个人简历

2016/09-2018/09 斯坦福大学，医学院，访问学者 2012/09-至今 四川大学，华西药学院，教学科研 2009/04-2012/03 京都大学，药学院，博士 2004/09-2007/06 四川大学，华西药学院，硕士 2000/09-2004/07 四川大学，华西药学院，学士

研究领域

1.分子影像药学 2.药物质量控制与药物代谢分析

近期论文

1. Zhu BY, Cheng Y, Li GB, Yang SY, Zhang ZR. Synthesis and evaluation of styrylpyran fluorophores for noninvasive detection of cerebral β-amyloid deposits. Bioorg Med Chem. 2016 Feb 15;24(4):827-34。 2.Cheng Y,* Zhu B, Deng Y, Zhang Z. In vivo detection of cerebral amyloid fibrils with smart dicynomethylene-4H-pyran-based fluorescence probe. Anal. Chem. 2015 5;87(9):4781-7. doi: 10.1021/acs.analchem.5b00017. 3. Cheng Y,* Zhu BY, Li X, Li GB, Yang SY, Zhang ZR. Bioorg. Med. Chem. Lett. 2015, 25(20):4472-6. doi: 10.1016/j.bmcl.2015.08.081. 4. Masahiro Ono *, Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto , Masafumi Ihara, Ryosuke Takahashi, Hideo Saji. Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer's Disease. PLoS One.，8(9):e74104, 2013. 5. Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Hideo Saji. Technetium-99m Labeled Pyridyl Benzofuran Derivatives as Single Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer’s Brains. J. Med. Chem. 55(5), 2279-2286, 2012 6. Masahiro Ono*, Yan Cheng, Hiroyuki Kimura, Mengchao Cui, Shinya Kagawa, Ryuichi Nishii, Hideo Saji. Novel 18F-Labeled Benzofuran Derivatives with Improved Properties for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques in Alzheimer's Brains. J. Med. Chem. 54(8), 2971-2979, 2011 7. Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hideo Saji. Fluorinated Benzofuran Derivatives for PET Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains. ACS Med. Chem. Lett. 1(7), 321-325, 2010 8. Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hideo Saji. A Novel 18F-Labeled Pyridyl Benzofuran Derivative for Imaging of β-Amyloid Plaques in Alzheimer's Brains. Bioorg. Med. Chem. Lett. 20(20), 6141–6144, 2010 9. Masahiro Ono*, Manami Ishikawa, Hiroyuki Kimura, Shun Hayashi, Kenji Matsumura, Hiroyuki Watanabe, Yoichi Shimizu, Yan Cheng, Mengchao Cui, Hidekazu Kawashima, Hideo Saji, Development of Dual Functional SPECT/Fluorescent Probes for Imaging Cerebral β-amyloid Plaques. Bioorg. Med. Chem. Lett. 20(13), 3885–3888, 2010 10. Masahiro Ono*, Rumi Watanabe, Hidekazu Kawashima, Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe,Mamoru Haratake, Hideo Saji, and Morio Nakayama, Fluoro-pegylated Chalcones as Positron Emission Tomography Probes for in vivo Imaging of β-amyloid Plaques in Alzheimer's Disease. J. Med. Chem. 52(20), 6394–6401, 2009.