个人简历

Postdoctoral Associate M.I.T., 2014-2015, Advisor: Stephen L. Buchwald\r
Ph.D. University of Minnesota - Twin Cities, 2013, Advisor: Thomas R. Hoye\r
M.S. University of Minnesota - Twin Cities, 2010, Advisor: Thomas R. Hoye\r
B.E. Southeast University 2006\r
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Awards and Honors\r
2014 Reaxys PhD Prize Winner\r
2017 Thieme Chemistry Journal Award

研究领域

"""""1. Site-selective modification of glycosides\r
Rapid accesses to analogues and derivatives of glycosides offer tremendous opportunities to explore and exploit the properties of these compounds. However

近期论文

Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation Chen Zhang, Hao Zuo, Ga Young Lee, Yike Zou, Qiu-Di Dang, K. N. Houk* and Dawen Niu* Nature Chemistry 2022\r
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Nonenzymatic Stereoselective S-Glycosylation of Polypeptides and Proteins Li-Qiang Wan, Xia Zhang, Yike Zou, Rong Shi, Jin-Ge Cao, Shi-Yang Xu, Li-Fan Deng, Li Zhou, Yanqiu Gong, Xiaoling Shu, Ga Young Lee, Haiyan Ren, Lunzhi Dai, Shiqian Qi, K. N. Houk, and Dawen Niu* J. Am. Chem. Soc. 2021, ASAP\r
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Stereoselective Preparation of C-Aryl Glycosides via Visible-Light-Induced Nickel-Catalyzed Reductive Cross-Coupling of Glycosyl Chlorides and Aryl Bromides Ze-Dong Mou, Jia-Xi Wang, Xia Zhang,* and Dawen Niu* Adv. Synth. Catal. 2021, 363, 3025– 3029 (Very Important Publication)\r
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Site-switchable mono-O-allylation of polyols (Selective modification of polyols, carbohydrates, and natural products) Hua Tang, Yu-Biao Tian, Hongyan Cui, Ren-Zhe Li, Xia Zhang, Dawen Niu* Nature Communications volume 11, Article number: 5681 (2020)\r
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A radical approach to make unnatural amino acids through converting C–S bonds in cysteine derivatives to C–C bonds （Functional group tolerant method of making peptide derivatives） Yingwei Wang, Li-Fan Deng, Xia Zhang*, Ze-Dong Mou, Dawen Niu* Angewandte Chemie International Edition, 2021, 60, 2155–2159\r
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Generation of Glycosyl Radicals from Glycosyl Sulfoxides and Its Use in the Synthesis of C‐linked Glycoconjugates Weidong Shang, Sheng‐Nan Su, Rong Shi, Ze‐Dong Mou, Guo‐Qiang Yu, Xia Zhang*，Dawen Niu* Angewandte Chemie International Edition, 2021, 60, 385–390\r
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Asymmetric O-propargylation of secondary aliphatic alcohols （Asymmetric propargylation of monosaccharides and natural products）Ren-Zhe Li, Da-Qi Liu, Dawen Niu* Nature Catalysis, 2020, 3, 672–680\r
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Catalytic Asymmetric Synthesis of α-Tetrasubstituted α-Trifluoromethyl Homoallylic Amines by Ir-Catalyzed Umpolung Allylation of Imines Yingwei Wang, Li-Fan Deng, Xia Zhang,* and Dawen Niu* Org. Lett. 2019, 21, 17, 6951-6956\r
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Ni-Catalyzed Suzuki-Miyaura Cross-Coupling of α-Oxo-Vinylsulfones to Prepare C-Aryl Glycals and Acyclic Vinyl Ethers Liang Gong, Hongbao Sun, Li-fan Deng, Xia Zhang, Jie Liu, Shengyong Yang, and Dawen Niu* Journal of the American Chemical Society, 2019, 141, 19, 7680-7686\r
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Ligand-controlled, transition-metal catalyzed site-selective modification of glycosides Weidong Shang, Bin He, and Dawen Niu* Carbohydrate Research, 2019, 474, 16-33 (invited review)\r
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2-Azaallyl Anions, 2-Azaallyl Cations, 2-Azaallyl Radicals, and Azomethine Ylides Shaojian Tang†, Xia Zhang†, Jiayue Sun, Dawen Niu*, and Jason J. Chruma* Chem. Rev., 2018, 118(20), 10393–10457\r
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Diastereo‐ and enantioselective propargylations of 5H‐thiazol‐4‐ones and 5H‐oxazol‐4‐ones as enabled by Cu/Zn and Cu/Ti catalysis Zhengyan Fu, Ning Deng, Sheng-Nan Su, Hongyang Li, Ren-Zhe Li, Xia Zhang, Jie Liu, and Dawen Niu* Angewandte Chemie International Edition, 2018, 57(46), 15217-15221\r
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Metal‐ and Base‐Free Room‐Temperature Amination of Organoboronic Acids with N‐Alkyl Hydroxylamines Hong‐Bao Sun, Liang Gong, Yu‐Biao Tian, Jin‐Gui Wu, Xia Zhang, Jie Liu, Zhengyan Fu, and Dawen Niu* Angewandte Chemie International Edition, 2018 57(30), 9456-9460\r
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Site-Selective O-Arylation of Glycosides Weidong Shang, Ze-Dong Mou, Hua Tang, Xia Zhang, Jie Liu, Zhengyan Fu, and Dawen Niu* Angewandte Chemie International Edition, 2018, 130(1), 320-324\r
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Site-Divergent Delivery of Terminal Propargyls to Carbohydrates by Synergistic Catalysis Ren-Zhe Li, Hua Tang, Liqiang Wan, Xia Zhang, Zhengyan Fu, Jie Liu, Shengyong Yang, Da Jia, and Dawen Niu* Chem 2017, 3, 834-845\r
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Iridium-Catalyzed Asymmetric Umpolung Allylation of N-Fluorenyl Imines to Prepare 1,4-Disubstituted Homoallylic Amines Liqiang Wan, Lan Tian, Jie Liu, and Dawen Niu* Synlett 2017, 28(16), 2051-2056 (invited review)\r
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Enantioselective Propargylation of Polyols and Desymmetrization of meso 1,2-Diols by Copper/Borinic Acid Dual Catalysis R-Z Li, H Tang, KR Yang, L-Q Wan, X Zhang, J Liu, Z Fu, and D Niu* Angewandte Chemie International Edition 2017, 56, 7213–7217\r
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Catalytic Asymmetric Umpolung Allylation of Imines J Liu, C-G Cao, H-B Sun, X Zhang, and D Niu* Journal of the American Chemical Society 2016, 138, 13103–13106\r
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Silver-Assisted, Iridium-Catalyzed Allylation of Bis[(pinacolato)boryl]methane Allows the Synthesis of Enantioenriched Homoallylic Organoboronic Esters M Zhan, R-Z Li, Z-D Mou, C-G Cao, J Liu*, Y Chen*, and D Niu* ACS Catal., 2016, 6, 3381–3386\r
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The Hexadehydro-Diels–Alder Cycloisomerization Reaction Proceeds by a Stepwise Mechanism T Wang, D Niu, and TR Hoye* Journal of the American Chemical Society 2016, 138 (25) 7832–7835\r