个人简历

2007至今：国家生物医学材料工程技术研究中心/四川大学生物材料工程研究中心，助理研究员/副研究员/研究员 2003-2006：国家生物医学材料工程技术研究中心/四川大学生物材料工程研究中心，生物医学工程、博士，导师：张兴栋 教授/中国工程院院士 2000-2003：四川工业学院材料科学与工程系，材料加工工程、硕士，导师：吴卫 教授 1994-2000：四川大渡河钢铁股份有限公司，助理工程师/工程师 1990-1994：四川工业学院金属材料科学与工程系，热加工工艺及设备、学士

研究领域

1、骨诱导性生物材料的设计与制备 2、生物材料表面/界面及其与蛋白/细胞的相互作用纳米生物材料 3、医用植入器械设计与产品研发

近期论文

1.Zhu Y, Zhang K, Zhao R, Ye X, Chen X, Xiao Z, Yang X*, Zhu X*, Zhang K, Fan Y, Zhang X. Bone regeneration with micro/nano hybrid-structured biphasic calcium phosphate bioceramics at segmental bone defect and the induced immunoregulation of MSCs. Biomaterials. 2017;147:133-44. 2.Wang J, Liu D, Guo B*, Yang X, Chen X, Zhu X*, Fan Y, Zhang X. Role of BCP ceramic-mediated secretion of signalling molecules by macrophages in migration and osteoblastic differentiation of MSCs. Acta Biomaterialia. 2017;51:447-60. 3.Chen H, Wang C, Yang X, Xiao Z, Zhu X*, Zhang K, Fan Y, Zhang X*. Construction of surface HA/TiO2 coating on porous titanium scaffolds and its preliminary biological evaluation. Materials Science & Engineering C. 2017;70:1047-56. 4.Wang C, Chen H, Zhu X*, Xiao Z, Zhang K*, Zhang X. An improved polymeric sponge replication method for biomedical porous titanium scaffolds. Materials Science & Engineering C. 2017;70:1192-9. 5.Chen X, Wang J, Chen Y, Cai H, Yang X, Zhu X*, Fan Y, Zhang X*. Roles of calcium phosphate-mediated integrin expression and MAPK signaling pathways in the osteoblastic differentiation of mesenchymal stem cells. Journal of Materials Chemistry B. 2016;4:2280-9. 6.Yuan B, Chen Y, Lin H, Song Y, Yang X, Tang H, Xie E, Hsu T, Yang X, Zhu X*, Zhang K*, Zhang X. Processing and Properties of Bioactive Surface-Porous PEKK. Acs Biomaterials Science & Engineering. 2016;2:977-86. 7.Chen Y, Wang J, Zhu X*, Tang Z, Yang X, Tan Y, Fan Y, Zhang X*. Enhanced effect of beta-tricalcium phosphate phase on neovascularization of porous calcium phosphate ceramics: In vitro and in vivo evidence. Acta Biomaterialia. 2015;11:435-48. 8.Wang J, Chen Y, Zhu X*, Yuan T, Tan Y, Fan Y, Zhang X*. Effect of phase composition on protein adsorption and osteoinduction of porous calcium phosphate ceramics in mice. Journal of Biomedical Materials Research Part A. 2014;102:4234-43. 9.Chen H, Wang C, Zhu X*, Zhang K, Fan Y, Zhang X. Fabrication of porous titanium scaffolds by stack sintering of microporous titanium spheres produced with centrifugal granulation technology. Materials Science & Engineering C. 2014;43:182-8. 10. Yang J, Chen H, Zhu X*, Vaidya S, Xiang Z*, Fan Y, Zhang X. Enhanced repair of a critical-sized segmental bone defect in rabbit femur by surface microstructured porous titanium. Journal of Materials Science-Materials in Medicine. 2014;25:1747-56. 11. Yang J, Wang J, Yuan T, Zhu X*, Xiang Z, Fan Y, Zhang X*. The enhanced effect of surface microstructured porous titanium on adhesion and osteoblastic differentiation of mesenchymal stem cells. Journal of Materials Science-Materials in Medicine. 2013;24:2235-46. 12. Wang J, Zhang H, Zhu X*, Fan H, Fan Y, Zhang X*. Dynamic competitive adsorption of bone-related proteins on calcium phosphate ceramic particles with different phase composition and microstructure. Journal of Biomedical Materials Research Part B. 2013;101B:1069-77. 13. Zhu X, Zhang H, Fan H*, Li W, Zhang X. Effect of phase composition and microstructure of calcium phosphate ceramic particles on protein adsorption. Acta Biomaterialia. 2010;6:1536-41. 14. Zhao C, Zhu X*, Yuan T, Fan H*, Zhang X. Fabrication of biomimetic apatite coating on porous titanium and their osteointegration in femurs of dogs. Materials Science & Engineering C. 2010;30:98-104. 15. Zhu X, Fan H*, Xiao Y, Li D, Zhang H, Luxbacher T, Zhang X. Effect of surface structure on protein adsorption to biphasic calcium-phosphate ceramics in vitro and in vivo. Acta Biomaterialia. 2009;5:1311-8.