个人简历

1997.9－2001.7 曲阜师范大学生命科学学院 学士\r
2001.9－2007.1 中科院上海生物化学与细胞生物学研究所 博士\r
2007.8－2012.8 美国索儿克研究所 博士后\r
2012.8－ 清华大学生命科学学院 副教授

研究领域

"能量稳态的激素信号调控：1）经典激素调控能量稳态的新的分子机制；2）高等生物特有的新的激素及其对能量稳态的调控；3）新的调控机制在糖尿病及肿瘤等代谢性疾病中的作用。"

近期论文

Yi Liu#, Yuanyuan Zhang#, Tong Li, Jinbo Han and Yiguo Wang*. (2020) The tight-junction protein TJP1 regulates the feeding-modulated hepatic circadian clock. Nat Commun. 11(1), 589.\r
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Erwei Li#, Haili Shan#, Liqun Chen#, Aijun Long#, Yuanyuan Zhang#, Yang Liu, Liangjie Jia, Fangchao Wei, Jinbo Han, Tong Li, Xiaohui Liu, Haiteng Deng and Yiguo Wang*. (2019) OLFR734 mediates glucose metabolism as a receptor of Asprosin. Cell Metab. 30, 319-328.\r
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Liqun Chen#, Ke Wang#, Aijun Long, Liangjie Jia, Yuanyuan Zhang, Haiteng Deng, Yu Li, Jinbo Han and Yiguo Wang*. (2017) Fasting-induced hormonal regulation of lysosomal function. Cell Res. 27, 748-763.\r
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Jinbo Han#, Erwei Li#, Liqun Chen, Yuanyuan Zhang, Fangchao Wei, Jieyuan Liu, Haiteng Deng and Yiguo Wang*. (2015). The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. Nature 524, 243-246.\r
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Yiguo Wang, Gang Li, Jason Goode, Jose C. Paz, Kunfu Ouyang, Robert Screaton, Wolfgang H. Fischer, Ju Chen, Ira Tabas and Marc Montminy*. (2012). InsP3 receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature 485, 128-132. \r
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Yiguo Wang, Hiroshi Inoue, Kim Ravnskjaer, Kristin Viste, Nina Miller, Yi Liu, Susan Hedrick, Liliana Vera, and Marc Montminy*. (2010). Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proc Natl Acad Sci U S A. 107, 3087-3092. \r
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Yiguo Wang, Liliana Vera, Wolfgang H Fischer, Marc Montminy*. (2009). The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature 460, 534-537. \r
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Yiguo Wang, Dan Du, Longhou Fang, Guang Yang, Chenyi Zhang, Rong Zeng, Axel Ullrich, Friedrich Lottspeich, Zhengjun Chen*. Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. The EMBO Journal. (2006) 25, 5058-5070.