个人简历

教育与工作经历\r
1981.09—1985.07 华南工学院应用化学系本科 理学学士\r
1985.11—1986.07 国家教委出国预备研究生(华南工学院)\r
1986.10—1989.03 日本宇都宫大学大学院应用化学专业 工学硕士\r
1989.03—1992.03 日本东京工业大学大学院化学工程专业 工学博士\r
1992.4-1998.2 日本东京工业大学生命理工学部 助理教授\r
1997.5-1997.7 中国科学院化工冶金研究所国家生化工程重点实验室客座研究员\r
1998.3-2001.7 日本横滨国立大学工学部物质工学专业 讲师、副教授\r
1999.7-1999.10 清华大学化工系客座教授\r
2000.9-现在 清华大学化工系教授、百名人才工程入选者\r
2002.9-现在 担任清华大学化工系生物化工研究所所长\r
2012-现在 工业生物催化教育部重点实验室副主任\r
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学术荣誉与奖励\r
1993年获得日本财团法人手岛工业教育基金团研究纪念奖\r
2002年获得清华大学第五届“良师益友”荣誉称号\r
2004年获得日本竹田国际交流（生物工程领域）贡献奖\r
2007年获得第17届全国发明展览会奖银奖\r
2008年获得北京市科学技术奖三等奖\r
2009年获得中国石油和化学工业协会技术发明奖二等奖\r
2010年获得中国侨界贡献奖（创新人才）和首都新侨乡创新发展先进个人称号\r
2012年获得中国食品产业产学研创新发展“杰出科研人才领军人物奖”\r
2017年获日内瓦国际发明博览会金奖

研究领域

"以整合生物技术为研究方向，为工业生物技术和环境生物工程提供核心技术和工艺，具体包括：工业生物催化、合成生物学、微生物代谢工程、生物纳米技术"

