个人简历

2011年获清华大学北京协和医学院和北京生命科学研究所（NIBS）联合培养理学博士学位。2011年-2015年在Salk和加州大学旧金山分校（UCSF） 从事博士后研究工作; 2015-2016年在Sanford Burnham Prebys 医学发现研究所从事博士后研究工作。2016年受聘于四川大学生物治疗国家重点实验室，任研究员，化学生物学实验室主任。

研究领域

1，肿瘤分子机理2，蛋白质结构，功能及表观调控机制研究3，特异性靶向治疗药物靶点4，小分子药物及蛋白质药物开发。

近期论文

(1)Xiang Z#, Ren H#, Ying S Hu, Irene Coin, Jing Wei, Hu Cang & Lei Wang. Adding a New Covalent Bond to Proteins through Proximity-Enhanced Bioreactivity. Nature Methods, 2013, 10:885-888. (Recommended by Thomas Kodadek for the F1000 Faculty). #Authors contributed equally. (2)Tian Y#, Li Z#, Hu W#, Ren H#, Tian E, Zhao Y, Lu Q, Huang X, Yang P, Li X, Wang X, Kovács AL, Yu L, Zhang H. C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell, 2010, 141:1042-1055. (Previewed as a leading edge finding in the same issue of Cell by Christina McPhee and Eric Baehrecke; selected as “Exceptional” for FACULTY OF 1000 Biology; highlighted by Felix Cheung in Nature China). #Authors contributed equally. (3)Ren H, Yang B, Ma C, Hu YS, Wang PG, Wang L. Cysteine Sulfoxidation Increases the Photostability of Red Fluorescent Proteins. ACS Chem Biol, 2016, 11(10):2679-2684. (4)Ren H, Zhang H. Wnt signaling controls temporal identities of seam cells in Caenorhabditis elegans. Dev Biol, 2010, 345:144-155. (5)Alamudi SH, Satapathy R, Kim J, Su D, Ren H, Das R, Hu L, Alvarado-Martínez E, Lee JY, Hoppmann C, Peña-Cabrera E, Ha HH, Park HS, Wang L, Chang YT. Development of background-free tame fluorescent probes for intracellular live cell imaging. Nature Communications, 2016, 7: 11964. (6)Xiang Z, Lacey VK, Ren H, Xu J, Burban DJ, Jennings PA, Wang L. Proximity-enabled protein crosslinking through genetically encoding haloalkane unnatural amino acids. Angew Chem Int Ed, 2014, 53: 2190-2193.