个人简历

1. 2010/07-至今，山东大学，国家糖工程技术研究中心 任教 2. 2010/01-2011/12，山东大学药学院，师资博士后 3. 2015/09-2016/08，美国佐治亚州立大学，化学系，访问学者

研究领域

1. 均一糖胺聚糖的模块化酶法合成策略研究 2. 复杂寡糖的化学酶法合成及其应用 3. 糖核苷酸合成途径研究及规模化制备

近期论文

1. Shuang Li, Shuaishuai Wang, Xuan Fu, Xian-wei Liu, Peng George Wang, Junqiang Fang*. 2017. Sequential One-pot Multienzyme Synthesis of Hyaluronan and its Derivative. Carbohydrate Polymers, 178, 221-227. 2. Hailiang Zhu, Zhigang Wu, Madhusudhan Reddy Gadic, Shuaishuai Wang, Yuxi Guo, Garrett Edmundsc, Wanyi Guan*, Junqiang Fang*. 2017. Cation exchange assisted binding-elution strategy for enzymatic synthesis of human milk oligosaccharides (HMOs). Bioorganic & Medicinal Chemistry Letters,27(18):4285-4287. 3. Angie D. Calderon, Jun Zhou, Wanyi Guan, Zhigang Wu, Yuxi Guo, Jing Bai, Qing Li, Peng George Wang, Junqiang Fang* and Lei Li*. 2017. An enzymatic strategy to asymmetrically branched N-glycans. Organic & Biomolecular Chemistry, 15(35):7258-7262. 4. Xuan Fu, Wenjing Shang, Shuaishuai Wang, Yunpeng Liu, Jingyao Qu, Xi Chen, Peng George Wang* and Junqiang Fang*. 2017. A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications. Chemical Communications, 53, 3555-3558. 5. Yunpeng Liu, Liuqing Wen, Lei Li, Madhusudhan Reddy Gadi, Wanyi Guan, Kenneth Huang, Zhongying Xiao, Mohui Wei, Cheng Ma, Qing Zhang, Hai Yu, Xi Chen*, Peng George Wang*, Junqiang Fang*. 2016. A General Chemoenzymatic Strategy for the Synthesis of Glycosphingolipids. European Journal of Organic Chemistry, 4315-4320. 6. Liuqing Wen*, Kenneth Huang, Yuan Zheng, Junqiang Fang*, Shukkoor Muhammed Kondengaden, Peng George Wang*.2016. Two-step enzymatic synthesis of 6-deoxy-L-psicose. Tetrahedron Letters, 57: 3819–3822. 7. Liuqing Wen, Kenneth Huang, Mohui Wei, Jeffrey Meisner, Yunpeng Liu, Kristina Garner, Lanlan Zang, Xuan Wang, Xu Li, Junqiang Fang, Houcheng Zhang, Peng George Wang.2015. Facile Enzymatic Synthesis of Ketoses. Angewandte Chemie, 127(43): 12845–12849. 8. Shuaishuai Wang†, Xuan Fu†, Yunpeng Liu, Xian-wei Liu, Lin Wang, Junqiang Fang*, and Peng George Wang. 2015. Probing the roles of Conserved Residues in Uridyltransferase domain of Escherichia coli K12 GlmU by Site-directed Mutagenesis. Carbohydrate Research, 413(2): 70-74. 9. Yafei Zhai, Donglei Han, Ying Pan, Shuaishuai Wang, Junqiang Fang, Peng Wang, Xian-wei Liu*. 2015. Enhancing GDP-fucose production in recombinant Escherichia coli by metabolic pathway engineering. Enzyme and Microbial Technology, 69:38-45. 10. Yuxi Guo, Junqiang Fang, Tiehai Li, Xu Li, Cheng Ma, Xuan Wang, Peng G. Wang*. 2015. Comparing substrate specificity of two UDP-sugar pyrophosphorylases and efficient one-pot enzymatic synthesis of UDP-GlcA and UDP-GalA. Carbohydrate Research, 411:1-5. 11. Li, Tiehai; Wen, Liuqing; Williams, Adriel; Wu, Baolin; Li, Lei; Qu, Jingyao; Meisner, Jeffrey; Xiao, Zhongying; Fang, Junqiang; Wang, Peng George*. 2014. Chemoenzymatic synthesis of ADP-d-glycero-β-d-manno-heptose and study of the substrate specificity of HldE. Bioorganic & Medicinal Chemistry, 22(3): 1139-1147. 12. Junqiang Fang, Mengyang Xue, Guofeng Gu, Xian-wei Liu*, Peng George Wang. 2013. A chemoenzymatic route to synthesize unnatural sugar nucleotides using a novel N-acetylglucosamine-1-phosphate pyrophosphorylase from Camphylobacter jejuni NCTC 11168. Bioorganic & Medicinal Chemistry Letters, 23(15): 4303-4307. 13. Mengyang Xue, Wanyi Guan, Yang Zou, Junqiang Fang*, Xian-wei Liu*, Peng George Wang, Fengshan Wang. 2012 Investigation of the nucleotide triphosphate substrate specificity of Homo sapiens UDP-N-acetylgalactosamine pyrophosphorylase (AGX1). Bioorganic & Medicinal Chemistry Letters, 22 (12) 3957-3961. 14. Min Fang, Li Gu, Guofeng Gu*, Junqiang Fang. 2012 Facile Synthesis and Antitumor Activities of Timosaponin AIII and Its Analogs. Journal of Carbohydrate Chemistry, 31(3): 187-202. 15. Yafei Zhai, Min Liang, Junqiang Fang, Xiaoyue Wang, Wanyi Guan, Xian-wei Liu*, Peng Wang, Fengshan Wang. 2012. NahK/GlmU fusion enzyme: Characterization and one-step enzymatic synthesis of UDP-N-acetylglucosamine. Biotechnology Letters, 34(7): 1321-1326. 16. Wanyi Guan†, Li Cai†, Junqiang Fang†, Baolin Wu, Peng George Wang*. 2009. Enzymatic synthesis of UDP-GlcNAc/UDP-GalNAc analogs using N-acetylglucosamine 1-phosphate uridyltransferase (GlmU). Chemical Communications, (45): 6976-6978. 17. Junqiang Fang, Wanyi Guan, Li Cai, Guofeng Gu*, Xianwei Liu*, Peng George Wang. 2009. Systematic study on the broad nucleotide triphosphate specificity of the pyrophosphorylase domain of the N-acetylglucosamine-1-phosphate uridyltransferase from Escherichia coli K12. Bioorganic & Medicinal Chemistry Letters, 19(22): 6429-6432.