pharmacokinetics for Single-Photon Emission Computed Tomography. Bioconjug Chem. 2016,27(10):2493–2504.SCI\r
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Chen B, Soto C, Morales R*.Peripherally administrated prions reach the brain at sub-infectious quantities in experimental hamsters. FEBS Lett. 2014,588(5):795-800.SCI\r
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Chen B, Morales R, Barria MA, Soto C*.Estimating prion concentration in fluids and tissues by quantitative PMCA. Nature Methods. 2010,7(7):519-520.SCI