包锐
近期热点
资料介绍
个人简历
2009年在同济大学获得理学博士学位。2009年 - 2014年,在美国国立健康研究院,美国国立癌症研究所从事博士后研究工作。2014年受聘于四川大学生物治疗国家重点实验室,任研究员。研究领域
(1) 病原菌致病因子的结构与功能 (2) 病原菌与宿主侵染机制 (3) 革兰氏阴性菌耐药机制 (4) 抗菌疫苗与新型抗菌药物的研发近期论文
1. Bao, R.; Nair, M. K.; Tang, W. K.; Esser, L.; Sadhukhan, A.; Holland, R. L.; Xia, D.; Schifferli, D. M., Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis. Proc Natl Acad Sci U S A 2013, 110 (3), 1065-70. 2. Bao, R.; Fordyce, A.; Chen, Y. X.; McVeigh, A.; Savarino, S. J.; Xia, D., Structure of CfaA suggests a new family of chaperones essential for assembly of class 5 fimbriae. PLoS Pathog 2014, 10 (8), e1004316. 3. Bao, R.; Zhou, C. Z.; Jiang, C.; Lin, S. X.; Chi, C. W.; Chen, Y., The ternary structure of the double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation. J Biol Chem 2009, 284 (39), 26676-84. 4.Bao, R.; Liu Y.; Savarino SJ.; Xia, D. Off-pathway assembly of fimbria subunits is prevented by chaperone CfaA of CFA/I fimbriae from enterotoxigenic E.coli. Mol Microbiol 2016, 102(6), 978-991 5. Bao, R.; Zhang, Y.; Zhou, C. Z.; Chen, Y., Structural and mechanistic analyses of yeast mitochondrial thioredoxin Trx3 reveal putative function of its additional cysteine residues. Biochim Biophys Acta 2009, 1794 (4), 716-21. 6. Bao, R.; Zhang, Y.; Lou, X.; Zhou, C. Z.; Chen, Y., Structural and kinetic analysis of Saccharomyces cerevisiae thioredoxin Trx1: implications for the catalytic mechanism of GSSG reduced by the thioredoxin system. Biochim Biophys Acta 2009, 1794 (8), 1218-23.标签: 四川大学 生物治疗国家重点实验室
相关热点
最新收录
- 生野光 (生野ひかる Hika 06-14
- 乙都咲乃 (乙都さきの S 06-14
- 工藤丽华 (工藤れいか R 06-14
- 川原香苗 (川原かなえ K 06-14
- 滝口理奈 (滝口りな Rina 06-14
- 枫夏希(楓なつき Natsuki 06-14
- 堇潤 (すみれ潤 Jun Sumire 06-14
- 佐野结菜 (佐野ゆいな Y 06-14
- 佐藤白音 (さとう白音 S 06-14
- 丘惠理奈 (丘えりな Oka 06-14