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马剑鹏
2023-05-12 11:47
  • 马剑鹏
  • 马剑鹏 - 教授 博导-清华大学-生物信息学教育部重点实验室-个人资料

近期热点

资料介绍

个人简历


教育经历: 1981-1985 就读于复旦大学化学系,获化学学士学位 1990-1996 就读于Boston University,获化学博士学位 工作经历: 1996-2000 哈佛大学化学系博士后 2000-2004 贝勒医学院生物化学和分子生物学系及莱斯大学生物工程系助理教授 2004-2008 贝勒医学院生物化学和分子生物学系及莱斯大学生物工程系副教授 2008-2010 贝勒医学院生物化学和分子生物学系及莱斯大学生物工程系教授 2010-present 贝勒医学院生物化学和分子生物学系及莱斯大学生物工程系Lodwick T. Bolin讲席教授

研究领域


计算生物学:全力发展新的计算方法来模拟生物体系,改良结构建模,和准确预测蛋白质和核糖核酸结构。细胞和结构生物学:利用生物化学、分子生物学、细胞生物学、发育生物学和生物信息学等多学科技术手段研究肌球蛋白的信号传递以及表观遗传因子在胚胎干细胞和肿瘤细胞发育中的作用。

近期论文


Yinghao Wu and Jianpeng Ma (2004). Refinement of F-actin Model Against Fibre Diffraction Data by Long range Normal Modes. Biophys. J. 86: 116-124. Jacob Brink, Steven J. Ludtke, Yifei Kong, Salih J. Wakil, Jianpeng Ma and Wah Chiu (2004). Experimental Verification of Conformational Variation of Human Fatty Acid Synthase as Predicted by Normal Mode Analysis. Structure 12:185-191. Jianpeng Ma (2004). New Advances in Normal Mode Analysis of Supermolecular Complexes and Applications to Structural Refinement. Curr. Prot. Pept. Sci 5:119-123 (Invited review). Terence C. Flynn and Jianpeng Ma (2004). Theoretical analysis of twist/bend ratio and mechanical moduli of bacterial flagellar hook and filament. Biophys. J. 86: 3204-3210. Yifei Kong, Xing Zhang, Timothy S. Baker and Jianpeng Ma (2004). A Structural-informatics Approach for Tracing b-sheets: Building Pseudo-Ca-traces for b-strands in Intermediate-Resolution Density Maps. J. Mol. Biol. 339: 117-130. Arjan van der Vaart, Jianpeng Ma and Martin Karplus (2004). The Unfolding Action of GroEL on A Protein Substrate. Biophys. J. 87:562-573. Qiang Cui, Guohui Li, Jianpeng Ma and Martin Karplus (2004). A Normal Mode Analysis of Structural Plasticity in the Biomolecular Motor F1-ATPase. J. Mol. Biol. 340:345-372. Yinghao Wu and Jianpeng Ma (2004). Normal-mode-based Refinement of an F-actin Model Against Fibre Diffraction Data. Fibre Diffraction Review 12: 25-28 (Invited review). Martin Karplus, Yi Qin Gao, Jianpeng Ma, Arjan van der Vaart, and Wei Yang (2005). Protein Structural Transitions and Their Functional Role. Phil. Trans. R. Soc. A 363: 331-356. Jianpeng Ma (2005). Usefulness and Limitations of Normal Mode Analysis in Modeling Dynamics of Biomolecular Complexes. Structure 13: 373-380. Yechun Xu, Jianhua Shen, Xiaomin Luo, Weiliang Zhu, Kaixian Chen, Jianpeng Ma and Hualiang Jiang (2005). Conformational Transition of Amyloid beta-peptide. Proc. Natl. Acad. Sci. USA. 102: 5403-5407. B. K. Muralidhara, Mingzhi Chen, Jianpeng Ma, and Pernilla Wittung-Stafshede (2005). Effect of Inorganic Phosphate on FMN Binding and Loop Flexibility in Desulfovibrio desulfuricans Apo-falvodoxin. J. Mol. Biol. 349:87-97. Sergei Trakhanov, Nand K. Vyas, Hartmut Luecke, David M. Kristensen, Jianpeng Ma, and Florante A. Quiocho (2005). Ligand-free and -bound Structures of the Binding Protein (LivJ) of the Escherichia coli ABC Leucine/Isoleucine/Valine Transport System: Trajectory and Dynamics of the Interdomain Rotation and Ligand Specificity. Biochemistry. 44:6597-6608. Yinghao Wu, Mingzhi Chen, Mingyang Lu, Qinghua Wang, and Jianpeng Ma (2005). Determining Protein Topology from Skeletons of Secondary Structures. J. Mol. Biol. 350:571-586. L. Elchlnger, ...., Jianpeng Ma et al. (2005). The Genome of the Social Amoda Dictyostelium Discoideum. Nature 435:43-57. Mingyang Lu and Jianpeng Ma (2005). The Role of Shape in Determining Molecular Motions.Biophys. J. 89:2395-2401. Yinghao Wu, Xia Tian, Mingyang Lu, Mingzhi Chen, Qinghua Wang and Jianpeng Ma (2005). Folding of Small Helical Proteins Assisted by Small Angle X-ray Scattering Profiles. Structure13:1587-1597. Michael Perham, Mingzhi Chen, Jianpeng Ma, and Pernilla Wittung-Stafshede (2005). Unfolding of Heptameric Co-chaperonin Protein Follows \

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