个人简历

1985年7月，医学学士，重庆医科大学；1990年7月，医学硕士，重庆医科大学；
2005年7月，医学博士，四川大学。1985年至2002年，曾经涉及临床，教学，科研和行政等领域。2005年以来，在四川大学华西基础医学与法医学院主要从事科研与教学工作。
主持和完成了包括“973”，国家自然科学基金等10余项国家、省部级科研课题。

研究领域

"包括生物医学工程，生理学与时间生物学。主要从事生物节律的产生机制，生物节律及其基因在生理和病理过程中的作用，如：代谢，肥胖，药物依赖等"

近期论文

The circadian Clock gene regulates acrosin activity of sperm through serine protease inhibitor A3K. Exp Biol Med (Maywood). 2016 Jan;241(2):205-15.
The noncircadian function of the circadian Clock gene in the regulation of male fertility. J Biol Rhythms. 2013 Jun;28(3):208-17.
Characteristics of infradian and circadian rhythms in the persistent vegetative state. J Int Med Res. 2011;39(6):2281-7.
Characteristics of circadian rhythm in patients with intracerebral hemorrhage before death. Neurosciences (Riyadh). 2011 Oct; 16(4):340-6.
Downregulation of Clock in circulatory system leads to an enhancement of fibrinolysis in mice. Exp Biol Med (Maywood). 2011 Sep; 236(9):1078-84.
The association of CLOCK gene T3111C polymorphism and hPER3 gene 54-nucleotide repeat polymorphism with Chinese Han people schizophrenics. Mol Biol Rep. 2011 Jan; 38(1): 349-54.
High expression of the circadian gene mPer2 diminishes the radiosensitivity of NIH 3T3 cells. Braz J Med Biol Res. 2009 Oct;42(10):882-91.
Behavioral change related to Wenchuan devastating earthquake in mice. Bioelectromagnetics. 2009 Dec;30(8):613-20.
Circadian blood pressure and heart rate characteristics in haemorrhagic vs ischaemic stroke in Chinese people. J Hum Hypertens. 2010 Mar;24(3):165-74.
Circadian effects on outcome following surgery for intracerebral hemorrhage in humans? Brain Res. 2009 Mar 3;1258:78-85.
High expression of circadian gene mPer2 diminishes radiosensitivity of tumor cells. Cancer Biother Radiopharm. 2008 Oct;23(5):561-70.
Telomerase reconstitution contributes to resetting of circadian rhythm in fibroblasts. Mol Cell Biochem. 2008 Jun;313(1-2):11-8.
Inhibition of tumorigenesis by intratumoral delivery of the circadian gene mPer2 in C57BL/6 mice. Cancer Gene Ther. 2007 Sep;14(9):815-8.
Laminin receptor 1: a novel protein interacting with human circadian clock protein, hPer1. Neurol Res. 2007 Jul;29(5):429-34.
Association of the 54-nucleotide repeat polymorphism of hPer3 with heroin dependence in Han Chinese population. Genes Brain Behav. 2008 Feb;7(1):26-30.
The extracellular signal-regulated kinase signaling pathway is involved in the modulation of morphine-induced reward by mPer1. Neuroscience. 2007 Apr 25;146(1):265-71.
Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal. J Circadian Rhythms. 2006 Aug 22;4:9.
Circadian gene mPer2 overexpression induces cancer cell apoptosis. Cancer Sci. 2006 Jul; 97(7): 589-96.
RACK1, a novel hPER1-interacting protein. J Mol Neurosci. 2006;29(1):55-63.
The role of mPer1 in morphine dependence in mice. Neuroscience. 2005;130(2):383-8.