个人简历

教育背景 博士：1996.9-2000.7；华中农业大学；生物化学与分子生物学 硕士：1989.9-1992.7；中国科学院武汉病毒研究所；动物病毒学 学士：1985.9-1989.7；山东师范大学；普通生物学 工作经历 起止时间 单位名称 专业技术职务 2009.3-至今山东大学 教授 2004.3-2009.12University of Texas Health Science Center at Tyler(USA) Instructor,Research associate senior, Post-doc. 2001.5-2004.2University of Nancy I(France), Post-doc

研究领域

1. 放线菌的细胞分裂、形态发育、及初级与次级代谢的调控 2. 微生物与宿主的关系 3 . 海洋微生物的酶学

近期论文

1. Zhu Y, Zhang P, Zhang J, Xu W, Wang X, Wu L, Sheng D, Ma W, Cao G, Lu Y, Chen X, andPang X*. 2019. The developmentalregulatorMtrA binds GlnR boxes and represses nitrogen metabolism genes inStreptomyces coelicolor(Submitted). 2. Liu M, Zhang P, Zhu Y, Lu T, Wang Y, Cao, G, Shi M, Chen X, Tao M, andPang X*.2019.Novel Two-Component system MacRS is a pleiotropic regulator that controls multiple morphogenic membrane protein genes inStreptomyces coelicolor.Applied and Environmental Microbiology85 (4):1-23. 3. Lu T, Zhu Y, Zhang P, Sheng D, Cao G,Pang X*. 2018. SCO5351 is a pleiotropic factor that impacts secondary metabolism and morphological development inStreptomyces coelicolor.FEMS Microbiol Lett365 (17). 4.Zhang P, Wu L, Zhu Y, Liu M, Wang Y, Cao G, Chen XL, Tao M,Pang X*.2017.Deletion of MtrA Inhibits Cellular Development ofStreptomyces coelicolorand Alters Expression of Developmental Regulatory genes.Frontiers in Microbiology8(2013):1-18. 5.Cao G, Zhang P, Gu Y,Pang X*. 2017.Gene Over expression inStreptomyces hygroscopicusAssociated with DNA amplification.Current Microbiology74:979-86. 6. Zhao Z, Shi T, Xu M, Brock NL, Zhao YL, Wang Y, Deng Z,Pang X*, Tao M*. 2016.Hybrubins: Bipyrrole Tetramic Acids Obtained by Crosstalk between a Truncated Undecylprodigiosin Pathway and Heterologous Tetramic Acid Biosynthetic Genes.Organic LETTERS18(3):572-5. 7. Cao G, Howard ST, Zhang P, Wang X, Chen XL, Samten B, andPang X*. 2015.EspR, a regulator of the ESX-1 secretion system inMycobacterium tuberculosis,is directly regulated by the two-component systemsMprAB and PhoPR.Microbiology161:477-489. 8. Zhang P, Zhao Z, Li H, Chen XL, Deng Z, Bai L, andPang X*. 2015.Production of the antibiotic FR-008/Candicidin inStreptomycessp. FR-008 is coregulated by two regulators, FscRI and FscRIV, from different transcription factor families.Microbiology161:539-552. 9. Zhang P, Wu H, Chen XL, Deng Z, Bai L, andPang X*. 2014. Regulation of the Biosynthesis of Thiopeptide Antibiotic Cyclothiazomycin by a Transcriptiona1 Regulator SHJG8833 inStreptomyces hygroscopicus5008.Microbiology160:1379-1392. 10. Cao G, Howard ST, Zhang P, Hou G, and Pang X*. 2013. Functional analysis of the EspR binding sites upstream ofespRinMycobacterium tuberculosis. Current Microbiology67:572-579. 11.Pang X*, Samten B, Cao G, Wang X, Tvinnereim A, Chen X, and Howard ST. 2013. MprAB regulates theespAoperon inMycobacterium tuberculosis, and modulates ESX-1 function and host cytokine response.Journal of Bacteriology195:66-75. 12.Pang X, Howard ST. 2007. Regulation of the alpha-crystallin gene acr2 by the MprAB two-component system ofMycobacterium tuberculosis.Journal of Bacteriology189:6213-21. 13.Pang X, Vu P, Byrd TF, Ghanny S, Soteropoulos P, Mukamolova GV, 5.Wu S, Samten B, Howard ST. 2007. Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant ofMycobacterium tuberculosis.Microbiology153:1229-42. 14. Aigle B†,Pang X†, Decaris B, Leblond P. 2005. Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the dupliated type II polyketide synthase alp gene cluster inStreptomyces ambofaciens.Journal of Bacteriology187:2491-500. 15.Pang X, Aigle B, Girardet JM, Mangenot S, Pernodet JL, Decaris B, Leblond P. 2004. Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of theStreptomyces ambofacienslinear chromosome.Antimicrobial Agents and Chemotherapy48:575-88. 16.Pang X, Zhou X, Sun Y, Deng Z. 2002.Physical map of the linear chromosome ofStreptomyces hygroscopicus10-22 deduced by analysis of overlapping large chromosomal deletions.Journal of Bacteriology184:1958-65.