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肖敏
2023-05-12 14:57
  • 肖敏
  • 肖敏 - 教授 博导-山东大学-微生物技术国家重点实验室-个人资料

近期热点

资料介绍

个人简历


教育背景: 博士 1996.9-2000.6 山东大学 微生物学 硕士 1985.9-1988.6 山东大学 微生物学 本科 1981.9-1985.9 山东大学 微生物学 工作经历: 2001-今 教授,博士生导师, 山东大学 微生物技术国家重点实验室&国家糖工程技术研究中心 1996-2000 副教授, 山东大学 微生物技术国家重点实验室 1988-1995 助教及讲师, 山东大学微生物系 2003 美国Wayne State Univ访问学者 1997-1998 日本京都大学(Kyoto Univ)UNESCO微生物学高级研修

研究领域


主要集中在生物催化与生物合成方面,现今重点开展酶催化的糖基化作用研,也同时关注真菌的尼古丁代谢及光合细菌的类胡萝卜素合成研究。

近期论文


1. Xiaodi Chen, Li Xu, Lan Jin, Bin Sun, Guofeng Gu, Lili Lu*,Min Xiao*.Efficient and regioselective synthesis of β-GalNAc/GlcNAc-lactose by a bifunctional transglycosylating β-N-acetylhexosaminidase from Bifidobacterium bifidum. Appl Environ Microbiol. 2016, 82(18):5642-5652. 2. Li Xu, Xiaohong Liu, Zhenhao Yin, Qian Liu, Lili Lu,Min Xiao*.Site-directed mutagenesis of α-L-rhamnosidase from Alternaria sp. L1 to enhance synthesis yield of reverse hydrolysis based on rational design. Appl Microbiol Biotechnol. 2016, 100(24):10385-10394. 3. Wei Gong,Li Xu,Guofeng Gu,Lili Lu,Min Xiao*. Efficient and regioselective synthesis of globotriose by a novel α-galactosidase from Bacteroides fragilis. Appl Microbiol Biotechnol 2016,100: 6693–6702. 4. Lijuan Xu, Tingting Qi, Li Xu, Lili Lu* &Min Xiao*. Recent progress in the enzymatic glycosylation of phenolic compounds. Journal of Carbohydrate Chemistry. 2016, 35(1):1-23. 5. Jie Zhang, Lili Lu, Li Lu, Yang Zhao, Liping Kang, Xu Pang, Jingyuan Liu, Tengchuan Jiang, Min Xiao*, Baiping Ma*. Galactosylation of steroidal saponins by β-galactosidase from Lactobacillus bulgaricus L3. Glycoconj J. Glycoconj J. 2016, 33(1):53-62. 6. Shuquan Fan, Huaqin Zhang, Xiaodi Chen, Lili Lu, Li Xu andMin Xiao*. Cloning, characterization, and production of three -L-fucosidases from Clostridium perfringens ATCC 13124. J Basic Microbiol. 2015, 55(4), 347-357. 7. Lili Lu, Qian Liu, Lan Jan, Zhenghao Yin, Li Xu,Min Xiao*. Enzymatic synthesis of rhamnose containing chemicals by reverse hydrolysis. PLoS One. 2015, 10(10):e0140531. 8. Lili Lu, Yuchuan Guo, Lijuan Xu, Tingting Qi, Lan Jin, Li Xu,Min Xiao*. Galactosylation of caffeic acid by an engineered β-galactosidase. Drug Discoveries & Therapeutics. 2015; 9(2):123-128. 9. Lili Lu, Lijuan Xu, Yuchuan Guo, Dayu Zhang, Tingting Qi, Lan Jin, Guofeng Gu, Li Xu,Min Xiao*. Glycosylation of Phenolic Compounds by the Site-Mutated β-Galactosidase from Lactobacillus bulgaricus L3. PLoS ONE. 2015, 10(3): e0121445. 10. Lili Zhang, Lili Lu, Shuquan Fan, Lan Jin, Guofeng Gu, Li Xu andMin Xiao*. One-step synthesis of -Gal epitope and globotriose derivatives by an engineered -galactosidase. RSC Advances, 2015, 5, 22361 – 22364. 11. Li Xu, Dongxue Wang, Lili Lu, Lan Jin, Jiawei Liu, Deyong Song, Zhongwu Guo,Min Xiao*. Purification, Cloning, Characterization, and N-Glycosylation Analysis of a Novel -Fructosidase from Aspergillus oryzae FS4 Synthesizing Levan- and Neolevan-Type Fructooligosaccharides. PLoS ONE. 2014, 9(12): e114793. 12. Lili Lu, Feng Fu, Renfei Zhao, Lan Jin, Chunjuan He, Li Xu,Min Xiao*. A recombinant levansucrase from Bacillus licheniformis 8-37-0-1catalyzes versatile transfructosylation reactions. Process Biochem. 2014, 49: 1503-1510.

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