巩长旸
近期热点
资料介绍
个人简历
2013年全国百篇优秀博士学位论文提名奖,2013年四川省百篇优秀博士学位论文,四川省学术和技术带头人后备人选。1999-2003年就读于四川大学生物工程专业,获理学学士学位。2005年在四川大学生物治疗国家重点实验室攻读博士学位(硕博连读),在著名肿瘤治疗学家魏于全院士的指导下完成博士论文研究工作。2010年获四川大学细胞生物学专业博士学位,同年7月起任四川大学华西医院生物治疗国家重点实验室助理研究员、副研究员、研究员。研究领域
1. 新型靶向药物和基因递送系统;2. 新型免疫佐剂;3. 纳米生物技术;4. 医用生物材料。近期论文
26. Ling Li, et al., Changyang Gong*. Multifunctional Nucleus-targeting Nanoparticles with Ultra-high Gene Transfection Efficiency for In Vivo Gene Therapy. Theranostics, 2017, 7 (6), 1633-1649. IF=8.854 25. Zichao Luo, et al., Xingyi Li*,Changyang Gong* Zhimou Yang*.A powerful CD8+ T-cell stimulating D-tetra-peptide hydrogel as a very promising vaccine adjuvant. Adv Mater, 2017, 29(5), 1601776. IF=18.96 24. Ling Li, et al., Shaohua Yao*, Changyang Gong*, Yuquan Wei*. Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice. ACS Nano, 2017, 11(1), 95-111. IF=13.334 23. Tao He, et al., Yingtai Chen*, Changyang Gong*. Improving anti-adhesion effect of thermosensitive hydrogel with sustained release of tissue-type plasminogen activator in a rat repeated-injury model. ACS Appl Mater Inter, 2016, 8(49), 33514-33520. IF=7.145 22. Ling Li, et al., Changyang Gong*. Multifunctional “core-shell” nanoparticles-based gene delivery for treatment of aggressive melanoma. Biomaterials, 2016, 111, 124-137. IF=8.387 21. Linjiang Song, et al., Li Yang*, Qinjie Wu*, Changyang Gong*. Peritoneal adhesion prevention with a biodegradable and injectable N,O-carboxymethyl chitosan-aldehyde hyaluronic acid hydrogel in a rat repeated-injury model. Sci Rep, 2016, 6, 37600. IF=5.228 20. Huaimin Wang, et al., Changyang Gong*, Xingyi Li*, Zhimou Yang*. Enzyme-Catalyzed Formation of Supramolecular Hydrogelsas Promising Vaccine Adjuvants. Adv Funct Mater, 2016, 26 (11), 1822-1829. IF=11.382 19. Ning Wang, et al., Changyang Gong*. Paclitaxel and tacrolimus co-encapsulated polymeric micelles enhance therapeutic effect of drug-resistant ovarian cancer. ACS Appl Mater Inter, 2016, 8, 4368-4377. IF=7.145 18. Qinjie Wu, et al., Changyang Gong*. Thermosensitive hydrogel containing dexamethasone micelles for preventing postsurgical adhesion in a repeated-injury model. Sci Rep, 2015, 5, 13533. IF=5.228 17. Xi Yang, et al., Changyang Gong*. Curcumin-encapsulated polymeric micelles suppress the development of colon cancer in vitro and in vivo. Sci Rep, 2015, 5, 10332. IF=5.228 16. Senyi Deng, et al., Changyang Gong*. Biodegradable polymeric micelle-encapsulated doxorubicin suppresses tumor metastasis by killing circulating tumor cells. Nanoscale, 2015, 7, 5270-5280. IF=7.76 15. Nannan Zhang, et al., Changyang Gong*.Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathway. Nanoscale, 2015,7(6), 2609-2624. IF=7.76 14. Yishan Chen,et al., Changyang Gong*. Polymeric micelles encapsulating fisetinimprove the therapeutic effect in colon cancer. ACS Appl Mater Inter, 2015, 7(1), 534-542. IF=7.145 13. Qinjie Wu, et al., Changyang Gong*. Enhanced antitumor activity and mechanism of biodegradable polymeric micelles-encapsulated chetomin in both transgenic zebrafish and mouse models. Nanoscale, 2014, 6(20): 11940-11952. IF=7.76 12. Yuanyuan Liu, et al., Changyang Gong*, YoufuLuo*. Biodegradable nanoassemblies of piperlongumine display enhanced antiangiogenesis and antitumor activities. Nanoscale, 2014, 6, 4325-4337. IF=7.76 11. Ling Li, et al., Changyang Gong*. Biodegradable and injectable hydrogel based on chitosan and hyaluronan for prevention of postoperative adhesion. Biomaterials, 2014, 35(12), 3903-3917.IF=8.387 10. Qinjie Wu, et al., ChangYang Gong*. Biodegradable polymeric micelle-encapsulated quercetin suppresses tumor growth and metastasis in both transgenic zebrafish and mouse models. Nanoscale 2013, 5(24): 12480-12493. IF=7.76 9. ChangYang Gong, et al., Zhiyong Qian*. A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing. Biomaterials 2013, 34(27): 6377-6387. IF=8.387 8. ChangYang Gong*, et al. Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles. Biomaterials 2013, 34: 1413-1432. IF=8.387标签: 四川大学 生物治疗国家重点实验室
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