个人简历

四川省学术与技术带头人、四川省卫计委学术带头人；在四川大学生命科学学院完成本科、硕士和博士学习后，到美国俄亥俄州立大学医学院进行博士后研究、哥伦比亚大学医学中心任Associate Research Scientist、俄亥俄州立大学癌症中心Carlo Croce院士团队任Research Scientist、及加州大学圣地亚哥分校Napoleone Ferrara院士团队工作。2014年9月回到四川大学生物治疗国家重点实验室工作

研究领域

非编码RNA在人类重大疾病中的功能及其作用机制

近期论文

1. Gou Q, Gao L, Nie X, Pu W, Zhu J, Wang Y, Liu X, Tan S, Zhou JK, Gong Y, He J, Wu K, Xie Y, Zhao W, Dai L, Liu L, Xiang R, Wei YQ, Zhang L*, Peng Y*. Long noncoding RNA AB074169 inhibits cell proliferation via modulation of KHSRP-mediated p21 expression in papillary thyroid carcinoma. Cancer Res. 2018 May 7. doi: 10.1158/0008-5472.CAN-17-3766 2. Tan S, Gou Q, Pu W, Guo C, Yang Y, Wu K, Liu Y, Liu L, Wei YQ, Peng Y*. Circular RNA F-circEA produced from EML4-ALK fusion gene as a novel liquid biopsy biomarker for non-small cell lung cancer. Cell Res. 2018 Apr 8. doi: 10.1038/s41422-018-0033-7 3. Li J, Pu W, Sun HL, Zhou JK, Fan X, Zheng Y, He J, Liu X, Xia Z, Liu L, Wei YQ, Peng Y*. Pin1 impairs microRNA biogenesis by mediating conformation change of XPO5 in hepatocellular carcinoma. Cell Death Differ. 2018 Feb 14. doi: 10.1038/s41418-018-0065-z 4. Pu W, Li J, Zheng Y, Shen X, Fan X, Zhou JK, He J, Deng Y, Liu X, Wang C, Yang S, Chen Q, Liu L, Zhang G, Wei YQ, Peng Y*.Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development. Hepatology. 2018 Jan 30. doi: 10.1002/hep.29819 5. Sun D, Zhou JK, Zhao L, Zheng ZY, Li J, Pu W, Liu S, Liu XS, Liu SJ, Zheng Y*, Zhao Y*, Peng Y*. Novel curcumin liposome modified with hyaluronan targeting CD44 plays an anti-leukemic role in acute myeloid leukemia in vitro and in vivo. ACS Appl Mater Interfaces. 2017, 9(20): 16857-16868 6. Sun HL, Cui R, Zhou J, Teng KY, Hsiao YH, Nakanishi K, Fassan M, Luo Z, Shi G, Tili E, Kutay H, Lovat F, Vicentini C, Huang HL, Wang SW, Kim T, Zanesi N, Jeon YJ, Lee TJ, Guh JH, Hung MC, Ghoshal K, Teng CM, Peng Y*, Croce CM*. ERK activation globally downregulates miRNAs through phosphorylating exportin-5. Cancer Cell. 2016, 30(5): 723-736 7. Peng Y, Dai Y, Hitchcock C, Yang X, Kassis ES, Liu L, Luo Z, Sun HL, Cui R, Wei H, Kim T, Lee TJ, Jeon YJ, Nuovo GJ, Volinia S, He Q, Yu J, Nana-Sinkam P, Croce CM*. Insulin growth factor signaling is regulated by miR-486, an underexpressed microRNA in lung cancer. Proc Natl Acad Sci USA 2013,110(37):15043-15048 8. Peng Y, Schoenberg DR*. c-Src activates endonuclease-mediated mRNA decay. Mol. Cell. 2007,25:779-787