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仝爱平
2023-05-12 13:18
  • 仝爱平
  • 仝爱平 - 教授 博导-四川大学-生物治疗国家重点实验室-个人资料

近期热点

资料介绍

个人简历


2016年至今,任四川大学生物治疗国家重点实验室研究员 2014年-2016年,美国哈佛大学医学院贝以迪医学中心访问学者 2010年,任四川大学生物治疗国家重点实验室副研究员 2008年,任四川大学生物治疗国家重点实验室助理研究员 2008年,获四川大学博士学位 2004年,获西南大学硕士学位 2000年,毕业于河南科技学院获学士学位

研究领域


1) 肿瘤免疫治疗分子机理与应用开发。包括免疫治疗新靶点的发现,新型抗体的研发,利用CRISPR等技术进行基因工程细胞(如T细胞)的遗传改造与抗肿瘤研发,肿瘤疫苗的抗肿瘤机理与新型疫苗的研发。2)中枢神经系统恶性肿瘤的发生分子机理与治疗。3) 细胞增生,分化,衰老,死亡等的基本生物学分子机制研究。

近期论文


1) Tang M, Wei H, Han L, Deng J, Wang Y, Yang M, Tang Y, Guo G, Zhou L*, Tong A*. Whole-genome sequencing identifies new genetic alterations in meningiomas. Oncotarget. 2017 Feb 3. doi: 10.18632/oncotarget.15043.(*并列通讯) 2) Wang Y, Deng J, Guo G, Tong A*, Peng X, Chen H, Xu J, Liu Y, You C, Zhou L*. Clinical and prognostic role of annexin A2 in adamantinomatous craniopharyngioma. J Neurooncol. 2017 Jan;131(1):21-29. (*并列通讯) 3) Yang Y, He L, Liu Y, Xia S, Fang A, Xie Y, Gan L, He Z, Tan X, Jiang C, Tong A*, Song X*. Promising Nanocarriers for PEDF Gene Targeting Delivery to Cervical Cancer Cells Mediated by the Over-expressing FRα. Sci Rep. 2016 Aug 31;6:32427. (*并列通讯) 4) Yuan Z*, Guo W, Yang J, Li L, Wang M, Lei Y, Wan Y, Zhao X, Luo N, Cheng P, Liu X, Nie C, Peng Y, Tong A*, Wei Y. PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells. J Biol Chem. 2015 Jun 12;290(24):14927-44. (*并列通讯) 5) Yang M, Tang M, Ma X, Yang L, He J, Peng X, Guo G, Zhou L, Luo N, Yuan Z*, Tong A*. AP-57/C10orf99 is a new type of multifunctional antimicrobial peptide. Biochem Biophys Res Commun. 2015 Feb 13;457(3):347-52. (*并列通讯) 6) Liu S, Zhou R, Zhong J, Nie C, Yuan Z, Zhou L, Luo N, Wang C*, Tong A*. HepG2.2.15 as a model for studying cell protrusion and migration regulated by S100 proteins. Biochem Biophys Res Commun. 2014 Jun 20;449(1):175-81. (*并列通讯) 7) Li Z, Tang M, Ling B, Liu S, Zheng Y, Nie C, Yuan Z, Zhou L, Guo G, Tong A*, Wei Y. Increased expression of S100A6 promotes cell proliferation and migration in human hepatocellular carcinoma. J Mol Med (Berl). 2014 Mar;92(3):291-303. (通讯作者) 8) Wu DM, Zhang P, Liu RY, Sang YX, Zhou C, Xu GC, Yang JL, Tong AP*, Wang CT*. Phosphorylation and changes in the distribution of nucleolin promote tumor metastasis via the PI3K/Akt pathway in colorectal carcinoma. FEBS Lett. 2014 May 21;588(10):1921-9. (*并列通讯) 9) Gong F, Peng X, Sang Y, Qiu M, Luo C, He Z, Zhao X, Tong A*. Dichloroacetate induces protective autophagy in LoVo cells: involvement of cathepsin D/thioredoxin-like protein 1 and Akt-mTOR-mediated signaling. Cell Death Dis. 2013 Nov 7;4:e913(通讯作者) 10) Zhou R, Huang W, Yao Y, Wang Y, Li Z, Shao B, Zhong J, Tang M, Liang S, Zhao X, Tong A*, Yang J*. CA II, a potential biomarker by proteomic analysis, exerts significant inhibitory effect on the growth of colorectal cancer cells. Int J Oncol. 2013 Aug;43(2):611-21(*并列通讯) 11) Zhang D, Tong A*, Zhou L, Fang F, Guo G*. Osteogenic differentiation of human placenta-derived mesenchymal stem cells (PMSCs) on electrospun nanofiber meshes. Cytotechnology. 2012 Dec;64(6):701-10. (*并列通讯) 12) Shao B, Tang M, Li Z, Zhou R, Deng Y, Nie C, Yuan Z, Zhou L, Tang M, Tong A*, Wei Y. Proteomics analysis of human umbilical vein endothelial cells treated with resveratrol. Amino Acids. 2012 Oct;43(4):1671-8. (通讯作者) 13) Peng XC, Gong FM, Zhao YW, Zhou LX, Xie YW, Liao HL, Lin HJ, Li ZY, Tang MH, Tong AP*. Comparative proteomic approach identifies PKM2 and cofilin-1 as potential diagnostic, prognostic and therapeutic targets for pulmonary adenocarcinoma. PLoS One. 2011;6(11):e27309. (通讯作者) 14) Tong A, Gou L, Lau QC, Chen B, Zhao X, Li J, Tang H, Chen L, Tang M, Huang C, Wei YQ. Proteomic profiling identifies aberrant epigenetic modifications induced by hepatitis B virus X protein. J Proteome Res. 2009 Feb;8(2):1037-46. doi: 10.1021/pr8008622. 15) Tong A, Wu L, Lin Q, Lau QC, Zhao X, Li J, Chen P, Chen L, Tang H, Huang C, Wei YQ. Proteomic analysis of cellular protein alterations using a hepatitis B virus-producing cellular model. Proteomics. 2008 May;8(10):2012-23. 16) Tong A, Zhang H, Li Z, Gou L, Wang Z, Wei H, Tang M, Liang S, Chen L, Huang C, Wei Y. Proteomic analysis of liver cancer cells treated with suberonylanilide hydroxamic acid. Cancer Chemother Pharmacol. 2008 Apr;61(5):791-802.

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