近期论文

Liu, Zhidan; Si, Buchun; Li, Jiaming; He, Jianwei; Zhang, Chong; Lu, Yuan; Zhang, Yuanhui; Xing, Xin-Hui, Bioprocess engineering for biohythane production from low-grade waste biomass: technical challenges towards scale up. CURRENT OPINION IN BIOTECHNOLOGY, 2018, 50():25-31.\r
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Wang, Tianmin; Guan, Changge; Guo, Jiahui; Liu, Bing; Wu, Yinan; Xie, Zhen; Zhang, Chong; Xing, Xin-Hui, Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance. NATURE COMMUNICATIONS, 2018, 9():-.\r
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Zhou, Yikang; Li, Gang; Dong, Junkai; Xing, Xin-hui; Dai, Junbiao; Zhang, Chong, MiYA, an efficient machine-learning workflow in conjunction with the YeastFab assembly strategy for combinatorial optimization of heterologous metabolic pathways in Saccharomyces cerevisiae. METABOLIC ENGINEERING, 2018, 47():294-302.\r
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Ji, Yang; Lu, Yuan; Yan, Yishu; Liu, Xinxin; Su, Nan; Zhang, Chong; Bi, Shengli; Xing, Xin-Hui, Design of Fusion Proteins for Efficient and Soluble Production of Immunogenic Ebola Virus Glycoprotein in Escherichia coli. BIOTECHNOLOGY JOURNAL, 2018, 13(6):-.\r
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Cui, Lan-Yu; Wang, Shan-Shan; Guan, Chang-Ge; Liang, Wei-Fan; Xue, Zheng-Lian; Zhang, Chong; Xing, Xin-Hui, Breeding of Methanol-Tolerant Methylobacterium extorquens AM1 by Atmospheric and Room Temperature Plasma Mutagenesis Combined With Adaptive Laboratory Evolution. BIOTECHNOLOGY JOURNAL, 2018, 13(6):-.\r
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Guo, Jiahui; Wang, Tianmin; Guan, Changge; Liu, Bing; Luo, Cheng; Xie, Zhen; Zhang, Chong; Xing, Xin-Hui, Improved sgRNA design in bacteria via genome-wide activity profiling. NUCLEIC ACIDS RESEARCH, 2018, 46(14):7052-7069.\r
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Liang, Wei-Fan; Cui, Lan-Yu; Cui, Jin-Yu; Yu, Kai-Wen; Yang, Song; Wang, Tian-Min; Guan, Chang-Ge; Zhang, Chong; Xing, Xin-Hui, Biosensor-assisted transcriptional regulator engineering for Methylobacterium extorquens AM1 to improve mevalonate synthesis by increasing the acetyl-CoA supply. METABOLIC ENGINEERING, 2017, 39():159-168.\r
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Liu, Shu-De; Wu, Yi-Nan; Wang, Tian-Min; Zhang, Chong; Xing, Xin-Hui, Maltose Utilization as a Novel Selection Strategy for Continuous Evolution of Microbes with Enhanced Metabolite Production. ACS SYNTHETIC BIOLOGY, 2017, 6(12):2326-2338.\r
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Yan, Yishu; Ji, Yang; Su, Nan; Mei, Xiang; Wang, Yi; Du, Shanshan; Zhu, Wenming; Zhang, Chong; Lu, Yuan; Xing, Xin-Hui, Non-anticoagulant effects of low molecular weight heparins in inflammatory disorders: A review. CARBOHYDRATE POLYMERS, 2017, 160():71-81.\r
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Tian, Xingguo; Chen, Xin; Dai, Lingmei; Du, Wei; Liu, Dehua, A novel process of lipase-mediated biodiesel production by the introduction of dimethyl carbonate. CATALYSIS COMMUNICATIONS, 2017, 101():89-92\r
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Fang, Mingyue; Wang, Tianmin; Zhang, Chong; Bai, Jili; Zheng, Xiang; Zhao, Xuejin; Lou, Chunbo; Xing, Xin-Hui, Intermediate-sensor assisted push-pull strategy and its application in heterologous deoxyviolacein production in Escherichia coli. METABOLIC ENGINEERING, 2016, 33():41-51. 引用:25\r
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Li, Gang; Huang, Ziliang; Zhang, Chong; Dong, Bo-Jun; Guo, Ruo-Hai; Yue, Hong-Wei; Yan, Li-Tang; Xing, Xin-Hui, Construction of a linker library with widely controllable flexibility for fusion protein design. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016, 100(1):215-225. 引用:22\r
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Si, Bu-Chun; Li, Jia-Ming; Zhu, Zhang-Bing; Zhang, Yuan-Hui; Lu, Jian-Wen; Shen, Rui-Xia; Zhang, Chong; Xing, Xin-Hui; Liu, Zhidan, Continuous production of biohythane from hydrothermal liquefied cornstalk biomass via two-stage high-rate anaerobic reactors. BIOTECHNOLOGY FOR BIOFUELS, 2016, 9():-.\r
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Zhang, Shou-Chi; Lai, Qi-Heng; Lu, Yuan; Liu, Zhi-Dan; Wang, Tian-Min; Zhang, Chong; Xing, Xin-Hui, Enhanced biohydrogen production from corn stover by the combination of Clostridium cellulolyticum and hydrogen fermentation bacteria. JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2016, 122(4):482-487.\r
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Huang, Ziliang; Li, Gang; Zhang, Chong; Xing, Xin-Hui, A study on the effects of linker flexibility on acid phosphatase PhoC-GFP fusion protein using a novel linker library. ENZYME AND MICROBIAL TECHNOLOGY, 2016, 83():1-6.\r
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Guo, Jun; Wang, Niejun; Peng, Liao; Wu, Jingjun; Ye, Qiquan; Feng, Anchao; Wang, Zhipeng; Zhang, Chong; Xing, Xin-Hui; Yuan, Jinying, Electrochemically-responsive magnetic nanoparticles for reversible protein adsorption. JOURNAL OF MATERIALS CHEMISTRY B, 2016, 4(22):4009-4016.\r
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Wang, Cheng-Hua; Zhang, Chong; Xing, Xin-Hui, Xanthine dehydrogenase: An old enzyme with new knowledge and prospects. BIOENGINEERED, 2016, 7(6):395-405.\r
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Lu, Yuan; Zhao, Hongxin; Zhang, Chong; Xing, Xin-Hui, Insights into the global regulation of anaerobic metabolism for improved biohydrogen production. BIORESOURCE TECHNOLOGY, 2016, 200():35-41.\r
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Liu, Zhidan; Zhang, Chong; Wang, Linjun; He, Jianwei; Li, Baoming; Zhang, Yuanhui; Xing, Xin-Hui, Effects of furan derivatives on biohydrogen fermentation from wet steam-exploded cornstalk and its microbial community. BIORESOURCE TECHNOLOGY, 2015, 175():152-159.\r
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Zhang, Xue; Zhang, Chong; Zhou, Qian-Qian; Zhang, Xiao-Fei; Wang, Li-Yan; Chang, Hai-Bo; Li, He-Ping; Oda, Yoshimitsu; Xing, Xin-Hui, Quantitative evaluation of DNA damage and mutation rate by atmospheric and room-temperature plasma (ARTP) and conventional mutagenesis. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015, 99(13):5639-5646.