个人简历

教育背景 博士 起止时间：1999.9-2004.7 毕业院校：山东大学 专业：微生物学 学士 起止时间：1995.9-1999.7 毕业院校：山东大学 专业：微生物学 工作经历 起止时间 单位名称 专业技术职务 2004.7-迄今，讲师／副教授／教授，山东大学，微生物技术国家重点实验室 2004.9-2004.12，援疆教师，喀什师范大学，生命环境科学系 2008.10-2011.9，访问学者/博士后，美国加州大学洛杉矶分校，牙医学院，口腔生物学系

研究领域

主要研究细菌形成生物被膜（Biofilms）过程中复杂细胞行为的分子机制：

近期论文

1. Feng Wang#, Qing He#, Jia Yin, Sujuan Xu, Wei Hu*, Lichuan Gu*. BrlR fromPseudomonas aeruginosais a receptor for both cyclic di-GMP and pyocyanin, Nature Communications, 2018. (in press, *共同通讯) 2. Hu W#, Huang XS#, Wu JF, Yang L, Zheng YT, Shen YM, Li ZY, Li X*. Discovery of Novel Topoisomerase II Inhibitors by Medicinal Chemistry Approaches,J Med Chem，2018 Jun 20. (共同第一) 3. Wei Hu#, Maxsim L. Gibiansky#, Jing Wang, Chuandong Wang, Renate Lux, Yuezhong Li, Gerard C. L. Wong∗, Wenyuan Shi∗. Interplay between type IV pili activity and exoploysaccharides secretion 
 control motility selection in single cells ofMyxococcus xanthus, Scientific Reports, 2016, 6:17790. (#共同第一) 4. Ying Chen, Shiheng Liu, Cuilan Liu，Yan Huang, Kaikai Chi, Tiantian Su, Deyu Zhu, Jin Peng, Zhijie Xia, Jing He, Sujuan Xu, Wei Hu*, Lichuan Gu*.Dcsbis (PA2771) fromPseudomonas aeruginosa is a highly active diguanylate cyclase with unique activity regulation,Scientific Reports, 2016, 6:29499. (*共同通讯) 5. Qiao-Hong Xia#, Wei Hu#, Chen Li, Ji-Feng Wu, Liang Yang, Xue-Mei Han, Yue-Mao Shen, Zhi-Yu Li, Xun Li*.Design, synthesis, biological evaluation and molecular docking study on peptidomimetic analogues of XK469,European Journal of Medicinal Chemistry,2016, 124, 311-325. (#共同第一) 6. Tan Z, Li H, Pan H, Zhou X, Liu X, Luo N, Hu W*, Li Y. Characterization of four type IV pilin homologues inStigmatella aurantiaca DSM17044 by heterologous expression inMyxococcus xanthus. PloS One, 2013, 8:e75105. 7. Hu W#, Chen S#, Zhang R, Lin Y*. Single nucleotide polymorphisms in the upstream regulatory region alter the expression of myostatin. In vitro Cellular & Ddevelopmental Biology- Animal, 2013, 49:417-423. (#共同第一) 8. Maxsim Gibiansky, Wei Hu, Karin Dahmen, Wenyuan Shi, Gerard Wong∗.Earthquake-like dynamics inMyxococcus xanthus social motility,Proc. Natl. Acad. Sci. U S A, 2013, 110, 2330-5. 9. Hu, W., L. Li, S. Sharma, J. Wang, I. McHardy, R. Lux, Z. Yang, X. He, J.K. Gimzewski, Y. Li and W. Shi∗. 2012 DNA builds and strengthens the reticulated extracellular matrix inMyxococcus xanthus by interacting with exopolysaccharides.PLoS One, 2012,7(12): e51905. 10. H. Li∗, M. Ma, S. Luo,R. Zhang, P. Han, W. Hu∗,Metabolic responses to ethanol inSaccharomyces cerevisiaeusing a gas chromatography tandem mass spectrometry-based metabolomics approach.Int. J. Biochem. Cell Biol.,2012, 44, 1087-96. (*共同通讯) 11. W. Hu, J. Wang, I. McHardy, R. Lux, Zhe. Yang, Y. Li, W. Shi∗, Effects of Exopolysaccharide Production on Liquid Vegetative Growth, Stress Survival and Stationary Phase Recovery inMyxococcus xanthus.J. Microbiology. 2012, 50, 241-48. 12. X. He#, W. Hu#, Christopher W. Kaplan, Lihong Guo, Wenyuan Shi , Renate Lux* Adherence toStreptococci facilitates Fusobacterium nucleatum integration into an oral microbial community, Microb Ecol. 2012, 63(3),532-42.(#共同第一) 13. W. Hu#, Z. Yang#, R. Lux, M. Zhao, J. Wang, X. He & W. Shi, (2012) Direct visualization of the interaction between pilin and exopolysaccharides ofMyxococcus xanthus with eGFP-fused PilA protein. FEMS. Microbiol. Lett. 2012,326: 23-30. (#共同第一) 14. W. Hu, M. Hossain, R. Lux, J. Wang, Z. Yang, Y. Li & W. Shi∗, Exopolysaccharide-independent social motility ofMyxococcus xanthus. PLoS One, 2011, 6: e16102. 15. X. He#, W. Hu#, J. He, L. Guo, R. Lux & W. Shi∗, (2011) Community-based interference against integration ofPseudomonas aeruginosa into human salivary microbial biofilm. Mol. Oral. Microbiol., 2011,26: 337-352. (#共同第一) 16. J. Wang#, W. Hu#, R. Lux, X. He, Y. Li & W. Shi∗, Natural transformation ofMyxococcus xanthus. J. Bacteriol., 2011, 193: 2122-2132. (#共同第一) 17. Wei Hu et al., A High-throughput Model for Screening Anti-tumor Agents Capable of Promoting Polymerization of Tubulin in vitro, Acta Phamacologica Sinica, 2004, 25 (6), 775-782. 18. 胡玮 等，Cd[CH3O(OH)C6H3CH=N(CH2)2OH]2Br2,的合成、结构及微观二阶非线性光学系数，结构化学，2001，20（2），134。